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BONE TUMORS

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Blood testing: Multiple Myeloma 11. Biopsy: open; needle Problems 1. Pathological fracture 2. Deformity 3. Growth plate involvement 4. Pain 5. Tenderness ... – PowerPoint PPT presentation

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Title: BONE TUMORS


1
BONE TUMORS
  • Pamela Gregory-Fernandez
  • RPA-C

2
Benign Primary Bone Tumors
  • Definition tumors that arise from cells of
    mesenchymal origin
  • Bone cartilage fibrous tissue round cells
  • Bone cyst fibrous lesion osteochondrome
    giant cell tumor chondroma osteoid osteoma

3
Diagnosis
  • 1. H P
  • 2. Three age groups children young adults
    older adults gt 40 yo
  • 3. How was the tumor discovered ?
  • Incidental finding on x-ray
  • Mass
  • Pain
  • Pathological fracture
  • 4. BEWARE masses in the KNEE, SHOULDER, BUTTOCK

4
  • 5. Plain x-rays
  • A. Location of the tumor in the bone
  • B. Reaction of the tumor/bone complex
  • 6. MRI
  • A. Anatomic location and extent of tumor
  • B. Soft tissue involvement
  • C. Bone marrow involvement
  • 7. Bone Scan
  • A. Multiple lesions
  • 8. CAT Scan
  • 9. Special Imaging
  • 10. Blood testing Multiple Myeloma
  • 11. Biopsy open needle

5
Problems
  • 1. Pathological fracture
  • 2. Deformity
  • 3. Growth plate involvement
  • 4. Pain
  • 5. Tenderness
  • 6. Neurovascular compromise
  • 7. Joint motion restriction

6
Treatment
  • 1. Excision
  • 2. Curettge and bone grafting

7
Malignant Primary Bone Tumors
  • Sarcoma a malignant tumor arising from cells
    of mesenchymal origin
  • 1. metastasizes by the blood stream
  • 2. very aggressive
  • 3. poor response to radio or chemotherapy
  • Examples osteosarcoma (most common)
  • Fibrosarcoma Ewings sarcoma multiple myelome
    chondrosarcoma

8
Clinical Features / Diagnosis
  • Younger age group
  • Except myeloma
  • Pain
  • Night
  • Progressive
  • Mass
  • Pathological fracture
  • Bone not deformed
  • 1. Staging
  • A. CT MRI arteriograms scans clinical
  • B. Grade I II III distant mets
  • C. Intra vs. Extracompartmental
  • 2. Biopsy

9
Treatment
  • 1. Wide margin excision, may mean amputation,
    with adjunctive RT and/or chemotherapy
  • 2. Limb salvage with adjunctive RT and/or
    chemotherapy
  • Custom made total joints
  • Large bone allografts

10
Osteosarcoma
  • 1. MOST COMMON
  • 2. males
  • 3. second decade
  • 4. metaphysis
  • 5. distal femur, proximal tibia, humerus
  • 6. Spindle cell sarcoma
  • 7. x-ray CODMANS TRIANGLE
  • 8. pain
  • 9. soft tissue mass

11
Ewings Sarcoma
  • 5-30 years old
  • Second most common
  • Pain of involved extremity
  • May follow trauma
  • FEVER, FATIGUE, MALAISE, WEIGHT LOSS
  • Micromets at presentation

12
Benign Tumors
13
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