Title: DISORDERS OF THE GENITO-URINARY IN CHILDREN
1DISORDERS OF THE GENITO-URINARY SYSTEM IN
CHILDREN
2Aim
To show an in-depth understanding of the
genito-urinary disorders in children and the
process of care in the nursing management
3Learning Objectives
- By the end of this session, the student
- should be able to
- Understand the anatomy and physiology of the
renal system and structure and function - Identify the differences between adult and
children GU system - Describe the most common diagnostic
investigations and procedures for GU disorders
4Learning Objectivescont
- Understand the general assessment of children
with genitourinary disorders - Understand the common genitourinary disorders in
children - Plan the nursing management for children with GU
disorders
5PAEDIATRIC DIFFERENCES OF KIDNEY DEVELOPMENT
- Begins during 1st week of gestation
- Completed by end of 1st year after birth
- Excretion less than adult
- By the age of 6 to 12 months, filtration and
absorption is nearly like adults - For healthy infant, the kidneys operate at a
functional level appropriate for the size of the
body.
6Function of Kidney
- Nephron
- Glomeruli filter water and solutes from blood
- Tubules reabsorb needed substances (water,
protein, electrolytes, glucose, amino acids) from
filtrate and allow unneeded substances to leave
the body in urine - Urine formed in the nephron, passes into renal
pelvis, through ureter into bladder and out of
body through urethra
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8Urine formed in the nephron, passes into renal
pelvis, through ureter into bladder and out of
body through urethra
9Glomeruli filter water and solutes from blood
Tubules reabsorb needed substances (water,
protein, electrolytes, glucose, amino acids)
from filtrate and allow unneeded substances to
leave the body in urine
10Function of Kidney
- Maintaining body fluid volume and composition
- Secretes hormones-
- Renin helps with the regulation of blood
pressure - Erythropoietin stimulates red blood cell
production by the bone marrow - Metabolised Vitamin D responsible for calcium
metabolism
11Diagnostic Investigations
- Urinalysis
- CT Scan- an x-ray procedure that combines many
x-ray images with the aid of a computer to
generate cross-sectional views and, if needed,
three-dimensional images of the internal organs
and structures of the body.
12Blood urea nitrogen (B.U.N) and creatinine -
- gross indicator of renal function
- (BUN) test measures the amount of nitrogen in
blood that comes from the waste product urea. - Urea is made when protein is broken down in body.
- Blood urea nitrogen (BUN) and creatinine tests
can be used together to find the
BUN-to-creatinine ratio (BUNcreatinine). body in
the urine. - A blood urea nitrogen (BUN) test is done to
determine - kidneys are working normally.
- kidney disease is getting worse.
- See if treatment of kidney disease is working.
- See if severe dehydration is present. Dehydration
generally causes BUN levels to rise more than
creatinine levels. This causes a high
BUN-to-creatinine ratio. Kidney disease or
blockage of the flow of urine from kidney causes
both BUN and creatinine levels to go up.
13Cystoscopy bladder and urethra are examined
with cystoscope (fibre optic technology)
14- KUB (Kidney, Ureter, Bladder) x-ray
- Renal Biopsy
Renal Ultrasound
15Intravenous pyelogram (IVP)
- An injection of x-ray contrast media via a needle
or cannula into the vein, typically in the arm.
The contrast is excreted or removed from the
bloodstream via the kidneys, and the contrast
media becomes visible on x-rays almost
immediately after injection
16Retrograde Pyelogram
- a urologic procedure where the physician injects
contrast into the ureter in order to visualize
the ureter and kidney. - Micturating Cystourethrography (MCUG) serial
x-ray of the bladder and urethra after IV
infusion of iodine-bound contrast medium ( to
detect blockage)
17COMMON DISORDERS OF THE GENITOURINARY SYSTEM
- Urinary tract infection (UTI)
- Nephrotic syndrome
- Acute Post-Streptococcal Glomerulonephritis
(APSGN) - Vesicoureteral reflux
- Hypospadias
18URINARY TRACT INFECTIONS
- Definition
- UTI is the presence of bacteria in the urine
- Infection usually occur at the upper urinary
tract or at the lower urinary tract - Incidence
- Common age of onset for UTI is 2-6 years
- GirlgtBoy - Female has shorter urethra
- Uncircumcised male prone to develop UTI
19Causes
- Causative organisms E. Coli
- Route of entry -bacteria ascending from the area
outside of the urethra. - Vesico-ureteral reflux
- Infections URTI, GE
- Poor perineal hygiene - fecal organisms are the
most common infecting organisms due to the
proximity of the rectum to the urethra. - Short female urethra
20Types of UTI
- Urethritis infection of the urethra
- Cystitis an infection in the bladder that has
moved up from the urethra - Pyelonephritis a urinary infection of the
kidney as a result of an infection in the urinary
tract
21Diagram of cystitis
22Unexplained fever (febrile fits)
Poor growth
Abdominal pain
Foul-smelling urine
Signs Symptoms of UTI in babies
Irritability
Poor feeding
Weight loss (failure to weight gain)
Vomiting
23Signs Symptoms of UTI in older children
- Urinary frequency/urgency
- Dysuria
- Foul-smelling urine
- Cloudy urine
- Incontinence during day and/or night
- Increased irritability
- Nausea and vomiting
- Low abdominal or flank pain
- Fever and chills
- Fatigue
- Small amount of urine while micturating despite
feeling of urgency
24Signs of serious infections
- Central pyrexia but peripherally cold
- Poor colour
- Pale, grey mottled skin
- Quiet and lethargic child
- Poor tone
- Tachycardic and hypertensive
25Diagnostic investigations
- Obtaining a urine specimen-
- - Urine bag
- - Clean catch urine
- - Mid-stream urine
- - Catheterisation
- - Supra-pubic aspiration-draining the bladder by
inserting a sterile needle through the skin above
the pubic arch and into the bladder.
26Diagnostic investigations
- Ultrasound
- Plain x-ray
- Micturating Cystourethrogram (MCUG)
27Nursing care
- Obtain urine specimen before antibiotics started,
sent for ME/CS - Blood tests
- Strict I/O chart
- Monitor vital signs esp. body temperature
- Administer antibiotics as prescribed (5 days
course) - Administer anti-pyretic drugs to reduce fever and
pain - Advised to take plenty of fluids to prevent
dehydration and to flush the urinary tract - If the child is unable (vomiting) or refuse to
take fluids, administer IV fluids as prescribed
28Nursing Problems
- Fever due to increased body temperature related
to urinary tract infection. - Alteration in urination (frequency, pain,
burning, dribbling and enuresis) related to
infection. - Pain related to inflammatory changes in the
urinary tract. - Lack of knowledge about UTI and health prevention
29 Problem 1 Fever due to increased
bodytemperature related to urinary tract
infection
Goal to reduce fever and maintain normal body
temperature
Nursing interventions Rationales
monitor body temperature every 4º encourage plenty of fluid intake administer anti-pyrexial medications as prescribed maintain bed rest wear thin loose clothing give tepid-sponging with luke-warm water baseline obs. to maintain hydration to maintain an optimum body temp. to reduce the body heat to reduce body heat
30 Problem 2 Alteration in urination (frequency,
pain, burning, dribbling and enuresis) related
to infection
Goal to ensure that the child is comfortable
during urination
Nursing interventions Rationales
assess the urinary frequency, pain or burning sensation during micturation assess the colour odour of urine strict I/O chart administer antibiotics as prescribed observe for signs symptoms of serious infection as baseline obs. as baseline obs. to observe urinary frequency to prevent spread of infection to prevent complications
31Health teaching to prevent UTI
- Ensure the child to pass urine regularly (every
2-3 hours) and take the time to completely empty
the bladder - Avoid holding urine for prolonged period of time
- Perineal hygiene - wipe from front to back
- Avoid tight fitting clothing or diapers wear
cotton panties - Avoid constipation
- Encourage fluid intake
- Avoid bubble baths
32Students Activity
- You are required to do the nursing care plan for
problem no. 3 4, including nursing
interventions and rationales
33Nephrotic Syndrome
Nephrotic Syndrome
34What is Nephrotic Syndrome?
- Alteration of glomerular membrane permeability
with massive proteinuria, hypoalbuminaemia,
hyperlipidaemia and oedema
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36Causes
- It occurs when the filters in the kidney leak an
excessive amount of protein. The level of protein
in the blood ? and this allows fluid to leak
across the blood vessels into the tissues
causing oedema - Nephrotic syndrome are caused by changes in the
immune system
37Pathophysiology
- For unknown reason, the glomerular membrane,
usually impermeable to large proteins becomes
permeable. - Protein, especially albumin, leaks through the
membrane and is lost in the urine. - Plasma proteins decrease as proteinuria increase.
38- The colloidal osmotic pressure which holds water
in the vascular compartments is reduced owing to
decrease amount of serum albumin. This allows
fluid to flow from the capillaries into the
extracellular space, producing oedema. - Accumulation of fluid in the interstitial spaces
and peritoneal cavity is also increased by an
overproduction of aldosterone, which causes
retention of sodium. - There is increased susceptibility to infection
due to decreased gamma-globulin. - Causing generalised oedema
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41Incidence
- 1 50 000 children
- Males gt females
- Common age of onset is between 2 to 6 years, but
can occur at any age
42Signs Symptoms
- Oedema
- - initially noted in the
- periorbital area
- - ascites
- - intense scrotal oedema
- - striae may appear due
- to skin overstretching
- - pitting oedema
- ? weight
- ? urine output
- Proteinuria (foamy urine indicates proteinuria)
- Fatigue
- Irritable and depression
- Severe recurrent infections
- Anorexia
- Wasting of skeletal muscles
43Diagnostic investigations
- Urinalysis
- - protein 3 - 4 on dipstick
- - haematuria may be absent or microscopic
44Diagnostic investigationscont
- Blood test
- - total serum protein low
- - serum albumin low
- - cholesterol and lipoproteins high
- Renal function test often normal
- Blood pressure often normal but 25
hypertension - Renal biopsy
45Renal biopsy
46Nursing problems
- Generalised oedema due to fluid volume excess
related to glomerular dysfunction - Impaired skin integrity related to oedema
- Altered urinary pattern related to glomerular
dysfunction - Increased susceptibility to infection related to
disease process and steroid therapy
47Nursing problemscont
- Altered body image (round face) due to
side-effects of medication - Inadequate nutritional intake related to large
loss of protein from the urine - Knowledge deficit of the disease process and
treatment - Anxiety and depression due to the up and down of
the course of disease
48Nursing problem 1 Generalised oedema due
tofluid volume excess related to glomerular
dysfunction
- Goal to relieve oedema
- Nursing interventions
- Administer steroids prednisolone 2-4mg/kg to
control oedema - Observe for side-effects of steroids Cushings
syndrome (moon face, abdominal distension,
striae, ? appetite, ? weight, aggravation of
adolescent acne)
49- Administer diuretic frusemide. Diuretics can
cause loss of electrolytes esp. potassium,
encourage ? potassium food e.g. citrus fruits,
date, apricot, banana - Keep the child CRIB during periods of severe
oedema - Strict I/O chart restrict intake of fluid
offer small amount of measured fluid during
severe oedema, for infant measure the diapers
wt. - Measure daily weight and abdominal girth to
check any weight gain due to water retention
50Nursing problem 2 Impaired skin integrity
related to oedema
- Goal to protect the child from skin breakdown
- Nursing intervention
- Position the child comfortably in bed so that
oedematous skin is well-support with a pillow - Elevate the childs head to reduce peri-orbital
oedema - Provide good skin care give bath and maintain
hygiene esp. genitals and moist area - Change bedding daily and free from creases and
sharp objects to avoid cut
51Students activity
- For problems 3 9, you are required to look for
the nursing interventions yourself.
52Nursing Management
- Admission to ward
- Explain to parents nature of illness
- Blood for FBC/DC, U E, Creat., Serum lipid, CS,
LFT, serum albumin - For CXR and Echo
- Daily urine dipstick for protein, ME and CS
every morning - Daily BP, weight and abdominal girth
- Start on IV infusion
53Nursing Managementcont
- Administration of IV albumin
- Start on steroid therapy prednisolone given at
a dose of 2mg/kg/day divided into 2-3 doses. This
regimen is continued until remission is achieved - Remission is achieved when the urine is 0 or
trace for protein for 5 to 7 consecutive days - Administer prophylactic antibiotics to reduce
infections
54Nursing Managementcont
- Start on diuretic therapy frusemide (lasix)
- Dietary restriction provide ? protein, high
carbohydrate, ? potassium diet no salt diet - Strict I/O chart
- Provide careful skin care
- Good hygiene
- CRIB
55THE END
56VESICO-URETERAL REFLUX
- DEFINITION
- The backflow or reflux of urine from the bladder
into the ureters and possibly the kidneys. The
urine returns to the bladder after passing urine.
57Signs symptoms for infants
- Fever gt39ºC
- Irritability
- Poor feeding
- Vomiting
- Dysuria as evidenced by crying when passing urine
- Change in urine colour or odor
58Signs symptoms for children
- Abdominal or suprapubic pain
- Frequency in passing urine
- Urgency in passing urine
- Dysuria
- New or increased incidence of enuresis
59Pathophysiology
- In normal functioning urinary tract, there is a
valve-like mechanism at the junction of the
ureter and bladder that prevents urine from
refluxing in the ureters - As urine fills the bladder or the bladder
contracts during micturating, pressure in the
bladder occludes the opening to the ureter - When a defect occur at the vesioco-ureteral
junction, VUR occur
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61Diagnostic investigations
- MCUG to visualise the urethra, evaluate degree
of reflux and define any abnormalities - Renal scan to assess renal scarring and
function - Urodynamic studies this is done when there is
micturating dysfunction (frequency, urgency, or
incontinence) is present - Cystograms
- Urine culture
- Blood test serum creatinine
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63International Classification of Reflux
- GRADE I reflux into ureter only no dilatation
- GRADE II reflux into ureter, pelvis and calyces
with no dilaltation and normal calyceal fornices - GRADE III mild dilatation of ureter and renal
pelvis - GRADE IV moderate dilatation of ureter, pelvis
and calyces - GRADE V gross dilatation of ureter, pelvis and
calyces
64GRADE IV moderate dilatation of ureter, pelvis
and calyces
65GRADE V gross dilatation of ureter, pelvis
and calyces
66- Reflux can be divided into 2 categories -
- PRIMARY REFLUX
- - caused by abnormal position of the ureteral
bud on the wolffian duct during development of
the urinary tract, resulting in smaller, tunneled
segment of the ureter - SECONDARY REFLUX
- - occurs as a result of acquired bladder
dysfunction
67Medical management
- Daily low dose of prophylactic antibiotic to
prevent UTI - Urinalysis and urine ME/CS every 3 to 4 months
to evaluate for UTI - Monitor ?BP
68Surgical Management
- Surgery reimplantation of the ureter into the
bladder - Indicated due to recurrent UTI despite
antibiotics, Grade 5 reflux or progressive renal
injury
69HYPOSPADIAS
- Definition
- Hypospadias is a congenital anomaly in which the
actual opening of the urethral meatus is below
the normal placement on the glans of penis
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74Causes
- Occurs from incomplete development of the urethra
in utero - Exact causes unknown may be genetic,
environmental or hormonal factor
75Complications
- Stenosis of the opening could occur may lead to
UTI or hydronephrosis - May interfere with fertility if left uncorrected
- The location of the meatus may make it difficult
for the child to urinate standing up
76Surgical management
- The choice of surgical correction is affected
primarily by the severity of the defect - Surgery is done when the childs age is less than
18 months - Reconstruction of the meatal opening is done
Meatal advancement granuloplasty (MAGPI)
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78- The goal for surgical correction-
- To enhance the childs ability to pass urine in
the standing position with a straight stream - To improve the physical appearance of the
genitalia for psychological reasons - To preserve a sexually adequate organ
79References
- Ashwill, J.W. and Droske, S. C. 1997. Nursing
Care of Children. Principles and Practice. USA
W.B. Saunders. - Brunner, L.S. and Suddarth, D.S. 1986. The
Lippincott Manual of Peadiatric Nursing. (3rd
ed.) UK Chapman Hall.
80Question and Answer