Influenza and HIVAIDS

1
Influenza and HIV/AIDS

• Ida M. Onorato, M.D.
• National Center for HIV, STD and TB Prevention
• November 22, 2004

2
Influenza and HIV/AIDS

• People living with HIV/AIDS (PLWHA) are at
  increased risk of serious complications from
  influenza
• These complications include prolonged symptoms,
  hospitalization, pneumonia and death

3
Influenza Vaccination

• Influenza vaccination produces protective
  antibody and has been shown to be effective in
  PLWHA
• But persons with severe immunosuppression may not
  mount an adequate antibody response
• However, CD4 level is not clearly predictive of
  response or non-response to vaccination

4
Influenza Antivirals

• Influenza antiviral medications may be used for
  treatment or considered for chemoprophlylaxis in
  certain circumstances
• There are no published data on the the
  interactions between anti-infuenza drugs and
  HAART or other drugs used in HIV care

5
Recommendations

• CDC/ACIP have issued recommendations for 2004-
  2005 influenza season which include PLWHA and
  their care providers
• CDC has scheduled this special briefing for
  organizations and persons who care for PLWHA on
  these recommendations

6
Recommendations

• CDC/ACIP have issued recommendations for the 2004
  2005 influenza season which include PLWHA and
  their care providers
• CDC has scheduled this special briefing for
  organizations and persons who care for PLWHA on
  these recommendations