Synthesis and Characterization of Macrocyclic Polymers via Click Chemistry

1
Cyclic polymers Encapsulation of hydrocarbons
for petroleum remediation
Scott M. Grayson, Department of Chemistry, Tulane
University New Orleans, LA 70118
? Dendronized cyclic polymers enable modular
preparation of carriers with control of ring
circumference (polymer chain length) and rigidity
(dendrimer generation) as well as solubility
? Nonpolar core yet water soluble periphery
enables effective encapsulation of hydrocarbons
in aqueous solutions
Hydrophilic Corona
Hydrophobic Core
Pyrene
? Molecular modeling confirms rigid cyclic core
with large void
MOE molecular modeling
? Linear dependence of guest solubility with
host concentration suggests polymers act as
unimolecular micelles, effective even at high
dilution
Structure of dendronized cyclic polymer
? Future studies to investigate linear side
chains and quantify relative encapsulation
capacities