Central dogma: from genome to proteins II: Translation - PowerPoint PPT Presentation

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Central dogma: from genome to proteins II: Translation

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Ribosomes. Ribosome structures. Ribosome structure. A possible reaction mechanism ... The rescue of a bacterial ribosome. Frameshift. Creation of mature proteins ... – PowerPoint PPT presentation

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Title: Central dogma: from genome to proteins II: Translation


1
Central dogma from genome to proteins II
Translation
Haixu Tang School of Informatics
2
The genetic code
3
Reading frames
4
tRNA
5
Unusual nucleotides
6
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7
Amino acid activation
8
Editing of tRNA activation
9
tRNA matching
10
Peptide synthesis
11
Head vs. tail polymerization
12
Ribosomes
13
Ribosome structures
14
Ribosome structure
15
A possible reaction mechanism
16
Translation initiation
17
Structure of a typical bacterial mRNA molecule
18
Translation termination
19
Simultaneous translation
20
The rescue of a bacterial ribosome
21
Frameshift
22
Creation of mature proteins
23
Co-translational folding
24
Protein folding
25
Molecular chaperones
26
Monitoring protein quality
27
Protein degragation
28
Ubiquitin
29
Protein aggregation
30
Protein cycle in eukaryotic cell
31
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