PIGMENTS, PERFUMES AND POISONS

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? Hand in Topic of your Final Paper with a very
brief summary on your planned topic (2
pts.)Today Chemistry of plant
drugsThursday Chemistry of food (from plants)
for ThanksgivingAfter Thanksgiving Plant
Medicines. Fibers and DyesQuiz 6 on Thursday
after Thanksgiving
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• Final Paper (70 Points)
• is due Thursday, Dec. 13 (our last lecture)
• (Late Papers are NOT accepted.
• No electronic submissions)
• See back of syllabus and our class website
• for more details about Final paper

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TodayPlant Drugs

• Chemical Defenses in Plants
• Plant Toxins
• Cyanogenic glycosides
• Alkaloids
• Saponins
• Cardenolides
• Plant families

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Molecules and Descriptions
http//www.3dchem.com/atoz.asp
http//www.bris.ac.uk/Depts/Chemistry/MOTM/motm.ht
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Alkaloids
N-containing complex organic compounds from
plants Alkaline. Often bitter taste.
Papaver somniferum

• Isolation beginning 19th century
• Structure 1889
• Synthesis 1952

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Opium Composition
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Prickly Poppy
Papaverin, an opiate alkaloid in poppy species.

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Alkaloids
Ergot (Claviceps purpurea) on Rye
St. Anthonys Fire
Lysergic Acid
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Alkaloids
Albert Hoffmann 1943
http//www.bris.ac.uk/Depts/Chemistry/MOTM/motm.ht
m
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Alkaloids
Serotonin a neurotransmitter
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Alkaloids
In Psilocybe spp. (magic mushrooms)
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http//www.bris.ac.uk/Depts/Chemistry/MOTM/motm.ht
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Alkaloids
Peyote cactus (Lophophora williamsii)
http//www.bris.ac.uk/Depts/Chemistry/MOTM/motm.ht
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Alkaloids
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Alkaloids
Scopolamine an alkaloid
Datura wrightii
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Defensive plant compounds Alkaloids
N-containing complex organic compounds from
plants
Ephedrine
Ephedra
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Tetrahydrocannabinol THC
Active component in Cannabis
http//www.bris.ac.uk/Depts/Chemistry/MOTM/motm.ht
m
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Practice

• Re. the molecules below .
• which one(s) is/are aromatic?
• which one has/have a phenol ring?
• has/have chiral centers?
• which one is/are an alkaloid?
• Which is best soluble in water?

A
C
B
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Thursday Chemistry of Plant FoodsAfter
Thanksgiving Plant Medicines. Fibers and
DyesQuiz 6 on Thursday after Thanksgiving