August 26, 2005

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Lecture 12

• August 26, 2005
• Lehninger (4th Edition), Chapter 17

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FATTY ACID DEGRADATION (OXIDATION) LNC Chapter
17
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LNC 10-1
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LNC 10-6
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LNC 10-8
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LNC 10-15
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LNC 10-16
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UPTAKE and DISTRIBUTION in Mammals
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LNC 17-1
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ADIPOSE TISSUE
LNC 21-40
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Chylomicron
LNC 17-2
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Structure of an LDL particle
LNC 21-39a
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LNC 21-39b
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Breakdown/Oxidation of Fatty Acids b-Oxidation
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Activation
LNC 17-5
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LNC 17-6
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C14 fatty acid
7 acetyl CoA 6 rounds of b
oxidation
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LNC 17-7
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LNC 19-8
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How to deal with unsaturated fatty acids
cis D3 - or double bond between b-g
LNC 17-9
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LNC 17-10
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How to deal with a fatty acid containing
an uneven number of carbons
C3
C4
LNC 17-11
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LNC box 17-1
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LNC box 17-2
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Degradation of very long chain fatty acids in the
peroxisome
catalase
LNC 17-12
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Glyoxalate Cycle in Plants
LNC 17-13
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Ketone Bodies
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Conditions favoring ketone body
formation depletion of OA for
gluconeogenesis acetyl-CoA becomes available
for ketone body synthesis
LNC Fig 17-18
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Metabolic Biochemistry FATTY ACID
SYNTHESIS LNC Chapter 21
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acetyl-CoA CO2 gt malonyl-CoA
the enzyme has three functional regions -
biotin carrier protein - biotin carboxylase -
transcarboxylase
LNC Fig. 21-1
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LNC Fig. 21-4
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acyl carrier protein
LNC Fig. 21-2
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End of lecture 12 August 26, 2005