LOCK AND KEY

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Hird Hermon Industries
Proudly Present...
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LOCK AND KEY

• HYPOTHESIS

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Lock and key hypothesis

• When in solution molecules move about
• When an enzyme molecule collides with its
  substrate molecule the substrate binds to the
  enzymes active site
• Together they form an enzyme-substrate complex

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The lock and key mechanism
Active Site
Substrate
Enzyme
The weak bonds between the substrate and the
enzyme require energy, which is provided by the
bonds in the substrate.
Enzyme-substrate complex
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Catabolism

• Water then moves between the bonds in the
  substrate to break them

Which forms...
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The Product
The product then leaves the active site as the
bonds are sufficiently weakened
The enzyme returns to its original form ready to
react with the substrate again