ENDOCRINE DISRUPTORS RESEARCH PROGRAM:

1
ENDOCRINE DISRUPTORS RESEARCH PROGRAM MATERIAL
OVERVIEW
Elaine Francis National Program Director,
Pesticides and Toxics Research
EDCs Research Program Mid-Cycle BOSC Review
August 21, 2007
2
Technical Background Materials(In Notebook) - 1

• Draft charge (Tab C)
• Outlines purpose, background, and charge
  questions
• List of available materials (Tab E)
• Some are copied into reviewers notebooks or will
  be sent in a second mailing
• Additional background materials include
• Research Plan for Endocrine Disruptors
  (www.epa.gov/ord/htm/documents/ORD-EDR-Feb1998.pdf
  )
• Previous Multi-Year Plan for Endocrine Disruptors
  (2003) (www.epa.gov/osp/myp/edc.pdf)
• Computational Toxicology Research Framework
  (www.epa.gov/comptox/publications/comptoxframework
  06_02_04.pdf)
• Safe Pesticides/Safe Products Multi-Year Plan
  (www.epa.gov/osp/myp/sp2.pdf)

3
Technical Background Materials (In Notebook) - 2

• Bibliography (Tab K)
• Lists all of the peer reviewed publications from
  the EDCs research program by Long Term Goal and
  identifies the Laboratory/Center of the principal
  investigators
• Publications from 2004 (i.e., last BOSC review)
  are in red
• Report from previous BOSC review and ORD Response
  
• BOSC report April 2005 (Tab F)
• ORD response (narrative and table)
  September 2005 (Tab G)

4
Technical Background Materials (In Next Mailing)

• Progress Report (Tab I)
• Summarizes progress made regarding ORD
  commitments in its response to BOSC
  recommendations from the previous review
• Updated Multi-Year Plan (Tab H)
• Working draft
• Synthesis document (Tab J)
• Draft of a summary of intramural and STAR
  extramural research in three areas
• screening and testing assay development,
• impacts of developmental exposures, and
• exposures and effects on wildlife

5
Performance Rating Materials (In Notebooks)

• Program Performance Measures and Goals (Tab L)
• Identifies the Long Term Outcomes agreed upon
  with OMB (in 2004 PART review) for which the 2009
  BOSC review will rate the research program
• Identifies Annual Outputs reported to OMB that
  are planned vs. those that are met (actual)
  since 2001
• Annual Performance Goals (Tab L)
• Outlines the programs success in meeting its
  planned APGs on time
• Bibliometric Analysis (Tab M)
• Analysis of quality and impact of ORD peer
  reviewed publications reflects high citation and
  high impact journal publication rates, among
  other parameters