DNARNA

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DNA/RNA

• Kenita Jackson
• Harmita Modi
• Melanie Thomas

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DNA/RNA

• All living organisms and some viruses contains
  genetic material DNA in the nucleus
• Some viruses contains genetic material RNA in the
  nucleus
• Deoxyribonucleic acid is the molecule that stores
  the genetic information of living organisms
• Ribonucleic acid is the molecule that relays the
  genetic information of DNA

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Nucleotides

• Deoxyribonucleic acid This molecule consist of
  polymers of deoxyribose sugar-phosphate with
  nitrogen bases consisting of Adenine,Guanine,
  Thymine, and Cytosine.

• Ribonucleic acid This molecule consist of
  polymers of ribose sugar-phosphate base with
  nitrogen bases of Adenine, Guanine, Cytosine, and
  Uracil.

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Base pairing A,G-PURINES C,T,U-PYRIMIDINES
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Structures

• DNA is double stranded
• G-C pairs have 3 hydrogen bonds
• A-T pairs have 2 hydrogen bonds
• One strand is the complement of the other
• Major and minor grooves between backbones
• Each base pairs are 0.34nm
• Per turn- 10 base pairs

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RNA structure

• Ribose
• Bases include adenine,cytosine, guanine, and
  uracil
• OH on the second carbon atom

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• RNA can be single or double stranded
• G-C pairs have 3 hydrogen bonds
• A-U pairs have 2 hydrogen bonds
• Single-stranded, double-stranded, and loop RNA

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DNA orientation

• Characterisically consists of two polynucleotide
  strands wound together form a long slender
  helical molecule
• Antiparallel chains
• 5-3 3-5 directions
• Sugar-phosphate backbone outside
• Base pairs in middle

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• RNA is single stranded
• 5-3
• usually contain regions where two portions of the
  strand twist around each other to form helical
  regions.
• Complementary bases of 4 stem are paired up with
  hydrogen bond
• 3 end amino acid attaches
• m-RNA codon lines up with the anticodon region

users.rcn.com/.../N/Nucleotides.html
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Genetic material

• DNA is in nucleus of the cell, except for that
  its in the mitochondria
• In mitochondria DNA is still double helix but it
  loops around, in nucleus of the cell its not
  looped

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Bibliography

• Cox, M. and Nelson, D. 2005. Lehninger Principles
  of Biochemistry,4th edition. Freeman.
• Russel, P. 2003. Essential iGenetics. Benjamin
  Cummings.
• Newman, T.J. 2005. http//phy.asu.edu/phy598-bio/D
  320Notes2006.htm.
• Secko, D. 2003. http//www.scq.ubc.ca/a-monks-flou
  rishing-garden-the-basics-of-molecular-biology-exp
  lained/.