Enhanced surveillance of acute HIV infection in inner Sydney

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Enhanced surveillance of acute HIV infection in
inner Sydney

• St Vincents Hospital reference laboratory
  diagnoses 60-70 of NSW cases of HIV (30
  Australia)
• 75 of newly identified cases of HIV are from
  high HIV case load primary care sites
• Laboratory testing strategy is focused on
  detection of acute HIV
• Direct detection of HIV by antigen or NAT
  routinely used in cases with clinical suspicion
  of PHI
• Proposed to test pools of HIV-1/2 Ab/Ag
  non-reactive samples for presence of HIV-1 RNA
  to identify acute cases of primary HIV infection
• Potential applications for surveillance, early
  clinical intervention, possible prevention of
  secondary HIV transmission

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