Toxicogenomics and Toxicogenetics Maastricht University J. van Delft, D. van Leeuwen, H. Ketelslegers, R. Vlietinck, J. Kleinjans General concept Goals Development ...
... in adult and neonatal rodents; human exposures are similar in ... Only ~2,000 of 70,000 chemicals in commerce have been tested in rodent chronic bioassay ' ...
Any biologically active material originating from outside of the body ... Classical Pharmacogenetics: enzymology, biochemistry and population genetics ...
Chapter 9 Biotransformation Biotransformation The term biotransformation is the sum of all chemical processes of the body that modify endogenous or exogenous chemicals.
Only ~2,000 of 70,000 chemicals in commerce have been tested in rodent chronic bioassay ' ... Chemical C causes cancer only at high doses in rodents. ...