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Bioorg - Bioorg nica y Qu mica Medicinal Introducci n a la Qu mica Medicinal Or genes de la Qu mica Medicinal. Principios del descubrimiento de f rmacos.

Bioorg nica y Qu mica Medicinal Introducci n a la Qu mica Medicinal Or genes de la Qu mica Medicinal. Principios del descubrimiento de f rmacos.

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Factora de Talento Presentacin MACC 23042009 PowerPoint PPT Presentation

Factora de Talento Presentacin MACC 23042009 - ... de captaci n: Creative Hunter/ Otros (T4) BioOrg: Gen tica ... EQUIPO CREATIVE HUNTERS. Perfil multidisciplinar y experto en nuevas tecnolog as y contenido ...

... de captaci n: Creative Hunter/ Otros (T4) BioOrg: Gen tica ... EQUIPO CREATIVE HUNTERS. Perfil multidisciplinar y experto en nuevas tecnolog as y contenido ...

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Recent Publications and Presentations: PowerPoint PPT Presentation

Recent Publications and Presentations: - Recent Publications and Presentations: Brown, T; et al.; 2006, Bioorg. Med. Chem. ... Ph. D. Related Publications and Presentations: ...

Recent Publications and Presentations: Brown, T; et al.; 2006, Bioorg. Med. Chem. ... Ph. D. Related Publications and Presentations: ...

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?????:????????????,???1876??Chemical Reviews(Chem. Rev. ) PowerPoint PPT Presentation

?????:????????????,???1876??Chemical Reviews(Chem. Rev. ) - 1 ...

1 ...

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The Efficacy of Synthetic Steroids to Inhibit Hormonal Receptors PowerPoint PPT Presentation

The Efficacy of Synthetic Steroids to Inhibit Hormonal Receptors - Prostate Cancer -has the greatest incidence of death ... Cancer treatment ... toward androgen receptor mutants that can emerge in advanced prostate cancer' ...

Prostate Cancer -has the greatest incidence of death ... Cancer treatment ... toward androgen receptor mutants that can emerge in advanced prostate cancer' ...

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Novel Acyclic Enediynes Inhibit Cyclin A and Cdc25C Expression and PowerPoint PPT Presentation

Novel Acyclic Enediynes Inhibit Cyclin A and Cdc25C Expression and - Induce Apoptosis Phenomenon to Show Potent Antitumor Proliferation ... 2. Kim, K. S.; Sack, J. S.; Tokarski, J. S.; Qian, L.; Chao, S. T.; Leith, L.; Kelly, Y. F. ...

Induce Apoptosis Phenomenon to Show Potent Antitumor Proliferation ... 2. Kim, K. S.; Sack, J. S.; Tokarski, J. S.; Qian, L.; Chao, S. T.; Leith, L.; Kelly, Y. F. ...

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Sulfur Compounds in Organic Synthesis PowerPoint PPT Presentation

Sulfur Compounds in Organic Synthesis - R3S Br , RS(=O)R', RS(=O)OR', etc ... Using the natural nucleophilicity of indoles. Slide 21. Divalent Sulfur. Electrophilic sulfur ...

R3S Br , RS(=O)R', RS(=O)OR', etc ... Using the natural nucleophilicity of indoles. Slide 21. Divalent Sulfur. Electrophilic sulfur ...

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PHEROMONES AND SEMIOCHEMICALS IN ANIMAL COMMUNICATION : OVERVIEW AND CHEMISTRY PowerPoint PPT Presentation

PHEROMONES AND SEMIOCHEMICALS IN ANIMAL COMMUNICATION : OVERVIEW AND CHEMISTRY - PHEROMONES AND SEMIOCHEMICALS IN ANIMAL COMMUNICATION : OVERVIEW AND CHEMISTRY Thibaut Denoel Department of Chemistry Cyclotron Research Center (CRC)

PHEROMONES AND SEMIOCHEMICALS IN ANIMAL COMMUNICATION : OVERVIEW AND CHEMISTRY Thibaut Denoel Department of Chemistry Cyclotron Research Center (CRC)

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Continued from part a PowerPoint PPT Presentation

Continued from part a - ... theory / Biomolecules ... UIC FT-VCD Schematic (designed for magnetic VCD commercial ones simpler) Electronics Optics FTIR Separate VCD Bench Polarizer PEM ...

... theory / Biomolecules ... UIC FT-VCD Schematic (designed for magnetic VCD commercial ones simpler) Electronics Optics FTIR Separate VCD Bench Polarizer PEM ...

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Diapositiva 1 PowerPoint PPT Presentation

Diapositiva 1 - Title: Diapositiva 1 Author: Giovanni Tosi Last modified by: CIGS Created Date: 5/14/2005 2:40:08 PM Document presentation format: Presentazione su schermo

Title: Diapositiva 1 Author: Giovanni Tosi Last modified by: CIGS Created Date: 5/14/2005 2:40:08 PM Document presentation format: Presentazione su schermo

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Lead hopping and focused library design applied to the synthesis of activators of the nitric oxide s PowerPoint PPT Presentation

Lead hopping and focused library design applied to the synthesis of activators of the nitric oxide s - Lead hopping and focused library design applied to the synthesis of ... 5HT1B 5HT1D Agonism (5HT is 1.0) 6.95 7.80 0.09. 4991. Went through phase 2 development ...

Lead hopping and focused library design applied to the synthesis of ... 5HT1B 5HT1D Agonism (5HT is 1.0) 6.95 7.80 0.09. 4991. Went through phase 2 development ...

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Diapositiva 1 - Oficinas e instalaciones ubicadas en el Pol gono Poliviso, Av. ... Antioxidants, Extracts. Pevesa AminoFarma R. Pevesa AminoFarma S. Pevesa AminoFarma OR ...

Oficinas e instalaciones ubicadas en el Pol gono Poliviso, Av. ... Antioxidants, Extracts. Pevesa AminoFarma R. Pevesa AminoFarma S. Pevesa AminoFarma OR ...

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Recent Advances in Antifungal Drug Development PowerPoint PPT Presentation

Recent Advances in Antifungal Drug Development - Recent Advances in Antifungal Drug Development Jennifer O Neill February 2, 2006 Dramatic Increase 300% as many hospital-acquired fungal infections Increase in ...

Recent Advances in Antifungal Drug Development Jennifer O Neill February 2, 2006 Dramatic Increase 300% as many hospital-acquired fungal infections Increase in ...

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Zedoary-Induced Cardiovascular Disorders PowerPoint PPT Presentation

Zedoary-Induced Cardiovascular Disorders - In this case report, two young adult female patients with cardiovascular disorders (hypotension and bradyarrhythmias), caused by ingestion of an extract of Zedoary (overdose) were described. The most patient clinical issues were discussed.

In this case report, two young adult female patients with cardiovascular disorders (hypotension and bradyarrhythmias), caused by ingestion of an extract of Zedoary (overdose) were described. The most patient clinical issues were discussed.

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Nucleic acid aptamers PowerPoint PPT Presentation

Nucleic acid aptamers - Nucleic acid aptamers Aptamers: molecules that bind other molecules with good affinity and specificity Usually these are proteins . . . . But they can also be RNA or DNA.

Nucleic acid aptamers Aptamers: molecules that bind other molecules with good affinity and specificity Usually these are proteins . . . . But they can also be RNA or DNA.

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JIC Granada - poster presentation

poster presentation

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TREATMENT OF VIRAL RESPIRATORY INFECTIONS PowerPoint PPT Presentation

TREATMENT OF VIRAL RESPIRATORY INFECTIONS - Title: Respiratory virus inhibitors Author: kuleuven Last modified by: Paul M. Tulkens Created Date: 1/16/2003 9:12:43 PM Document presentation format

Title: Respiratory virus inhibitors Author: kuleuven Last modified by: Paul M. Tulkens Created Date: 1/16/2003 9:12:43 PM Document presentation format

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Regulation of Gene Expression PowerPoint PPT Presentation

Regulation of Gene Expression - In principle, every step required for the process of gene expression could ... Grate D, Wilson C.Inducible regulation of the S. cerevisiae cell cycle mediated ...

In principle, every step required for the process of gene expression could ... Grate D, Wilson C.Inducible regulation of the S. cerevisiae cell cycle mediated ...

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Detection of the pharmaceutical agent PowerPoint PPT Presentation

Detection of the pharmaceutical agent - Detection of the pharmaceutical agent Glaucine as a recreational drug Analytical Unit St Georges - University of London, London, UK1 Guy s and St Thomas ...

Detection of the pharmaceutical agent Glaucine as a recreational drug Analytical Unit St Georges - University of London, London, UK1 Guy s and St Thomas ...

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Talent Factory PowerPoint PPT Presentation

Talent Factory - We position in R D I in advanced digital content. We aim to be an approved ... Microcomputing 45 working places electronics storage closets 330.176 ...

We position in R D I in advanced digital content. We aim to be an approved ... Microcomputing 45 working places electronics storage closets 330.176 ...

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Olefin Cross Metathesis PowerPoint PPT Presentation

Olefin Cross Metathesis - ... acrylamides, acrylic acid, acrolein, vinyl ketones vinyl epoxides perfluorinated alkane olefins styrenes (large ortho substituents) ...

... acrylamides, acrylic acid, acrolein, vinyl ketones vinyl epoxides perfluorinated alkane olefins styrenes (large ortho substituents) ...

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Iminosugars : Their Synthesis and Therapeutic Applications for Gaucher disease PowerPoint PPT Presentation

Iminosugars : Their Synthesis and Therapeutic Applications for Gaucher disease - Iminosugars : Their Synthesis and Therapeutic Applications for Gaucher disease Presentation of the Compain Group Achievements (Universit de Strasbourg, France)

Iminosugars : Their Synthesis and Therapeutic Applications for Gaucher disease Presentation of the Compain Group Achievements (Universit de Strasbourg, France)

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Environmental Risks Factors in ASD: What We Know What We Need to Know PowerPoint PPT Presentation

Environmental Risks Factors in ASD: What We Know What We Need to Know - Are children genetically predisposed to autism's ... A common mechanism for autism susceptibility may stem from abnormal ratios of ...

Are children genetically predisposed to autism's ... A common mechanism for autism susceptibility may stem from abnormal ratios of ...

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FIOCRUZ - ... pelos anos 1910-12 e teve sua constru o conclu da um ano ap s sua morte. Instituto Nacional de Controle de Qualidade em Sa de.

... pelos anos 1910-12 e teve sua constru o conclu da um ano ap s sua morte. Instituto Nacional de Controle de Qualidade em Sa de.

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From distamycin to brostallicin : a case history PowerPoint PPT Presentation

From distamycin to brostallicin : a case history - Lack of selectivity, leading to toxicity ... affinity and selectivity of interaction with ... a DNA sequence-selective vector. New distamycin-derived mustards ...

Lack of selectivity, leading to toxicity ... affinity and selectivity of interaction with ... a DNA sequence-selective vector. New distamycin-derived mustards ...

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Syntheses and Structures of Tungsten(0) Complexes of Tris(2-pyridylmethyl)amine and The Catalytic Applications to Biginelli Condensation Reactions - ... Optimized Conditions for Neat Systems The Optimized Conditions for Thiourea/Ethanol System The Optimized Conditions for Thiourea/DMF System Multicomponent ...

... Optimized Conditions for Neat Systems The Optimized Conditions for Thiourea/Ethanol System The Optimized Conditions for Thiourea/DMF System Multicomponent ...

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Quantitative proteomics - ICAT PowerPoint PPT Presentation

Quantitative proteomics - ICAT - Quantitative proteomics - ICAT a The identification and quantitation of complex protein mixtures have been facilitated by MS-based quantitative proteomic techniques.

Quantitative proteomics - ICAT a The identification and quantitation of complex protein mixtures have been facilitated by MS-based quantitative proteomic techniques.

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12103 11:01 PM PowerPoint PPT Presentation

12103 11:01 PM - Inverted T at 3' end (3'-3') slows exonucleolytic degradation ( R-3' ... Is marketed for adult macular degeneration (wet type) From the label: Inverted ribo-T ...

Inverted T at 3' end (3'-3') slows exonucleolytic degradation ( R-3' ... Is marketed for adult macular degeneration (wet type) From the label: Inverted ribo-T ...

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In silico ADME modelling 2: Computational models to predict human serum albumin binding affinity usi PowerPoint PPT Presentation

In silico ADME modelling 2: Computational models to predict human serum albumin binding affinity usi - In silico ADME modelling 2: Computational models to predict human serum albumin ... Atomic Type Electro-topological state index describing hydrophobicity ...

In silico ADME modelling 2: Computational models to predict human serum albumin ... Atomic Type Electro-topological state index describing hydrophobicity ...

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Many human genetic diseases are caused by mutations causing missplicing PowerPoint PPT Presentation

Many human genetic diseases are caused by mutations causing missplicing - Alternative 5' splicing. Unwanted = longer exon. Antisense shorter isoform ... B. Bias alternative splicing ratios. Target the unwanted isoform exon-intron joint. ...

Alternative 5' splicing. Unwanted = longer exon. Antisense shorter isoform ... B. Bias alternative splicing ratios. Target the unwanted isoform exon-intron joint. ...

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Dr' Andrew Stachulski PowerPoint PPT Presentation

Dr' Andrew Stachulski - A human metabolite of morphine at least as potent an analgesic ... The 17-formate was prepared by ester exchange (HCO2Et,Tos-OH, distil) ...

A human metabolite of morphine at least as potent an analgesic ... The 17-formate was prepared by ester exchange (HCO2Et,Tos-OH, distil) ...

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TREATMENT OF VIRAL RESPIRATORY INFECTIONS - Influenza viruses: Influenza (upper and lower respiratory tract infections) ... fruit bats (flying foxes) ? Clinical hosts : horse, pig, man,... Experimental hosts : ...

Influenza viruses: Influenza (upper and lower respiratory tract infections) ... fruit bats (flying foxes) ? Clinical hosts : horse, pig, man,... Experimental hosts : ...

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AAPS Workshop on Optimization of DrugLike Properties During Lead Optimization PowerPoint PPT Presentation

AAPS Workshop on Optimization of DrugLike Properties During Lead Optimization - Exploratory Confirmed Hits (1000s) to Advanced Hits (4-7) ... Rachel Garlish. Hanlan Liu. Chantel Sabus. Computational Chemistry/X-Ray. Diane Joseph-McCarthy ...

Exploratory Confirmed Hits (1000s) to Advanced Hits (4-7) ... Rachel Garlish. Hanlan Liu. Chantel Sabus. Computational Chemistry/X-Ray. Diane Joseph-McCarthy ...

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Introduction to Bioinformatics 20120 PowerPoint PPT Presentation

Introduction to Bioinformatics 20120 - Schoenfeld,J., Seshagiri,S., Simmons,L., Singh,J., Smith,V. ... gene='SFTPG' ORIGIN. 1 ggggtgtaga aacaggcctg ttaaggagag gccaccggga cttcagtgtc tcctccatcc ...

Schoenfeld,J., Seshagiri,S., Simmons,L., Singh,J., Smith,V. ... gene='SFTPG' ORIGIN. 1 ggggtgtaga aacaggcctg ttaaggagag gccaccggga cttcagtgtc tcctccatcc ...

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Cisplatin - Medicinal Inorganic Chemistry Outline Medicinal Inorganic chemistry: Essential Elements Medicinal Inorganic chemistry: Chelation Therapy Medicinal Inorganic chemistry ...

Medicinal Inorganic Chemistry Outline Medicinal Inorganic chemistry: Essential Elements Medicinal Inorganic chemistry: Chelation Therapy Medicinal Inorganic chemistry ...

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Synthesis of Lamellarin D PowerPoint PPT Presentation

Synthesis of Lamellarin D - Normal cells-- new cell growth balance with old cells die ... from ascidian and sponge species * A pentacyclic core, variation from ...

Normal cells-- new cell growth balance with old cells die ... from ascidian and sponge species * A pentacyclic core, variation from ...

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Learning to Express and Purify Mammalian Proteins - Learning to Express and Purify Mammalian Proteins

Learning to Express and Purify Mammalian Proteins

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The hostmicrobe interphase as a target for antiinfective therapy PowerPoint PPT Presentation

The hostmicrobe interphase as a target for antiinfective therapy - Most bacteria must first adhere to host cell surfaces to cause infection ... Bis(indol)alkaloid isolated from marine sponge Spongosorites sp. ...

Most bacteria must first adhere to host cell surfaces to cause infection ... Bis(indol)alkaloid isolated from marine sponge Spongosorites sp. ...

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Discovery of SCH 530348 A Thrombin Receptor Antagonist TRA with Potent Antiplatelet Activity Samuel PowerPoint PPT Presentation

Discovery of SCH 530348 A Thrombin Receptor Antagonist TRA with Potent Antiplatelet Activity Samuel - Excellent oral activity in c. monkeys (ex-vivo) ... (Major Adverse Cardiac Event): Death, MI, ischemia requiring rehospitalization, ...

Excellent oral activity in c. monkeys (ex-vivo) ... (Major Adverse Cardiac Event): Death, MI, ischemia requiring rehospitalization, ...

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Continued from part a - Relationship to 'random coil' - compare Pron and Glun ... That is all for now. Good luck on exams. I enjoyed having you in class this Fall. Tim Keiderling ...

Relationship to 'random coil' - compare Pron and Glun ... That is all for now. Good luck on exams. I enjoyed having you in class this Fall. Tim Keiderling ...

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Metabolic Activation and Idiosycratic Drug Toxicity: By Avoiding Structural Alerts, Do We Mitigate Risks? PowerPoint PPT Presentation

Metabolic Activation and Idiosycratic Drug Toxicity: By Avoiding Structural Alerts, Do We Mitigate Risks? - Metabolic Activation and Idiosycratic Drug Toxicity: By Avoiding Structural Alerts, Do We Mitigate Risks? Amit S. Kalgutkar, Ph.D. Pfizer Global Research and Development

Metabolic Activation and Idiosycratic Drug Toxicity: By Avoiding Structural Alerts, Do We Mitigate Risks? Amit S. Kalgutkar, Ph.D. Pfizer Global Research and Development

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DOUBLE WHAMMY: Is there a common switch to avoid anticancer drugs PowerPoint PPT Presentation

DOUBLE WHAMMY: Is there a common switch to avoid anticancer drugs - Be able to explain how this leads to Multidrug Resistance ... 3) Starling JJ, Shepard RL, Cao J, et al. Pharmacological characterization of ...

Be able to explain how this leads to Multidrug Resistance ... 3) Starling JJ, Shepard RL, Cao J, et al. Pharmacological characterization of ...

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Agriculture's influence on native grassland microflora Amy Vaira PowerPoint PPT Presentation

Agriculture's influence on native grassland microflora Amy Vaira - ... Mikola, C. Robin, H. Setala, F. Tatin-Froux, W.H. Van der Putten, and S. Scheu. ... 6. Garbeva, P., J.A. Van Veen, and J.D. Van Elsas. 2004. ...

... Mikola, C. Robin, H. Setala, F. Tatin-Froux, W.H. Van der Putten, and S. Scheu. ... 6. Garbeva, P., J.A. Van Veen, and J.D. Van Elsas. 2004. ...

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A novel and convenient method for the synthesis of free 5thiol modified oligonucleotides PowerPoint PPT Presentation

A novel and convenient method for the synthesis of free 5thiol modified oligonucleotides - ... Mixed Poly-PakTM and thiol-sepharose (as immobilized scavenger) 1:1 m/m ... DTT (used for activating the sepharose-linked thiol scavenger) impurities in product ...

... Mixed Poly-PakTM and thiol-sepharose (as immobilized scavenger) 1:1 m/m ... DTT (used for activating the sepharose-linked thiol scavenger) impurities in product ...

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Oligomerization of b-Cleft Cross-Linked Human Hemoglobin: Synthesis, Intramolecular Cross-linking, and Intermolecular Coupling Studies with Polyfunctional Organic Reagents - Oligomerization of bCleft CrossLinked Human Hemoglobin: Synthesis, Intramolecular Crosslinking, and

Oligomerization of bCleft CrossLinked Human Hemoglobin: Synthesis, Intramolecular Crosslinking, and

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BIO2009 Federal Science and Opportunities Track PowerPoint PPT Presentation

BIO2009 Federal Science and Opportunities Track - Peptides/Proteins Nucleic Acids/Vectors Assays Small Molecules Animal Models Antibodies Cell Lines Libraries ... heart disease, cancer, hepatitis, and autoimmune ...

Peptides/Proteins Nucleic Acids/Vectors Assays Small Molecules Animal Models Antibodies Cell Lines Libraries ... heart disease, cancer, hepatitis, and autoimmune ...

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Structural Insights into Kinase Inhibition Ramesh Sistla and Subramanya H'S' Aurigene Discovery Tech PowerPoint PPT Presentation

Structural Insights into Kinase Inhibition Ramesh Sistla and Subramanya H'S' Aurigene Discovery Tech - Human genome encodes 500 kinases - Kinome ... Adenosine moiety of the ATP makes bidentate H-bond with this region. Activation loop ...

Human genome encodes 500 kinases - Kinome ... Adenosine moiety of the ATP makes bidentate H-bond with this region. Activation loop ...

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BIO2009 Federal Science and Opportunities Track - ... research being conducted at Federal laboratories in the field of Biotechnology ... Hot Federal Biotechnologies Available for Collaboration and Licensing ...

... research being conducted at Federal laboratories in the field of Biotechnology ... Hot Federal Biotechnologies Available for Collaboration and Licensing ...

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In Vitro Activities of Piperacillin in Combination with the Penem - ... use of third generation cephalosporin antibacterial agents has resulted in ... most effective fourth generation cephalosporin, has been associated with ...

... use of third generation cephalosporin antibacterial agents has resulted in ... most effective fourth generation cephalosporin, has been associated with ...

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1. dia - aCooperative Research Centre, Semmelweis University, Rippl-R nai u. ... Valerie G. Brunton; Martin J. Lear; David J. Robins; Sharon Williamson; Paul Workman. ...

aCooperative Research Centre, Semmelweis University, Rippl-R nai u. ... Valerie G. Brunton; Martin J. Lear; David J. Robins; Sharon Williamson; Paul Workman. ...

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InsulinMimetic Activity of Unnatural IPGs PowerPoint PPT Presentation

InsulinMimetic Activity of Unnatural IPGs - Insulin signaling at the target tissue is complex, involving a cell surface ... h: NaH, AllBr, DMF, 0 oC to rt, 2hr; j: LiOH, H2O, THF; k:Cl3CCN, K2CO3; l: ...

Insulin signaling at the target tissue is complex, involving a cell surface ... h: NaH, AllBr, DMF, 0 oC to rt, 2hr; j: LiOH, H2O, THF; k:Cl3CCN, K2CO3; l: ...

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A number of compounds from marine algae have been reported to have antitumour and cytotoxic properties. Ma PowerPoint PPT Presentation

A number of compounds from marine algae have been reported to have antitumour and cytotoxic properties. Ma - CYTOTOXIC COMPOUNDS FROM BRITISH MARINE ALGAE G. BLUNDEN1, N. A. S. SHOEIB2, 3 and C. W. WRIGHT2 1School of Pharmacy, University of Portsmouth, Portsmouth, P01 ...

CYTOTOXIC COMPOUNDS FROM BRITISH MARINE ALGAE G. BLUNDEN1, N. A. S. SHOEIB2, 3 and C. W. WRIGHT2 1School of Pharmacy, University of Portsmouth, Portsmouth, P01 ...

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