Paul%20Rothemund - PowerPoint PPT Presentation

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Paul%20Rothemund

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Paul Rothemund s Scaffolded DNA Origami Method DNA Origami Scaffolded DNA Origami DNA Origami Folding Process M13 viral genome DNA & Staple Stands Self-assembles ... – PowerPoint PPT presentation

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Title: Paul%20Rothemund


1
Paul Rothemunds Scaffolded DNA Origami Method
2
DNA Origami
3
Scaffolded DNA Origami
Paul Rothemund Folding DNA to create nanoscale
shapes and patterns Nature, 440297-302 (2006).
4
DNA Origami Folding Process
  • M13 viral genome DNA Staple Stands
  • Self-assembles into designed structure

5
Staple crossover
6
Surface patterns with hairpin loops
Staple without hairpin loop
Staple with hairpin loop
7
Hairpin becomes a pixel on origami surface
Staple Hairpin (yellow)
Staple (blue)
Scaffold (red)
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