Global Burden of Mental disorders

1
Global Burden of Mental disorders

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  (???????????)
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2
DALY (Disability-Adjusted Life Year)
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1 DALY ???????????????????????????????????????
?????????? 1 ??
3
DALY YLL YLD
YLL N X L N ??????????? L
???????????????????? YLD I X DW X L I
??????????????????????????????????????? DW
disability weights L ???????????????????????
?????????????(??)
4
Mental disorders

• Major Depressive disorder
• Bipolar disorder
• Schizophrenia
• Anxiety disorders
• 4.1 Panic disorder
• 4.2 Agoraphobia
• 4.3 Generalize anxiety disorder
• Alcohol dependence/harmful use
• Drug dependence/harmful use

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Bipolar Disorder
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Case and sequelae definitions for bipolar disorder
The case definition for bipolar disorder is based
on the ICD-10 criteria. The case definition and
sequelae used for bipolar disorder are given in
Table below.
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Disability weights and health state descriptions
in GBD 2000
???????????? ??????????? ??????????Treated
Untreated ?????? 5050 or 6040
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Prevalence of Bipolar disorder data sources
- summary
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prevalence and incidence studiesOf mood disorders

• Waraich P, Goldner EM,Somers JM, Hsu L.
  prevalence and incidence studies Of mood
  disorders systematic review of literature. Can J
  Psy.2004,Feb49(2)124-138
• Pool rate of 1 year prevalence
• Major depressive disorder 4.1 per100
• Dysthymia 2.0 per100
• Bipolar I disorder 0.72 per100

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Disease model assumptions of Bipolar disorder
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Disease model assumptions of Bipolar disorder
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DisMod result Bipolar
13
DisMod result Bipolar
14
???????????????????? Bipolar disorder
Population without Disorders
Death from other causes
1
4
5
6
Incidence
Remission
7
Mortality
10
Population with Bipolar Disorder
Death from Suicide
3
8
Untreated Bipolar Disorder
2
9
Population with Bipolar Disorder Anxiety disorder
11
12
13
14
15
???????????????????? Bipolar disorder
Population without Disorders
Death from other causes
1
4
5
6
Incidence
Remission
7
Mortality
10
Population with Bipolar Disorder
Death from Suicide
3
8
Untreated Bipolar Disorder
11
Coronary Heart disease
Death from Heart attack
2
9
12
Population with Bipolar Disorder Anxiety disorder
13
14
15
16
17
16
Panic Disorder
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Case and sequelae definitions for panic disorder
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Disability weights and health state descriptions
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Disease model assumptions of Panic disorder
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Disease model assumptions of Panic disorder
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Generalize Anxiety Disorder
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Case and sequelae definitions for GAD
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Disability weights and health state descriptions
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Disease model assumptions of GAD
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Disease model assumptions of GAD
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Major depressive Disorder And Dysthymic Disorder

• MDD by SPICE

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Case and sequelae definitions for unipolar
depressive disorders and Dysthymic disorder
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Disability weights and health state descriptions
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Disease model assumptions of Major depressive
disorder
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Disease model assumptions of Major depressive
disorder
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Disease model assumptions of Dysthymia
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Disease model assumptions of Dysthymia
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Schizophrenia

• SPICE

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Case and sequelae definitions for schizophrenia
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Disability weights and health state descriptions
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Disease model assumptions of Shizophrenia
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Disease model assumptions of Shizophrenia
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Prevalence of Mental Disorders from National
Mental Health Survey 2003
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Data from NMHS 2003 Thai
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Data from NMHS 2003 Thai
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?????????????????????????????????????? DisMod