Title: Brain Scintigraphy
1Brain Scintigraphy
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6Brain Scintigraphy
Normals Effects of Color Maps
7Kansas University
Brain Scintigraphy
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Decreased perfusion right side large CVA
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Decreased activity on contralateral cerebellum
Cross cerebellar dischisis
13Brain Scintigraphy
Luxury perfusion
Occurs when there is increased blood flow and
reduced O2 in brain tissue. Causes acute
lactic-metabolic acidosis. Many
different disease states can cause this CVA,
trauma, tumor, etc.
14Brain Scintigraphy
Diamoix HMPAO MRI Harvard
Ischemia
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Diamoix HMPAO
Ischemia
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Central area of infarction with regional
ischemia.
Revascularization?
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Central area of infarction with regional
ischemia.
Revascularization?
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Transverse Slices Tc99m HMPAO
Normal
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Transverse Slices Tc99m HMPAO
Globally decreased function (particularly
pariatal lobes) /decreased gray mater
Alzheimer's Disease
20Brain Scintigraphy
Transverse Slices Tc99m HMPAO Alzheimer's Disease
Transverse Slices Tc99m HMPAO Normal
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Coronal Slices Tc99m HMPAO Alzheimer's Disease
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Sagittal Slices Tc99m HMPAO Alzheimer's Disease
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Patchy diffuse areas of increased and decreased
activity
Differential diagnosis Multi-infarct
Dementia Cocaine Abuse
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Initial scan Diagnosis Cocaine abuse
6 month follow-up
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Brain Multi-infact Transverse
26Brain Scintigraphy
Increased perfusion to temporal lobe.
Herpes Encephalitis
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melenoma MRI.1t2
Tl201
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MRI / Tl201 Overlay Harvard
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Melanoma HMPAO
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MRI
Tl201
HMPAO
Melanoma
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Melanoma HMPAO MRI Overlay
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Glioblastoma
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Tl Brain SPECT Previous Radiation for Glioblastoma
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48 hours Mallincrodt
Slow movement over convexities
Activity in lateral ventricles
NPH
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Delayed movement over convexities at 48 hours.
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Delayed movement over convexities at 48 hours.
LEAP on posterior
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Same patient with laterals
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4 hour
24 hour
48 hour
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Shunt Patency
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Non-patient Shunt
At 20 minutes following injection of tracer into
the shunt reservoir, activity is seen in the
proximal limb tubing only. At 40 minutes,
activity is seen in the lateral ventricles, and
third and fourth ventricles, as well as extending
down the spinal canal. Still, no activity is seen
in the distal shunt.
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Occluded Shunt?
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Abdominal Images
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Displaying the initial images at higher intensity
allows visualization of tiny lymphatic channels
draining activity away from an infiltrated dose
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Flow study
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Flow for brain death
48Brain Scintigraphy
Is this Brain Death?
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