Title: Cytology Weekly Cases
1Cytopathology Challenge! Weekly Cases
March 13, 2009
2Lymphocytes mixed with follicular cells.
28 y/o female. FNA of thyroid.
Hashimotos thyroiditis
1
338 year old male, BAL.
Goblet cell hyperplasia. Associated with asthma,
chronic bronchitis, bronchiectasis, and
allergies.
2
468 year old male, bile duct brushing.
Adenocarcinoma. Disordered arrangement of
slightly enlarged and pleomorphic cells. Normal
ductal cells are arranged in a honeycomb pattern.
3
565 y/o male. FNA of liver
HCC. Large, pleomorphic liver cells with
prominent nucleoli. HCC also has intranuclear
pseudoinclusion.
4
6Pancreas FNA.
Mucinous papillary ca
5
7FNA of kidney.
Renal cell ca. The clear cytoplasm is
characteristic.
6
8FNA of spleen.
Extramedullary hematopoiesis. The large cell is a
megakaryocyte.
7
9Subcarinal LN FNA.
Small cell ca. The typical findings are cells
with high NC ratios, molding, mitotic activity,
and necrosis. Differentiate from lymphocytes by
cohesion.
8
10Thyroid FNA
Hürthle cell neoplasm. Abundant cytoplasm and
prominent nucleoli. Cannot tell the difference
between Hürthle call adenoma or carcinoma on
cytology.
9
11Thyroid FNA.
Papillary ca. Cells with large nuclei, fine
chromatin, nuclear cleaves, small peripheral
nucleoli, and nuclear pseudoinclusions.
10