CONTACT NUMBERS

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DR. RAJ LAKSHMANPROFESSOR OF BIOCHEMISTRY,
MOLECULAR BIOLOGY MEDICINE

• CONTACT NUMBERS
• TEL[phone]
• FAX [phone]
• EMAIL RAJ.LAKSHMAN_at_MED.VA.GOV

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DR. LAKSHMANS  FUNDINGNIH GRANTS

• Mechanisms of Actions of Alcohol Omega3-Fatty
  Acids.
• To delineate the mechanisms of actions of alcohol
  and omega3-fatty acids in altering the
  post-translational modifications of glycoproteins
  and their functions.
• Light Heavy Alcohol, Paraoxonase Oxidized LDL
  Status.
• The major goal of this project is to evaluate the
  benefits and deleterious effects of moderate and
  heavy drinking on cardiovascular risk factors

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Bimodal Action of Alcohol on PON CAD Status
Inactive products
Up-regulated by light ethanol
LDL
HDL-PON
HDL-PON
Plaque
OX-LDL
Down-regulated by heavy ethanol
Foam Cell
Macrophage