Title: A Cowboy
1A Cowboys Worst Enemy Run Away Glucose
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3Classification
- Type 1 diabetes -results from B-cell destruction
usually leading to absolute deficiency - Type 2 diabetes -results from progressive insulin
decline on the background of insulin resistance
4Other Types
- Genetic defects in B-cell function
- Defects in insulin action
- Diseases of the exocrine pancreas (such as cystic
fibrosis) and drug or chemical induced (such as
the treatment of AIDS or after transplantation) - Gestational Diabetes
5Diabetes
- Pre-Diabetes or IGT or IFG
- Type 2 Diabetes
- Type 1 Diabetes
- Gestational Diabetes
6Diagnosing Criteria
- Pre-Diabetes or Impaired Fasting Glucose
- Blood glucose ranging between
- 100 125 mg/dl
- Or
- Glucose Intolerance during OGTT 2 hours blood
glucose reading between 140-199 mg/dl - Pre-Diabetes often is in combination with
metabolic syndrome or Syndrome X
7Diagnosing Criteria
- Type 2 Diabetes
- Random blood glucose gt 200
- Two fasting blood glucose measures 126 or greater
on two separate occasions - A blood glucose of 200 or greater at the 2 hour
mark of an oral glucose tolerance test
8Metabolic Syndrome
- High Cholesterol gt200
- High Blood Pressure gt130/80
- Low HDL lt35
- LDL gt100
- Elevated Triglycerides gt150
- Central Obesity with BMI gt25
9Screening for Diabetes
- gt45 years of age
- BMI gt 25 kg /height meters squared
- - every 3 years
10Screening for Diabetes
- Individuals may be screened at a younger age if
- Are habitually inactive
- Have a first degree relative with diabetes
- Are a member of a high risk ethnic population
- Have had a baby gt 9 lbs. or previous diagnosis of
GDM - Have had previous elevated IGT or IFG test
- Are hypertensive
- Have a diagnosis of PCO syndrome
- Have a history of cardiovascular disease
11Type 1 Diabetes
- Generally present with acute symptoms of diabetes
- -markedly elevated blood glucose
- - ketones
- - extreme thirst
- - frequent urination
- - weight loss
- - fatigue
- -blurry vision
12Gestational Diabetes
- Diabetes that occurs during pregnancy
- A risk assessment is completed at the first visit
- High risk women found to be within target at the
first screening should be re-screened at 24-28
weeks - All pregnant women are screened at 6-12 weeks
post-partum
13Diagnosing Gestational Diabetes
- One Step 100 gm OGTT
- gt95 mg/dl fasting,
- gt180 1 hour,
- gt155 2 hours,
- gt 140 3 hours
- Two Step 50 gm OGTT
- gt140 1 hour after
14Number of Millions diagnosed in the US 1980
2004
152006 Data
- It is estimated that in 2006 18.2 million people
have diabetes.
16Diagnosed with Diabetes per 100 people
17CDC Data TrendsRisk Factors for Complications
.
18Leading Causes of Death in SD
19Incidences of Diabetes in SD 7.1
20Wyoming Leading Causes of Death
21Incidence of Diabetes in Wyoming5.8
22Leading Causes of Death in North Dakota
23Incidence of Diabetes in ND 6.2
24Leading Causes of Death in Iowa
25Incidence of Diabetes in Iowa 6.7
26Diabetes Related Complications
- Related to management
- Diabetes out of control can lead to
- impaired circulation, wounds that dont heal and
amputation -
- kidney failure
- blindness
- early death from cardiovascular disease
- neuropathy
-
27Diabetic Retinopathy
- Estimated to be the most frequent cause of new
cases of blindness among adults aged 20-74
28Diabetic Retinopathy
- Optimal glycemic control can substantially reduce
the risk and progression of diabetic retinopathy - Optimal blood pressure control can reduce the
risk and progression of diabetic retinopathy - The risk is strongly related to the duration of
diabetes
29Screening for Diabetic Retinopathy
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31Laser Photocoagulation Surgery
- Beneficial in reducing the risk of further visual
loss - Not beneficial in reversing already lost acuity
- There is strong support for a screening program
to detect diabetic retinopathy
32Screening
- Early detection leads to prevention!
33Screening Leads to Delay in Diagnosis
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