Chapter 3.4: Primary Protein Structure

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Chapter 3.4 Primary Protein Structure

• CHEM 7784
• Biochemistry
• Professor Bensley

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CHAPTER 3.4 Primary Protein Structure
Todays Objectives to understand

• The levels of structure of proteins
• The importance of primary structure in proteins
• How the primary structure of a protein is
  determined

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Protein Structure (Introduction)

• Since proteins are large macromolecules, we
  describe the structure at various levels.
• Primary Structure (1º)
• Secondary Structure (2º)
• Tertiary Structure (3º)
• Quaternary Structure (4º)

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Primary Structure Importance

• Each protein has a distinctive number and
  sequence of AA residues
• Primary structure of protein determines how it
  folds up into unique 3-D structure and thus
  determines protein function

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Protein Sequencing
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Spectroscopic Detection of Aromatic Amino Acids
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Chapter 3 Summary

• In this chapter, we learned about
• The many biological functions of peptides and
  proteins
• The structures and names of amino acids found in
  proteins
• The ionization properties of amino acids and
  peptides
• The methods for separation and analysis of
  proteins