???(somatic)?????(germline)

1
?????????
2
????

• ????????????
• ???(somatic)?????(germline)
• ????
• ??????
• ??????
• ????
• ????????
• ??????

3
????

• ????????????
• ??????????????,???
• ??????????
• ?????
• ?????
• ???????????????????

4
??????

• ??????????????????
• ??????????
• ???????????
• ???????????????????
• ???????????
• ????????????
• ?????

5
?10-1
6
??????
???????????????,????? ??????,?????????????? ??????
?????????????? DNA?,????????????
7
????

• ?????
• ???
• ???????

8
?10-1
9
????????
?????????????????? ??,???????????????, ???????????
??????? ??????????????????
10
??????

• ?????????(SCID)
• ?????????(cystic fibrosis)
• ????(liver disease)

11
?10-2
12
????

• ????????
• ?????????????????
• ????????????
• ????????????????,????
• ?????
• ??????????????????
• ?????????????????????

13
?10-3
14
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• ????????????
• ???????????
• ?????????????

15
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2003?10?,???????? ????????????,???? ??SiBiono
Gene Technologies Co.,? ?????Gendicine??,????? ???
????????
16
????????

• ??????RNA????
• ???????????????
• ????(antisense therapy)
• ?????(ribozyme therapy)

17
?10-4
18
?10-5
19
?10-6?7
20
?10-8
21
????
????????????????,??????????????????????????,??????
?????,????????(virotherapy)?
22
?10-2
23
???
??????????? 1?????????????????,???
??????????????? 2?????????????????????,
????????????? 3???????????????,?????
?????????? 4??????????,???????????
24
?10-9
25
?10-10
26
???????????
??????????????,?? 1??????????????????? 2?????????
??? 3???????????????? 4????????????????? 5????????
???????,??? ??????
27
?10-11
28
??
???????????????????,????????????DNA???????????????
?????????,???????????
29
????
??????????????,????(tissue engineering)???????????
?,?????????????,?????????????????,??????????????
30
?10-3
31
?10-12
32
????
????????????????????, ????(xenotransplants),??????
??? (animal-to-human transplant)????????? ????????
?,??????????? ??,???????????????
33
????
???????????(drug delivery) ???? ??(aerosols)??,??
???? ????(transdermal patch) ?????(iontophoresis)?
????(electrotransport)
34
?????
Biosensors??????????(?????? ??????)????????????,?
?????????????????,??? ??????????????????????