Amines

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Chapter 43 Amines
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Purpose

• The object of this experiment is to identify an
  unknown amine or amine salt. First test to
  employs checking of solubility. Second experiment
  represents a Hinsberg test for distinguishing
  between primary, secondary and tertiary amines.

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Hinsberg Test

• In Hinsberg test, the sulfonamides are
  distinguishable because the derivative from a
  primary amine has an acidic hydrogen, which
  renders the product soluble in H2O. Whereas the
  sulfonamide from the secondary amine is insoluble.

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Comments

• Follow pp. 588-590 (microscale).
• Follow the lab handout for all experimental
  procedures. Wearing rubber gloves is necessary
  during this lab. You will work with toxic and
  corrosive compounds.
• Use solubility and Hinsberg test to figure out
  the unknown structures.

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Safety

• Amines are toxic and have a characteristic smell
  work in the hood. Do not swallow, do not inhale
  and avoid contact with eyes and skin. Wear gloves
  and handle with caution.
• Benzenesulfonyl chloride is corrosive, avoid
  contact with skin and eyes, wear gloves and
  goggles, use caution.