Title: Folie 1
1Heterocyclic Chemistry
CHEMISTRY OF HETEROCYCLIC COMPOUNDS
Heterocyclic
Chemistry
2WHAT IS HETEROCYCLIC CHEMISTRY?
What are carbocyclic compounds?
3Carbocyclic Compound
Carboxylic Compound Carboxylic Compound
Aromatic Compound Cyclic Compound
4Whats aheterocyclic compound?
If the ring system is made up of carbon atoms and
at least one other element, the compound can be
classified as hetero cyclic. The elements that
are found most commonly together with carbon in a
ring system are Nitrogen (N), Oxygen(O), and
Sulfur(S).
5Heterocyclic Chemistry
Heterocyclic compounds are organic compounds
that contain a ring structure containing atoms in
addition to carbon, such as sulfur, oxygen or
nitrogen, as the heteroatom.
6Heterocyclic Chemistry
Heterocyclic classification
It can be classified into
7Heterocyclic Chemistry
Heterocyclic classification
1- Aliphatic heterocycles -
8Heterocyclic Chemistry
2- Aromatic heterocycles - a- six-membered
aromatic hetrocycles
Pyrimidine
9Heterocyclic Chemistry
2- Aromatic heterocycles -
b- five-membered aromatic hetrocycles
10Heterocyclic Chemistry
2- Aromatic heterocycles -
c- bicyclic heteroaromatic compounds
11Heterocyclic Chemistry
- Importantce and uses of Heterocyclic compounds-
- Biosynthesized
- Essential for life ( haem, chlorophyll)
- Their metabolitis used as
- - toxin towords off predators
- - colouring agents to attact mates
- In general various important compounds such as-
- alkaloids, vitamins, antibiotics, essential amino
acids, hormones, drugs and dyes contain
heterocyclic structure. -
12Heterocyclic Chemistry
in general nucleic acids, amino acids
(proteins), feeding proteins, carbohydrates,
vitamins alkaloids nicotine,
caffeine Application antibiotics
(penicillins, sulfonamides) insecticides
(triazoles) herbicides (triazines, pyridines)
13Heterocyclic Chemistry
2/3 of all organic compounds are
heterocyclic compounds
14Heterocyclic Chemistry
- The main focus-
- Five-membered systems containing one heteroatom
- Six-membered system containing one heteroatom
15HETEROCYCLIC NOMENCLAUTURE