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General Medical Emergencies: Part I

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General Medical Emergencies: Part I. Major TopicsCommunicable / Infectious Diseases. HIV Infection and AIDS. Diphtheria. Encephalitis. Hepatitis. Herpes: Disseminated. – PowerPoint PPT presentation

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Title: General Medical Emergencies: Part I


1
General Medical Emergencies Part I
2
Major TopicsCommunicable / Infectious Diseases
  • Mononucleosis
  • Mumps
  • Pertussis
  • Shingles (Herpes Zoster)
  • Tuberculosis
  • Varicella (Chickenpox)
  • HIV Infection and AIDS
  • Diphtheria
  • Encephalitis
  • Hepatitis
  • Herpes Disseminated
  • Measles
  • Meningitis

3
Major TopicsSkin Infestations
  • Lice
  • Scabies
  • Myiasis

4
Major TopicsEndocrine Emergencies
  • Adrenal Crisis
  • Diabetic Ketoacidosis
  • Hyperglycemic Hyperosmolar Nonketotic Coma
  • Hyperglycemia
  • Myxedema Coma
  • Thyroid Storm

5
HIV Infection and AIDS
  • Caused by a retrovirus
  • Viral symptoms start 2-6 weeks
  • Antibody seroconversion takes
  • place within 45 days - 6 months
  • Asymptomatic period for months
  • to years
  • Replication, mutation, and destroying the immune
    system

6
HIV Infection and AIDS
  • Persistent generalized lymphadenopathy occurs
  • Constitutional disorders, neurological disorders,
    secondary infections, secondary cancers, and
    pneumonitis

7
HIV Infection and AIDS
  • All HIV infections will develop into AIDS
  • Mean between exposure to HIV to AIDS-10 years
  • AIDS to death
  • Sooner the treatment, better long-term survival

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HIV Infection and AIDS Assessment
  • Subjective data
  • History of present illness
  • Generalized lymphadenopathy, persistent
  • Fever for longer than 1 month
  • Episodic spiking
  • Persistent low-grade fever
  • Diarrhea for longer than 1 month
  • Weight loss
  • Anorexia
  • Night Sweats

10
HIV Infection and AIDS Assessment
  • Malaise or fatigue, arthralgias, myalgias
  • Mild opportunistic infections
  • Oral candidiasis
  • Herpes Zoster
  • Tinea
  • Skin lesions, rashes
  • Cough
  • Broad range of neurological complaints, both
    focal and global, including dementia

11
HIV Infection and AIDS Assessment
  • Current medications
  • Antiretroviral agents zidovudine (AZT),
    zalcitabine (ddC), didanosine (ddI), stavudine
    (d4T), lamivudine (3TC), nevirapine, delavirdine
  • Pneumocystis prophylaxis trimethoprim-sulfameth
    oxazole, pentamidine, dapsone
  • Protease inhibitors indinavir, saquinavir
    mesylate, nelfinavir, ritonavir

12
HIV Infection and AIDS Assessment
  • Medical History
  • Blood transfusions, especially before 1985
  • Hemophilia
  • Occupational needle sticks or blood exposure
  • Sexually transmitted diseases (STDs)
  • Tissue transplantation
  • Infant with HIV-positive mother
  • Sexual contact with IV drug user
  • Sexual contact with HIV-positive partner
  • Sexual practices including multiple partners,
    anal sex, oral-anal sex, or fisting
  • Recent TB exposure

13
HIV infection and AIDS
  • Physical examination
  • Chronically ill appearance
  • Kaposis sarcoma skin lesions
  • Chest crackles and wheezes
  • Dyspnea
  • Abnormal vital signs
  • Lymphadenopathy
  • Dementia
  • Wasting syndrome signs of volume depletion
  • Withdrawn, irritable, apathetic, depressed
  • Slow, unsteady gait weakness poor coordination

14
HIV Infection and AIDS
  • Diagnostic procedures
  • CXR
  • CBC
  • Anemia
  • Lymphopenia
  • Thrombocytopenia
  • ABGs
  • Electrolytes, liver function tests

15
HIV Infection and AIDS Assessment
  • Determination of HIV antibodies (e.g., via
    enzyme-linked immunosorbent assay ELISA and
    Western blot analysis)
  • decreased CD4 cell count
  • blood cultures
  • urinalysis
  • TB skin test (5 mm is positive in HIV infected
    person)

16
Diphtheria
  • Alteration in neurological functions
  • Lethargy
  • Withdrawal
  • Confusion
  • Cranial nerve neuropathies
  • Alteration in cardiac functions
  • ST-and T-wave changes
  • First-degree heart block
  • Dyspnea, heart failure, circulatory collapse
  • Anxiety

17
Diphtheria
  • Diagnostic procedures
  • Throat culture specimen swabbed from beneath
    membrane or piece of membrane
  • Notify lab that C. diphtheria is suspected
    requires special media and handling

18
Diphtheria
  • Interventions
  • Provide strict respiratory isolation
  • Maintain airway, breathing, circulation
  • Monitor vital signs and pulse ox
  • Assemble emergency cricothyrotomy equipment at
    bedside
  • Administer O2 for dyspnea or cyanosis
  • Establish IV catheter for administration of IV
    fluids

19
Diphtheria
  • Interventions
  • Diphtheria antitoxin
  • Equine serum
  • Test for sensitivity
    (intradermal or mucous membrane)
    before administration
  • Often administered before diagnosis is confirmed
    because of virulence of disease

20
Diphtheria
  • Antibiotic EES or PCN G
  • Antitussive
  • Antipyretic
  • Topical anesthetic agent
  • Minimize environmental stimuli
  • Instruct patient on importance of complete bed
    rest

21
Diphtheria
  • Provide immunization
  • Regular booster Q10years, combined with TD, after
    completion of initial series of 3 doses
  • Identify close contacts
  • Culture and prophylactic Booster of TD in none
    within 5 years
  • Antibiotics
  • Active immunization for nonimmunized persons
    (series of 3 doses)

22
Encephalitis
  • Viral infection of the brain
  • Often coexists with meningitis and has
  • broad range of SS
  • Most cases in North America, caused by
    arboviruses, herpes simplex I, varicella-zoster,
    EB, and rabies
  • Transmission by animal bites, or seasonally form
    vectors (mosquitoes, ticks, and midges)
  • More common human viruses are airborne via
    droplet or lesion exudate
  • All age groups, with mortality from 5-10 from
    arboviruses and 100 for rabies

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Encephalitis
  • Assessment
  • Subjective
  • History of present illness
  • Recent viral illness or herpes zoster
  • Recent animal or tick bite
  • Travel to endemic area, season of the year
  • Fever
  • Headache
  • Photophobia
  • Nausea, vomiting
  • Confusion, lethargy, coma
  • New psychiatric symptoms

25
Encephalitis
  • Assessment
  • Subjective
  • Medical history
  • Immune disorders
  • Allergies
  • Medications

26
Encephalitis
  • Objective data
  • Physical exam
  • Altered LOC
  • Rash specific to cause
  • Meningism
  • Altered reflexes
  • Focal neurological findings
  • Abnormal movements
  • Seizures

27
Encephalitis
  • Diagnostic Procedures
  • Lumbar puncture, CT scan
  • CBC
  • Blood cultures
  • Serology

28
Encephalitis
  • Interventions
  • Institute standard precautions and isolation
    until causative agent identified
  • Monitor airway, breathing, circulation
  • Monitor vital signs and pulse oximeter
  • Administer O2
  • Prepare to assist with intubation
  • Insert large bore IV catheter, and administer
    isotonic solutions as ordered
  • Administer medications as ordered

29
Encephalitis
  • Administer antimicrobial/antiviral agents,
    steroids
  • Monitor blood sugar and electrolytes
  • Insert urinary catheter PRN
  • Monitor IO, cerebral edema, keep HOB gt30 degrees
  • Institute seizure precautions
  • Elevate HOB 30 degrees

30
Encephalitis
  • Restrict IV fluids
  • Keep body temperature normal
  • Administer diuretics as ordered
  • Explain procedures and disease to family/patient
  • Allow patient/significant others to verbalize
    fears
  • Prepare patient/family for admission to hospital

31
Hepatitis
  • Viral syndrome involving hepatic triad (bile
    duct, hepatic venule, and arteriole, and central
    vein area.
  • Hep A-fecal-oral route, infectious for 2 weeks
    before and 1 week after jaundice
  • Hep B-(HBV)blood and sexual contact and consists
    of 3 antigens
  • Hep B surface

32
Hepatitis
  • Hep B-(HBV) blood and sexual contact
  • 3 antigens
  • Hep B antigens
  • Persistence of core antibody indicates chronic
    infection
  • Persistence of surface antibody indicates
    immunity to reinfection
  • Hep B surface antigen in the serum without
    symptoms is indicative of a carrier state

33
Hepatitis
  • Hep C identified by antihepatitis C virus
    antibody
  • 50 of Hep C become chronic, and no immunity is
    developed
  • Hep C 90 of hepatitis cases transmitted by
    blood transfusion

34
Hepatitis
  • Hep E is an epidemic, enterically transmitted
    infection from shellfish and contaminated water
  • Hep D found with acute or chronic HBV infection
  • Chronic infections result in cirrhosis and liver
    cancer

35
Hepatitis
  • Assessment
  • History of present illness
  • Prodrome preicteric phase, occurs 1 week before
    jaundice
  • Low-grade fever
  • Malaise earliest,
    most common symptom
  • Arthralgias
  • Headache
  • Pharyngitis
  • Nausea, vomiting

36
Hepatitis
  • History of Illness contd
  • Rash, with type B usually
  • May or may not progress to icteric phase
  • Incubation
  • A 15-45 days
  • B 30-180 days
  • C 15-150 days
  • Duration
  • A 4 weeks
  • B AND C 8 weeks

37
Hepatitis
  • Icteric phase
  • Disappearance of other symptoms
  • Anorexia
  • Abdominal pain
  • Dark urine
  • Pruritus
  • Jaundice

38
Hepatitis contd
  • Medical History
  • Immunizations
  • ETOH consumption
  • Allergies
  • Medications all are significant
  • Blood transfusions, IV drug use, Hemophilia or
    dialysis
  • Chronic medical problems, travel, living in
    institution
  • Living in recent floods or natural disasters

39
Hepatitis
  • Objective data
  • Physical exam
  • Posterior cervical lymph node enlargement
  • Enlarged, tender liver
  • Splenomegaly in 20
  • Jaundice
  • Vital signs may have tachycardia, hypotension
  • Fever

40
Hepatitis
  • Diagnostics
  • Liver enzymes SGOT SGPT elevated
  • Direct and indirect bilirubin levels elevated
  • Alkaline phosphatase elevated
  • Differential leukocyte count leukopenia with
    lymphocytosis, atypical lymphocytes
  • CBC, UA elevated bilirubin, PT elevated, ABD
    X-ray
  • Antigen and/or antibody titers

41
Hepatitis
  • Interventions
  • Provide increased calories
  • Monitor for signs of dehydration, replacement
    with isotonic solution
  • Record IO
  • Assess support systems of patients
  • Hospitalize if unable to care for self or PT gt15
    seconds

42
Hepatitis
  • Initiate prophylaxis
  • Type A
  • Immune serum globulin 80-90 effective if 7-14
    days after exposure
  • Vaccine administered in two doses given to
    high-risk population foreign travel, endemic
    areas (e.g. Alaska), military, immunocompromised
    or risk for HIV, chronic liver disease, hep C
  • Type B hepatitis B immune globulin plus
    vaccination, for exposure to serum, saliva,
    semen, vaginal secretions, breast milk

43
Hepatitis
  • Initiate prophylaxis
  • Type B vaccination with HBV vaccine inactivated
    (Recombivax HB)
  • Vaccinate high-risk persons
  • Health care and public safety workers, clients
    and staff at institutions
  • Hemodialysis patients, recipients of clotting
    factors
  • Household contacts and sexual partners of HBV
    carriers
  • Adoptees from countries where HBV in endemic
    Pacific Islands and Asia
  • IV Drug users, sexually active homosexual and
    bisexual men
  • Sexually active men and women with multiple
    partners
  • Inmates of long-term correctional facilities

44
Hepatitis
  • Vaccinate all infants (universally) regardless of
    hepatitis B surface antigen status of mother
    (administer first dose in newborn period,
    preferably before leaving hospital)
  • Report to appropriate health departments
  • Limit exposure of medical personnel to blood,
    secretions, and feces

45
Hepatitis
  • Instruct patient/significant others
  • Strict hygiene, private bathroom if possible
  • Diet of small, frequent feedings low in fat, high
    in carbs, patient should avoid handling food to
    be consumed by others
  • SS bleeding, vomiting, increased pain
  • Take meds as prescribed
  • Avoid intake of alcohol
  • Take meds only if necessary
  • Avoid steroids they delay long-term healing

46
Herpes Disseminated
  • Herpes simplex virus (HSV)
  • is a relatively benign disease when cutaneous
  • Can invade all body systems and lead to death
  • Primary viremia occurs from spill-over of the
    virus at the site of entry
  • During the second stage, HSV disappears from he
    blood but grows within cells of infected organs,
    which in turn causes seeding to other organ
    systems.
  • Dissemination occurs in susceptible persons
    newborns, malnourished children, children with
    measles, people with skin disorders, such as
    burns, eczema, immunosuppression, and
    immunodeficiency, especially HIV

47
Herpes Disseminated
  • HSV has a predilection for temporal lobe.
  • Encephalitis most common
  • 70 mortality rate without treatment
  • 50 with treatment residual neurological
    deficits
  • Latency period within sensory nerve resulting in
    mild or life-threatening infection years later

48
Herpes
  • Assessment
  • Subjective data
  • History of present illness
  • Onset usually acute
  • After other illness
  • After outbreak of cutaneous infection
  • After any stressor

49
Herpes
  • Assessment
  • Subjective data
  • History of present illness
  • Symptoms depend on organ system affected
  • Neurological system headache, confusion,
    seizures, coma, olfactory hallucinations
  • Liver ABD pain, vomiting
  • Lung cough, fever
  • Esophagus dysphagia, substantial pain, weight
    loss

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51
Herpes
  • Medical history
  • HSV infection
  • Chronic illness, cancer, HIV
  • Medications immunosuppressants
  • Allergies

52
Herpes
  • Objective data
  • Physical exam
  • Fever
  • Other vital sign abnormalities depend on organ
    system involved
  • Focal neurological signs
  • Anosmia (loss of smell)
  • Aphasia
  • Temporal lobe seizures
  • Confusion, somnolence, coma
  • Respiratory
  • crackles

53
Herpes
  • Diagnostic Procedures
  • Viral cultures blood and skin
  • Lumbar puncture cerebrospinal fluid for culture
  • Biopsy of target organ, especially brain
  • Clotting studies for DIC
  • Liver Function
  • CBC

54
Herpes
  • Interventions
  • Prepare to assist intubation
  • O2 PRN
  • Monitor
  • VS with PO
  • Neurological status
  • Maintain airway, breathing, circulation
  • IO
  • Administer Antiviral meds
  • FC PRN
  • Establish IV of isotonic solution at rate to
    maintain blood pressure and fluid balance
  • Protect from injury from seizures
  • Explain procedures and illness to patient or
    significant others
  • Practice standard precautions

55
Measles
  • Highly acute and contagious virus
  • Caused by rubeola virus, late winter and early
    spring
  • Airborne droplets, incubation 10-14 days
  • Contagious few days before and after onset of
    rash
  • Most recover, incidence of OM, diarrhea,
    pneumonia, and encephalitis

56
Measles
  • More serious in infants and in malnourished
    children, pregnancy with preterm delivery and
    spontaneous abortion
  • Most born lt1957 are permanently immune
  • Vaccine (MMR) 12-15 months, active disease or two
    immunizations in childhood
  • Booster elementary school, all
    high school or college
    revaccinated unless active
    disease or two
    immunizations

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59
Measles
  • Assessment
  • Subjective data
  • History of present illness
  • Exposure to measles
  • Prodrome
  • Fever
  • Cough
  • Coryza (nasal mucosal inflammation)
  • Photophobia
  • Anorexia
  • Headache
  • Rarely seizures

60
Measles
Subjective
  • Medical history
  • Immunizations
  • History of measles
  • Current age born before 1957
  • Allergies
  • Medications

61
Measles
  • Objective data
  • Physical exam
  • Fever
  • Kopliks spots on buccal mucosa (bluish-gray
    specks on red base)
  • Conjunctivitis
  • Harsh cough

62
Measles
  • Red, blotchy rash
  • Appears on third to seventh day
  • Maculopapular, then becomes confluent as
    progresses
  • Starts on face, then generalized to the
    extremities
  • Mild desquamation
  • Lasts 4-7 days
  • Vital signs normal, except fever
  • Neurological system may have altered LOC,
    encephalitis
  • Respiratory system may have OM, pneumonia

63
Measles
  • Diagnostic procedures
  • Viral cultures (expensive and difficult, so not
    usually done)
  • Immunoglobulin M antibodies measles specific
  • CBC leukopenia
  • Other studies if seriously ill

64
Measles
  • Interventions
  • Provide respiratory isolation
  • Isolate patient/significant others from other
    people in waiting room
  • Advise patient to avoid school, day care centers,
    and people outside immediate family until after
    contagious period
  • Initiate immunization of high-risk contacts
  • Live vaccine if given within 72 hours of exposure
    (use monovalent vaccine if infants younger than
    12 months need reimmunization at 15 months with
    MMR)
  • Immune globulin up to 6 days after exposure
  • Immunocompromised persons should receive immune
    globulin even if previously immunized

65
Measles
  • Encourage rest in darkened room
  • Administer acetaminophen for fever
  • Encourage parents to have children immunized at
    appropriate times
  • Instruct patient/parent about SS of serious
    illness or complications
  • Persistent fever or cough
  • Change in mental status
    or seizures
  • Difficulty in hearing

66
Meningitis
  • Bacterial or viral of the pia and arachnoid
    meniges
  • Late winter or early spring
  • Viral mild and short lived
  • Bacterial severe and life threatening
  • Streptococcus pneumoniae, Haemophilus influenzae
    (H. flu), and Neisseria meningitidis subgroups A,
    B, and C
  • H. Flu incidence decreased because of vaccination
  • Bacteria can enter the blood, basilar skull
    fracture, infected facial structures, and brain
    abscesses

67
Meningitis
  • Bacteria initially colonize in the nasopharynx
  • In bacterial disease, the subarachnoid space is
    filled with pus, which obstruct CSF, resulting in
    hydocephalus and increased ICP
  • Infants and elderly often do not exhibit classic
    signs of meningeal irritation and fever
  • Death most common within a few hours after
    diagnosis
  • Up to 33 of pediatric survivors left with some
    type of permanent neurological dysfunction
  • Any infant younger that 2 months with a fever,
    must be evaluated for meningitis

68
Meningitis
  • Assessment
  • Subjective data
  • History of present illness
  • Antecedent illness or exposure
  • Onset sudden
  • Headache, especially occipital
  • Fever and chills
  • Anorexia or poor feeding
  • Vomiting and diarrhea
  • Malaise, weakness
  • Neck and back pain
  • Restlessness, lethargy, altered mental status
  • Disinclination to be held infants
  • Seizures
  • Recent basilar skull fracture

69
Meningitis
  • Medical history
  • Medications
  • Allergies
  • Immunizations if child
  • Chronic disease liver or renal, DM, multiple
    myeloma, alcoholism, malnutrition
  • Asplenic
  • Recurrent sinusitis, pneumonia, OM, mastoiditis

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Meningitis
  • Objective data
  • Physical examination
  • High-pitched cry in infants
  • Hyperthermia gt101 or hypothermia lt96
  • Petechiae that do not blanch 1-2 mm on trunk
    and lower portion of body, also mouth, palpebral
    and ocular conjunctiva
  • Purpura
  • Cyanosis, mottled skin, and pallor

72
Meningitis
  • Objective data
  • Physical examination
  • Vital signs
  • Tachycardia, hypotension, tachypnea
  • Bradycardia in neonates
  • Meningeal irritation persons older than 12
    months, seen in about 50
  • Contraction and pain of hamstring muscles occur
    after flexion and extension of leg Kernigs
    sign
  • Bending of neck produces flexion of knee and hip
    passive flexion of lower limb on one side
    produces similar movement on other side
    Brudzinskis sign
  • Nuccal rigidity

73
Meningitis
  • Infants with meningeal irritation cry when held
    and are more quiet when left in crib
  • Photophobia
  • Focal neurological signs, cranial nerve palsies,
    and generalized hyperreflexia
  • Altered mental status
  • Confusion, delirium, decreased LOC
  • Lethargy and confusion may be only
    signs in elderly
  • Bulging fontanelle
  • Irritability

74
Meningitis
  • Diagnostic procedures
  • Blood glucose levels infants younger than 6
    months are prone to hypoglycemia
  • Electrolyte levels hyponatremia
  • BUN and creatinine levels
  • Serum osmolality
  • Low because of inappropriate vasopressin
    secretion
  • High because of dehydration

75
Meningitis
  • Diagnostic procedures
  • CBC
  • Bacterial high WBC
  • Viral normal or low WBC
  • Meningococcal WBC tends to
    be less that 10,000
  • Blood cultures
  • ABGs if severely ill
  • Clotting studies
  • UA
  • CXR and skull radiographs

76
Meningitis
  • Lumbar puncture CSF
  • Bacterial infection cloudy appearance elevated
    pressure WBC 200-20,000 with increased
    polymorphonuclear cells glucose level decreased
    protein level elevated bacteria present on
    Grams stain
  • Viral infection clear appearance WBC lt500
    normal pressure glucose level normal no
    bacteria present on Grams stain

77
Meningitis
  • Interventions
  • Ensure that health care providers wear masks if
    infection with meningococcus is suspected
  • Undress patient completely to check for petechiae
  • O2 PRN
  • Monitor VS
  • Prepare to suction and assist with aggressive
    ventilatory support as needed
  • Prepare to assist with LP
  • Insert NG to prevent aspiration

78
Meningitis
  • Establish IV catheter, IO in necessary
  • Monitor IV fluids as related to IO or excessive
    secretion of antidiuretic hormone
  • KCL replacement PRN, antiemtics PRN
  • Infuse antibiotics (usually ampicillin,
    aminoglycosides, cephalosporins)
  • Administer benzodiazepines, corticosteroids
  • Control fever
  • Reduce ICP
  • Use hyperventilation with caution to avoid
    cerebral ischemia
  • Elevate HOB 30 degrees
  • Administer barbiturates and diuretics

79
Meningitis
  • Insert FC, monitor IO
  • Monitor for signs of dehydration or fluid excess
  • Monitor mental status and neurological signs
    every 15 minutes to 1 hour, depending on
    patients stability
  • May need to restrain confuse patient
  • Protect seizing patient form physical harm
  • Explain procedures and need for ICU

80
Meningitis
  • Administer chemprophylaxis(rifampin, ceftriaxone)
    within 24 hours of disease identification to
    household contacts, day care center contacts, and
    health care providers if bacterial disease
  • Side effects GI, lethargy, ataxia, chills, fever,
    and red-orange urine, feces, sputum, tears, and
    sweat
  • Soft contact lenses may be permanently stained
    with rifampin use
  • Medication may need to be taken with food for GI
    intolerance, although it is best absorbed on
    empty stomach
  • Birth control pills may not work
  • Do not give to pregnant women

81
Meningitis
  • Educate parents to have infants immunized against
    H. Flu B beginning at 2 months

82
Mononucleosis
  • Acute viral illness with broad range of SS
    lasting 2-3 weeks, very contagious
  • EBV transmitted in saliva
  • About 50 of the population serovonverts to EBV
    before 5 years of age with sublclinical infection
    or mild illness
  • Another wave of seroconversion in med adolescence
  • Peak 15-24-years
  • Incubation 2-5 weeks
  • CMV is the other most frequent causative agent
  • Complications include glomerulonephritis,
    autoimmune hemolytic anemia, pericarditis,
    hepatitis, guillain-Barre syndrome, meningitis,
    and pneumonia

83
Mononucleosis
  • Rarely death may occur from splenic rupture or
    airway obstruction as a result of tonsillar
    hypertrophy
  • Assessment
  • Subjective data
  • History of present illness
  • Prodrome lasting 3-5 days malaise, anorexia,
    nausea and vomiting, chills/diaphoresis, distaste
    for cigarettes, headache, myalgias

84
Mononucleosis
  • History of present illness
  • Subsequent development of fever 100.4 to 104
    lasting 10-14 days, sore throat,diarrhea, earache
  • Medical history
  • Exposure to mononucleosis,
    usually not known
  • Allergies
  • Medications

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Mononucleosis
  • Objective data
  • Physical examination
  • May appear acutely ill
  • Red throat with exudate tonsils may be
    hypertrophied
  • Tender lymphadenopathy, particularly posterior
    cervical
  • Petechiae on palate
  • Fine red macular rash 5 of adults if given
    ampicillin, 90-100 of patients will experience
    rash
  • Abdominal tenderness with heptomegaly
  • Splenomegaly in 50 of patients

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Mononucleosis
  • Diagnostic procedures
  • Heterophile antibody titer (Monospot) positive
    by second week of illness may remain negative in
    children younger than 5 years
  • Throat culture to rule out group A streptococcus
  • CBC neutropenia, thrombocytopenia,
    lymphocytosis with atypical lymphs, leukocytosis
  • Liver functions may be abnormal
  • CXR if pneumonia suspected

89
Mononucleosis
  • Interventions
  • Isolation not necessary
  • Avoid kissing
  • No sharing eating or drinking utensils
  • Activity as tolerated
  • Extra rest early in illness
  • Avoid heavy lifting and contact sports for at
    least 4 weeks if splenomegaly present

90
Mononucleosis
  • Interventions
  • Administer antipyretics, analgesics (Avoid ASA)
  • Administer corticosteroids therapy for severe
    Pharyngitis, evolving airway obstruction, chronic
    or disabling symptoms, or profound splenomegaly

91
Mononucleosis
  • Warm salt water gargles for sore throat
  • Encourage fluids to avoid dehydration
  • Diet as tolerated
  • Liquids initially
  • Soft foods
  • Do not donate blood for 6 months

92
Mononucleosis
  • Instruct patient about SS of serious illness or
    complications
  • Increased fever
  • Cough, chest pain
  • Progression of innless
  • Difficulty breathing
  • Signs of dehydration
  • Increasing abdominal pain

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Mumps
  • Acute, usually benign, viral infection caused by
    Paramyxoviridae family
  • Swelling and tenderness of salivary glands and
    one or both parotid glands
  • Direct contact, droplet nuclei, or fomites
  • Incubation averages 16-18 days
  • Peak incidence is January to May
  • Most contagious just before swelling
  • More severe illness in the post pubertal age
    group 20-30 of adult men experience
    epididymoorchitis
  • Complications include viral meningitis,
    arthritis, arthralgias, and pancreatitis

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Mumps
  • Assessment
  • Subjective data
  • History of present illness
  • Exposure to mumps
  • Prodrome fever (lt104), anorexia, malaise,
    headache
  • Earache and tenderness of ipsilateral parotid
    gland
  • Citrus fruits or juices increase pain
  • Fever, chills, headache, vomiting if meningitis
  • Testicular pain if orchitis
  • Abdominal pain if pancreatitis

96
Mumps
Subjective contd
  • Medical history
  • Childhood immunizations
  • Previous mumps
  • Allergies
  • Medications

97
Mumps
  • Objective data
  • Physical examination
  • Swelling of gland, maximal over 2-3 days, with
    earlobe lifted up and out and mandible obscured
    by swelling
  • Trismus with difficulty in pronunciation and
    chewing
  • Testicle warm, swollen, tender
  • Scrotal redness

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Mumps
  • Diagnostic procedures
  • CBC WBC and differential normal or mild
    leukopenia
  • Serum amylase elevated
  • for 2-3 weeks

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Mumps
  • Interventions
  • Provide respiratory isolation
  • Advise to avoid school/work until swelling gone
  • Administer analgesics
  • Encourage rest until feeling better
  • Encourage fluids, avoid citrus
  • Warm or cold packs
  • For orchitis
  • Bed rest
  • Scrotal elevation
  • Ice packs
  • Pain meds

101
Mumps
  • Administer IV fluids for acutely ill patients
  • Recommend immunization to family and health
    workers who have no mumps antibodies

102
Pertussis
  • Acute, widespread, highly contagious bacterial
    disease of the throat and bronchi
  • Gram-negative Coccobacillus Bordetella Pertussis
  • Airborne droplets
  • Most common children lt4 years
  • Females higher incidence of morbidity and
    mortality
  • Partially immunized children have less severe
    illness
  • Adults have only minor respiratory symptoms and
    persistent cough, majority unrecognized

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Pertussis
  • Vaccine immunity is lt12 years, most adults are
    not protected
  • Incubation period 7-10 days but can vary 6-21
  • Peak incidence is during late summer and early
    fall
  • Pertussis bacteria invade the mucosa of URT
  • Complications include pneumonia, pneumothorax,
    seizures, and encephalitis
  • Children also frequently experience laceration of
    the lingual fremulum and epistaxis

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Pertussis
  • Assessment
  • Subjective data
  • History of present illness
  • Exposure to pertussis
  • Three stages last up to 2 weeks
  • Conjuctivitis and tearing
  • Fever/chills
  • Rhinorrhea, sneezing
  • Irritability
  • Fatigue
  • Dry nonproductive cough, often worse at night

106
Pertussis
  • Paroxysmal lasts 2-4 weeks
  • Severe cough with hypoxia, unremitting paroxysms,
    and clear, tenacious mucous patient appears well
    between paroxysims of coughing cough often
    triggered by eating and drinking
  • Apnea can occur in rate cases
  • Vomiting follows cough
  • Anorexia
  • Convalescent residual cough

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Pertussis
  • Medical history
  • Recent illness or infection
  • Medications
  • Allergies
  • Immunization status

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Pertussis
  • Objective data
  • Physical exam
  • Paroxysmal explosive coughing ending in prolonged
    high-pitched crowing inspiration
  • Coryza
  • Clear, tenacious mucous in large amounts
  • Temperature gt101
  • Restlessness
  • Crepitus from subcutaneous emphysema
  • Periobital/eyelid edema

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Pertussis
  • Diagnostic procedures
  • CS testing of nasopharynx using calcium alginate
    dacron-tip swab
  • Immunofluorescent antibody staining of
    nasopharyngeal specimens
  • CBC with differential leukocyte count
    lymphocytosis

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Pertussis
  • Interventions
  • Maintain respiratory isolation
  • Monitor vital signs and respiratory status
  • Be prepared to assist with intubation
  • O2 PRN
  • Isolate patients with active disease from school
    or work until they have taken antibiotics for 14
    days
  • Monitor for signs of dehydration or nutritional
    deficiency secondary to vomiting

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Pertussis
  • Administer prescribed medication
  • Antibiotic EES
  • Antitussive
  • Analgesic
  • Antipyretic
  • Position comfortably

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Pertussis
  • Admit patients younger than 1 year prepare for
    nasotracheal suctioning
  • Initiate immunization
  • Educate parents about importance of complete
    immunization
  • Household and other contacts lt1year
    prophylactic EED
  • Household and close contacts ages 1-7 years who
    had less than four DTP vaccine doses or more that
    3 years since
  • EES for 14 days
  • DTP immunization

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Pertussis
  • Review SS that necessitate return to ER
  • Difficulty in breathing recurs or worsens
  • Blue color of lips or skin
  • Restlessness or sleeplessness develops
  • Medicines are not tolerated
  • Fluid intake decreases

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Shingles (herpes zoster)
  • Acute localized infection cause by
    varicella-zoster virus (VZV)
  • During chickenpox, VZV travels from skin lesions
    to sensory nerve ganglia sets up latent infection
  • Postulated that when immunity to VZV wanes, the
    virus replicates
  • VZV moves down nerves, causing dermatomal pain
    and skin lesions
  • Lasts up to 3 weeks
  • Exact triggers unknown, old age and
    immunosuppression are risk factors

115
Shingles
  • 20 of population
  • 4 second exposure
  • Fluid from lesion is contagious, but likelihood
    of transmission is low
  • Susceptible exposed persons may develop varicella
    (chickenpox)
  • Complications post herpetic neuralgia,
    debilitation pain syndrome lasts several months,
    blindness, disseminated disease, and occasionally
    death

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Shingles
  • Assessment
  • Subjective data
  • History of present illness
  • Pain, itching, tingling, burning of involved
    dermatome precede rash by 3 to 5 days
  • Rarely headache, malaise, fever
  • Medical history
  • History of chickenpox, HIV infection, cancer,
    chronic steroid use
  • Allergies
  • Medications

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Shingles
  • Objective data
  • Physical examination
  • Tenderness over involved dermatome
  • Rash
  • Unilateral does not cross midline
  • Usually thoracic or lumbar dermatome
  • Small fluid-filled vesicle on red base
  • May become hemorrhagic
  • New lesions occur for about 1 week

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Shingles
  • Fever (low grade if present)
  • Visual acuity, if eye involved
  • Diagnostic procedures
  • Viral culture
  • Other studies if seriously ill

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Shingles
  • Interventions
  • Provide contact isolation
  • Advise patient to avoid school/work until all
    lesions are crusted over
  • Recommend immunizations of high-risk contacts
  • Varicella-zoster immune globulin (VZIG)

121
Shingles
  • Administer medications as prescribed
  • Analgesics
  • Antihistamines
  • Antivirals (acyclovir, famciclovir) will lessen
    disease severity and incidence of post herpetic
    neuralgia if administered within 72 hours of
    onset of rash

122
Shingles
  • To prevent infection of lesions, cut fingernails
    short
  • Topical baking soda paste or baths and calamine
    lotion may help
  • Ophthalmological consult if facial/eye
    involvement
  • Instruct patient about SS of serious illness or
    complications
  • Increased fever
  • Cough
  • Becoming more ill
  • Signs of skin infection

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Skin infestations Lice
  • Three types of lice infest humans
  • Pediculus humanus var corporis (human louse)
  • 2-4mm, grayish-white, flattened, wingless, and
    elongated with pointed heads
  • Overcrowding and poor sanitation

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Skin infestations Lice
  • Three types of lice infest humans
  • P. humanus var capitis (human head louse)
  • Wider and shorter, resemble a crab
  • Eggs (nits) laid by female
  • Affects all socioeconomic groups
  • Phthirus pubis (pubic or crab louse)
  • Sexually or close body contact
  • Can be seen eyebrows, eyelashes, axillary hair,
    and back and chests
  • 33 with lice have 2nd STD

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Lice
  • Can cause significant cutaneous disease
  • Lice serve as vectors for typhus, relapsing
    fever, and trench fever

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Lice
  • Assessment
  • Subjective data
  • History of present illness
  • Itching infected areas
  • Fever, malaise in severe infection
  • Exposure to lice
  • Recent sharing of clothing, beds, combs/brushes
  • Concurrent STDs

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Lice
  • Medical history
  • Previous infestations
  • Allergies
  • Medications
  • Objective data

129
Lice
  • Physical exam
  • Excoriation of scalp
  • Secondary bacterial infection, especially of
    scalp
  • Weeping and crusting of skin
  • Lymphadenopathy
  • Small, red macules, papules on trunk
  • Small,gray to bluish macules measuring lt1cm on
    trunk(maculae ceruleae) from anticoagulant
    injected into skin by biting louse
  • Nits on hairs
  • Thick, dry skin, brownish pigmentation on neck,
    shoulder, back form chronic infection
  • Signs of concurrent STDs

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Lice
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Lice
  • Interventions
  • Contact isolation
  • Advise patient/parent to avoid school/work until
    one treatment completed
  • Administer analgesics, antihistamines, antibiotics

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Lice
  • Interventions
  • Use pediculicides
  • Pyrethrin liquid
  • Permethrin crème
  • Treat sexual contacts
  • Administer medications for STDs
  • Instruct patient/parent that itching may continue
    after treatment do not re-treat without
    physician order

134
Lice
  • Instruct patient/parent to
  • Remove nits
  • Soak hair with equal parts warm vinegar and water
  • If eyelashes or eyebrows, apply layer of
    petroleum jelly
  • Soak combs and brushes in pediculicide for 1 hour
  • Launder clothing/bedding in hot water dry in hot
    drier if possible, discard clothing and linen if
    practical

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Lice
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Lice
  • Instruct patient/parent to
  • Iron seams of clothing
  • Put socks over hands of small children at bedtime
  • Cut fingernails short
  • Put hats, coats, other non-launderable item away
    for at lest 72 hours
  • Avoid hat sharing, combs, brushes

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Skin infestations Scabies
  • Highly contagious by the itch mite Sarcoptes
    scabiei var hominis
  • Eggs are laid in burrows several millimeter in
    length
  • Not a vector for other infections
  • Transmitted by intimate personal or sexual
    contact or by casual contact
  • Always consider when patient complains of rash
    with intense itching

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Scabies
  • Assessment
  • Subjective data
  • History of current illness
  • Intense itching, worse at night
  • Rash
  • Previous treatment for current problem
  • Exposure to scabies
  • Medical history
  • Previous infestations
  • Allergies
  • medications

140
Scabies
  • Objective data
  • Physical exam
  • Rash
  • Red papules, excoriations, and occasionally
    vesicles
  • More common in interdigit web spaces, wrists,
    anterior axillary folds, periumbilical skin,
    pelvic girdle, penis, ankles
  • For infants and small children, soles, palms,
    face, neck, and scalp are often involved
  • Patient scratching
  • Signs of infection of lesions

141
Scabies
  • Interventions
  • Contact isolation
  • Advise patient/parent to avoid school/work until
    one treatment completed
  • Administer analgesics, antihistamines,
    antibiotics
  • Use pediculicides
  • Pyrethrin liquid
  • Permethrin crème

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Scabies
  • Instruct patient/parent
  • Instruct patient/parent that itching may continue
    after treatment do not re-treat without
    physician order
  • Launder clothing/bedding in hot water dry in hot
    drier if possible, discard clothing and linen if
    practical
  • Put socks over hands of small children at bedtime
  • Cut fingernails short
  • Put hats, coats, other non-launderable item away
    for at least 72 hours

143
Skin infestations myiasis
  • Invasion of living, necrotic, or dead tissue by
    fly larvae (maggots)
  • Do not carry infectious agents, but can cause
    significant disease of the tissues

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Skin infestations myiasis
  • Ability to care for self
  • Substance abuse
  • Previous myiasis
  • Medications
  • Allergies
  • Assessment
  • Subjective data
  • History of present illness
  • Skin lesions or wound
  • Social History
  • Living conditions

145
Myiasis
  • Objective data
  • Physical examination
  • Skin wound or lesion
  • Boil-like lesion
  • creeping eruption of open wounds
  • Poor hygiene may see maggots in skin folds or
    on intact skin surface

146
Myiasis
  • Interventions
  • Contact isolation
  • Advise patient/parent to avoid school/work until
    treatment completed
  • Administer analgesics and antibiotics
  • Prepare to assist with surgical debridement

147
Myiasis
  • Interventions
  • Apply petroleum jelly to cutaneous boils
  • Instruct patient about prevention
  • Eradicate flies
  • Keep open wounds properly dressed
  • Stay indoors, away from fly-infested areas
  • Referrals to Social Services or Substance Abuse
    if needed

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Tuberculosis
  • Mycobacterium tuberculosis, acid-fast bacillus
    (AFB)
  • Not highly contagious, requires close, frequent
    exposure for transmission
  • Droplet nuclei, which can remain in still air for
    days
  • Susceptibility of host usually determines whether
    infection occurs
  • TB occurs when symptoms occur and is infectious
  • 2-10 weeks after infection, develop immunological
    response, allows healing and PPD

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Tuberculosis
  • Greatest risk of disease in the first 2 years
    after infection
  • Lung primary site
  • 15 Extrapulmonary
  • Kidney, Lymphatic, Pleura, Bones, Joints, and
    blood (disseminated or miliary)
  • Diagnosed by one of two criteria
  • Culture of bacteria
  • PPD or SS of TB, unsteady CXR
  • Noncompliance of medication regimen

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Tuberculosis
  • Assessment
  • Subjective data
  • History of present illness
  • Exposure to TB
  • Productive prolonged cough
  • Longer than 2 weeks
  • Becoming progressively worse

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Tuberculosis
  • History of present illness
  • Fever and chills, night sweats
  • Easy fatigability and malaise
  • Anorexia, weight loss
  • Hemoptysis
  • Recent TB skin test
  • Foreign born or travel to high-prevalence
    country Vietnam, Philippines, Mexico, Haiti,
    China, Korea

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Tuberculosis
  • History of present illness
  • Resident or staff of nursing home, prison, or
    homeless shelter
  • Alcoholic or other substance
    abuser
  • Racial/ethnic minority
    African-American, Hispanic,
    Alaska native,
    American Indian

155
Tuberculosis
  • Medical History
  • DM
  • Malignancy
  • CRF
  • Immunosuppression
  • HIV and AIDS
  • Medications, especially prolonged steroid therapy
  • Allergies

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Tuberculosis
  • Objective data
  • Physical exam
  • Healthy or ill appearance
  • Chest decreased breath
  • sounds
  • Fever
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