Pendik Veterinary Control and Research Institute

1
Pendik VeterinaryControl and ResearchInstitute
Istanbul/Turkiye
2
(No Transcript)
3
History
The first bacteriology laboratory was founded in
the country in the name of Bakteriyolojihane-i
Osmani (Bacteriologyhouse of Ottoman) in 1894
under the management of Dr. Mourice Nicolle from
France.
4
In the same year cattle plague serum production
had been started. In 1912 institute was
transferred to its final location in
Pendik. During that period Barbon
(Pasteurellosis bubalorum) vaccine, Tuberculin
and Mallein had been started to production.
5
Following the proclamation of Turkish Republic,
the phase of improvements started in 1923. During
1949-1964 first contacts with FAO, pathology
laboratory founded, revolving fund
established. During 1965-2001 equipments updated
and institute magazine was established.
6
Responsibilities
Pendik Veterinary Control and Research Institute
is directly committed and works under Turkish
Ministry of Agriculture and Rural Affairs (MARA).
Pendik Inst. serves to 12 provinces in Trakya
and Marmara Regions in some parts of their duties
and serves to all country with the other duties
such as biological productions, diagnostics and
drug quality controls.
7
Provinces under the responsibility of the
Veterinary Control and Research Institutes  
8

• The institute continues in the fields of
  researches, diagnostics services, production,
  education, publishing, strategy and project
  development.
• With these studies institute has established
  bounds with organisations such as FAO, OIE, EU,
  VLA, IAEA, AFFSA, WHO-MZCC and developed common
  projects and strategies.

9
Organisation Schema
DIRECTOR
RESEARCH COMMITTEE
DEPUTY DIRECTOR TECHNICAL
DEPUTY DIRECTOR ADMINISTRATION
SUPPORT MANINTANENCE
SUPPORT MAINTENANCE
RESEARCH AND PUBLICITY COORDINATION
PERSONNEL
GENERAL BUDGET
REVOLVING FUND
INVENTORY
WAREHOUSE
SUPPORT MAINTENANCE

• VEHICLE
• SECURITY
• MANAGERIAL HEADQUARTER
• SHIPPING

PHARMACOLOGY DEPARTMENT
PRODUCTION DEPARTMENT
DIAGNOSTICS DEPARTMENT

• BACTERIOLOGICAL DIAGNOSTICS LAB.
• POULTRY DISEASES DIAGNOSTICS LAB.
• PATHOLOGY LAB.
• RABIES DIAGNOSTICS LAB.
• VIRAL DIAGNOSTICS LAB.
• SEROLOGICAL DIAGNOSTICS LAB.
• PARASITARY DIAGNOSTICS LAB.
• AQUA PRODUCTS AND FISH DISEASES DIAGNOSTICS LAB.
• MOLECULAR MICROBIOLOGY LAB.
• MYCOPLASMA REFERENCE DIAGNOSTICS LAB.
• SHEEP-GOAT POX REFERENCE DIAGNOSTICS LAB.
• THEILERIA ANNULATA REFERENCE DIAGNOSTICS LAB.
• ANAEROB REFERENCE DIAGNOSTICS LAB.
• EPIDEMIOLOGY STATISTICS UNIT
• SAMPLE RECEIVING UNIT

• ANAEROB PRODUCTION LAB.
• AEROB PRODUCTION LAB.
• VIRAL VACCINESPRODUCTION LAB.
• BRUCELLA PRODUCTION LAB.
• MYCOPLASMA PRODUCTION LAB.
• PARASITARY VACCINES PRODUCTION LAB.
• PRODUCTION CONTROL UNIT

• DRUG QUALITY CONTROL LAB.
• RESIDUE LAB.
• TOXICOLOGY LAB

10

• Pendik Inst. is now producing
• 17 vaccines
• 22 serums, antigen and biological materials.
• Right now Pendik Inst. continues to serve with
• 23 laboratories under 3 departments.

11
Organisation Schema

• Number of employees
• Dr. Vet. Med 24
• Vet. Med. 28
• Biologist, Chemist 6
• Enginer 3
• Technician 15
• Staff 24
• Worker 49

12
National References

• Sheep and Goat Pox
• Animal Brucellosis
• Animal Mycoplasmosis
• Anaerob Diseases
• Theileria annulata
• Mareks Diseases
• Residues (Chloramphenicol, nitrofuran etc)
• Avian Influenza

13
AVIAN INFLUENZA IN TURKEY
14
Avian Influenza outbreaks in Turkiye

• First occurence of Avian Influenza in Turkiye was
  defined on
• 5 October 2005 in province of Balikesir, Manyas
  district, Kiziksa town
• As a result of measures taken got under control.
  Progress was regularly reported to international
  organisations.

15

• Second outbreak was on 15 December 2005 from
  Igdir provinces Aralik district, in East
  Anatolia Region.
• H5N1 type of Avian Influenza was identified by
  National Reference laboratory on 26 December 2005
  and it was also confirmed by Weybridge-England
  which is EU reference laboratory as type H5N1 on
  07 January 2006.

16
Avian Influenza

• 25 December 2005 26 February 2007
• 247 confirmed cases
• 246 of which were of HPAI H5N1 virus
• 1 of which was of LPAI H7N1 virus.
• Amongst these outbreaks
• 217 outbreaks in domestic poultry
• - 216 were determined in backyard
  flocks
• - 1 was small scale commercial flock in
  Elazig
• 30 cases were determined in wildlife

17
Avian Influenza

• The latest confirmed wild bird case in February
  2006.
• The latest confirmed case in domestic poultry in
  February 2007.
• The most recent disease report that has led to a
  confirmed case was on 26 February 2007
• Notification OIE and EU

18
The disease was observed in 53 of the 81
provinces. 19 had one confirmed outbreak, 14
had 2 confirmed outbreaks.3 had more than 10
confirmed Samsun had around one quarter of the
national total of confirmed outbreaks, 59.
19
Confirmed cases of HPAI by domestic and wild bird
AZARBA
AZARBAIJAN

• Wild Birds,
• Domestic poultry

20

Avian influenza diagnosis During the Outbreaksin
Pendik Veterinary Control and Research Institute

• Poultry disease,
• Serology,
• Molecular Microbiology Laboratories
• work together in the field of diagnosis of avian
  influenza including H5N1.

21
PENDIK VETERINARY CONTROL AND RESEARCH
INSTITUTEAVIAN INFLUENZA DIAGNOSIS
(11.10.2005-07.04.2006)
TOTAL CASES TOTAL CASES TOTAL SAMPLES TOTAL SAMPLES NEGATIVES NEGATIVES POSITIVES POSITIVES
Domestic Wild Domestic Wild Domestic Wild Domestic Wild
812 594 1389 889 1320 880 69 9
1406 1406 2278 2278 2200 2200 78 78
58 ISOLATES 57 H5N1 1 H7N1
22
The European Unions Technical Assistance
Programme for Turkey  

• Technical Assistance To Avian Influenza
  Preparedness Response Project in Turkey
• TR 06.AI/SV

http//www.kkgm.gov.tr/TR_06_AI_SV_new/index.htm
This project is financed by the European Union
The Project is implemented by Conseil Santé SA
23
PROJECT PURPOSE

• Overall objective
• The overall objective of the project is to
  minimize the threat in Turkey posed to humans by
  Highly Pathogenic Avian Influenza (HPAI)
  infection in domestic poultry and other animals,
  to diminish the burden of disease and loss of
  productivity, and to improve influenza pandemic
  preparedness and the response to this and other
  infectious disease threats to humans.
• Project purpose
• The project purpose is to support MARA and MoH in
  policy and strategy development for AI
  preparedness control and strengthening the
  capabilities of Veterinary Services for effective
  and efficient AI disease control and eradication
  activities.

24
PROJECT PURPOSE

• Results to be achieved1. National strategy
  developed and regulatory framework improved2.
  Epidemiology studies and surveillance programmes
  improved and disease information systems
  upgraded3. Veterinary services strengthened and
  inter-institutional coordination improved4.
  Public awareness raised regarding good poultry
  keeping practices and bio-security measures.

25
BACKGROUND OF THE PROJECT

• Eight regional Veterinary Control and Research
  Institutes (VCRIs) provide laboratory services
  with the ability to achieve virus isolation.
  Three of them, Bornova, Pendik and Etlik
  institute AI laboratories in charge of virus
  identification. Bornova institute the national
  reference laboratory. They are equipped and
  competent to undertake a broad range of standard
  diagnostic HPAI tests and provide technical
  backstopping to the other 5 regional laboratories
  authorized for AI diagnostics. However the
  conditions of those three laboratories do not
  meet the required bio-safety standards. Therefore
  GDPC plans to upgrade them to BSL 3.

26
(No Transcript)
27
(No Transcript)
28

• Contact PVCRI
• Bati Mahallesi Ankara Cad.
• No1 34890
• Pendik/ISTANBUL
• Tel. [phone]
• Fax [phone]
• E-mailpendik_at_penvet.gov.tr
• Webhttp//www.penvet.gov.tr

29
Thank you