Multiple Sclerosis

1
Multiple Sclerosis

• Dr. Shamekh M. El-Shamy

2

• Definition

3
Multiple Sclerosis

• Aetiology
• 1)Auto-immune disease
• 2) Other old theories include ischaemia of the
  white matter.

4
What is Multiple Sclerosis?
5

• Precipitating factors
• 1- Pregnancy and labour.
• 2- Trauma.
• 3- Infections as common cold,influenza
• 4- Physical fatigue.
• 5- Emotional stress.
• 6- Surgery.

6
Clinical Picture
7
Motor System affection
8
Sensory System affection
9

• Cerebellar affection
• Autonomic disturbances

10
Investigations

• 1.C.S.F. Examinations

11

• 2.Cortical evoked responses

12

• 3. C.T. Scanning
• 4. Nuclear magnetic resonance (NMR)

13
Treatment

• 1- Avoid the precipitating factors.
• 2- Corticosteroids.
• 3- Immunosuppressive agents.
• 4- A well-balanced diet and high doses of
  vitamins, specially B1,136 and B12.
• 5- Symptomatic treatment.
• 6- Physiotherapy to maintain mobility and avoid
  contractures.

14

• Thank you