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Title: NUTRITION DURING THE FIRST YEAR OF LIFE


1
NUTRITION DURING THE FIRST YEAR OF LIFE
2
BREAST FEEDING
  • Definition Breastfeeding is infants nutrition
    during the first 4 6 months of life with human
    milk only.
  • Methods
  • breast feeding
  • bottle feeding with human pumped milk
  • with teaspoon
  • gavage

3
BREAST FEEDING
4
BREAST FEEDING
  • The mechanism of milk secretion  Endocrine
    factor - estrogens, - placental lactogen
    hormone.  Nervous factor

5
The mechanism of milk secretion
  • Endocrine factor  Prolactin controls the
    beginning and milk secretion.   In pregnancy
    actual ? ? ? h estrogen inhibits prolactin. 
    After removal of the placenta ? ? ? h estrogen
    prolactin acts freely ? lactation.  Estrogens
    through pituitary hormones (mamogeni factors 1
    and 2) determine changes in the mammary gland
    lactation.

6
The mechanism of milk secretion
  • Factor Nervous
  •  - reflex act by excitations from the nipple and
    areola  
  • - contribute to the formation and maintenance of
    milk secretion.

7
HUMAN MILK COMPOSITION
  • Mammary gland secretion - colostrum -
    transitional milk, - mature milk.Colostrum -
    lactation within 5 days after birth - opaque
    yellow liquid, - Ig richer in protein than human
    milk and mature.

8
Colostrum
  • Protein - varies between 27-41 g / l -
    diminishes as soon as the milk flow. 
    Immunoglobulins - initially very high, which
    decrease during the first days after birth. -
    90 of total Ig are IgA (Ac polio Anticoli,
    antistaphylococcal, anticoxakie).
  •   Action from colostrum (resistant to digestive
    enzymes) Ac secreted by the gut destroy
    pathogens in the digestive tract ? high degree of
    local immunity.

9
Colostrum
  • Colostrum is adapted to the needs of the newborn
    in the first days of life, with increased
    quantities of - lactoferrin - secretory
    IgA, - protein bound vitamin B12 - zinc -
    lipase, alpha-amylase, phosphatase, protease
    inhibitors - taurine

10
Colostrum
  • Carbohydrates - total of 55-60 g / l -
    proportion of lactose is small (37 g / l) -
    oligosaccharides (23g / l), promotes implantation
    of the newborn intestine of the Bacillus bifidus.

11
Colostrum
  • Total lipids - initial 30g / l, in conjunction
    with low activity of intestinal lipase n.b then
    increase their level - unsaturated fatty acids
    are essential especially those in large
    quantities and have a role in nervous system
    development.

12
Colostrum
  • Mineral salts - the amount of 3.9 g / l - the
    Na, P, Ca, Fe, Zn, Cu more in line with that of
    protein.Vitamins A, E, C, B12 are well
    represented in colostrum compared with mature
    milk.Caloric value 58 kcal/100ml.

13
BREAST FEEDING
14
Transitional milk
  • on the 6th and 10th postpartum, although
    biochemical and immunological changes continue
    until one month
  • -  decreases the protein, mineral salts, pH,- 
    increase the level of lipids and lactose.

15
Mature human milk (h.m.)
  • Water - 87.Total Protein - 10g / l  4g / l
    casein  6g / l of whey protein (lactalbumin and
    lactoglobulin)
  •   Human milk is a milk type albumin.

16
Mature human milk
  • Human casein
  •  - mammary gland synthesis of amino acids in the
    blood  three fractions (alpha, beta and kappa)
  •  - kappa - casein has a role in colonization of
    the intestinal bifidus Bacilus in breastfed
    infant.

17
Mature human milk
  • Proteins in whey  Alfalactalbumina - contains
    lactosintetaza, an enzyme involved in lactose
    synthesis
  •   Lactoferrin - glycoprotein capable of
    reversibly bind iron milk ? Fe absorption in the
    intestines and stomach. - iron chelator ?
    bacteriostatic action. - additional factor of
    protection against intestinal pathogens, with
    IgAs, Lactobacilus lysozyme and bifidus.

18
Mature human milk
  • Proteins in whey- Betalactoglobulina milk is
    absent ? human milk are nealergizant.- serum
    albumin ? ligand role for folate, vit. B12,
    tyrosine, zinc.
  • Immunoglobulins IgAs - agglutinate of food
    antigens, bacterial enterotoxins and viruses,
    blocking their adhesion to epithelial surfaces,-
    Ac containing anti E. coli, Shigella, Salmonella,
    Klebsiella, Coxackie, Echo, polio virus,
    hepatitis B and measles virus.

19
Mature human milk
  • Ig G and Ig M- small quantities in milk,-
    serum Ig does not differ structurally.Enzymes
    in human milk - a role in- digestion of milk
    components- antibiotic protection.Lysozyme-
    contribute to lysis of intestinal bacteria,-
    enhances antibody formation.

20
Mature human milk - Enzymes
  • Lipases have a role in digestion of human milk
    triglycerides.Alfaamilaza- catalyzes the
    hydrolysis of starch into maltose- pancreatic
    and intestinal amylase offset deficit in the
    infant.Proteases and protease inhibitors-
    greater amount compared with cow's milk-
    catalyzes the hydrolysis of proteins.

21
Mature human milk
  • Amino acidstaurine - a role in absorption of
    lipids and brain development.
  • Human milk proteins are absorbed and used by the
    infant with optimal efficiency.No physical or
    chemical process does not allow for similar
    proteins in human milk.

22
BREST FEEDING
23
Mature human milk
  • Carbohydrates - 70 g / l - lactose
    (beta-lactose - 60 g / l) - a source of
    galactose(cerebrozidelor composition of the
    brain)
  • - oligosaccharides (10 g / l) - role in the
    defense of non-specific antibiotic (promotes
    intestinal colonization with Lactobacilus
    bifidus).

24
Mature human milk
  • Lactobacilus bifidus - roles - causes
    acidification of the intestinal environment ?
    inhibits the growth of pathogens - anemic and
    antirickets (promotes absorption of Fe, Ca, vit.
    D and lipid) - synthesis of vitamins B and K.

25
Mature human milk
  • Lipids 36 - 40 g / l  fatty acids (FA), mono
    and polyunsaturated fats (oleic acid, palmitoleic
    and linoleic)  -over half of the total FA
    h.m.  - role in CNS maturation in the newborn
    period  triglycerides - report equally between
    unsaturated and saturated FA.

26
Mature human milk
  • Cholesterol and lecithin  large quantities h.m.
    than c.m.The presence of lipase in human
    milk - facilitates lipid hydrolysis - FA
    promote rapid release of usable energy
    metabolism.

27
Mature human milk
  • Mineral salts and trace elements- content four
    times lower than c.m., less influenced by
    maternal dietary intake, being provided by
    maternal stores.
  • - thus, if sufficient phosphorus and calcium are
    the mother's diet, they are obtained through its
    mobilization from bone deposits.

28
Mature human milk
  • Sodium ? low amount of renal function
    overloading is avoided.Calcium four times and
    phosphorus 6-7 times less than the c.m., but the
    Ca P 2 1 is favorable for their proper
    use.Iron - amount of two times higher in
    h.m. - intestinal absorption and incorporation
    into the hemoglobin molecule is much higher in
    infants breastfed.

29
Mature human milk
  • Vitamins  soluble (A, D, E, K)  soluble (C,
    folic acid, vitamin complex. B)  - varying
    proportions, in relation to food intake.  - a
    balanced diet of the mother provides adequate
    intake of these vitamins, except vitamin D.

30
Mature human milk
  • The amount of vitamin D in human milk does not
    provide even if your baby needs a proper sun
    exposure, but is higher than that of cow's milk,
    which explains the lower incidence of rickets in
    infants breastfed.The energy value of h.m.
    mature 65-68 kcal/100ml.

31
BREAST FEEDING
32
Factors of human milk
  • 1. Antiinfectious protection factors -
    immunological - biological - provide
    protection against infectious agents from the
    environment until the baby develops its own
    immunity. 
  • breastfed infants versus artificially fed
    infants
  • -low rate of hospitalization-low incidence of
    respiratory infections, diarrhea, a rash, etc.
    sites.

33
Factors of human milk Antiinfectious protection
factors
  • Cellular factors (macrophages, neutrophils, Ly B
    and T)  anti-infective role in maternal mammary
    gland and infant's digestive tract (protects
    against enterocolitis ulceronecrotics). 
    Immunoglobulins - IgAs - opsonizant role, -
    mobilize and agglutinate bacteria, viruses and
    antigens of food,  Ly stimulates the formation
    of intestinal mucosal IgA in the infant.

34
Factors of human milk Antiinfectious protection
factors
  • Lactoferrin - bacteriostatic role.  Lysozyme -
    a role in combination with complement and
    antimicrobial IgAs, which potentiates the
    action.  Lactoperoxidase - bactericidal action
    against germs like Pseudomonas, E. coli,
    Salmonella, Streptococcus.

35
Factors of human milk Antiinfectious protection
factors
  • Mucin - prevent adhesion of germs and
    rotaviruses to the surface of intestine.  C3
    and C4 fractions of complement - role in
    chemoattraction of phagocytes and intracellular
    incorporation of particles.  Bifidogens factors
    (glycoproteins and oligosaccharides) - role in
    promoting growth of Lactobacilus bifidus in the
    intestine of breastfed infant.

36
Factors of human milk
  • 2. Modulators of growth factors- stimulates
    growth of mammary gland- acting on the baby's
    organs.   Epidermal growth factor (epidermal
    GrowthFactor - EGF) and insulin-like growth
    factor (Insulin-like growth factor IGF-1) - role
    in the maturation of the gastrointestinal tract.

37
Factors of human milk Modulators of growth
factors
  • Nervous growth factor - essential for the
    development of sympathetic neurons and sensory
    cells.  B-cell stimulating factor - role in the
    proliferation of Ly B and production of
    immunoglobulins.  Taurine - improves fat
    absorption and promotes intestinal colonization
    of Lactobacilus bifidus.

38
Breast feeding
39
Other qualities of human milk
  • - is always fresh and available (immediately
    available) - does not involve special training
    (breast care is required) - is the ideal
    temperature - is aseptically - not cause
    allergies or intolerance - has an optimum power
    distribution, the total energy being supplied by
    fat (55), carbohydrates (38) and protein (7).

40
Evolution of milk secretion
  • "Anger milk" colostrum transformation in
    transition milk and then mature h.m.Clinical
    Manifestations  turgescence of mammary glands
    pain, local hyperthermia,  fever, headache,
    tachycardia.Paraclinical leukocytosis with
    lymphocytosis and eosinophilia.

41
Evolution of milk secretion
  • "Psychosis lactation" mental status changes
    that mayup to manic states - depression.-
    these phenomena disappear spontaneously in most
    cases.- mothers rarely requires admission to
    psychiatric hospitals.

42
Evolution of milk secretion
  • Maximum intensity of milk secretion - between
    day 15 and 3 months after birth - may take a
    year or more, if stimulated by sucking or
    squeezing the breast.Composition of human milk
    varies - according to the stages of
    lactation - after the time of day (diurnal
    variations / nocturnal) - from one breast to
    another, - the same breast over the meal.

43
Evolution of milk secretion
  • At the same table at the end of meal milk
    (hindmilk ) is richer in fat and protein than
    that of the beginning of the meal ("foremilk"),
    so it's hearty and nourishing.Administration
    only h.m. after the age of 6 months is not
    sufficient quantity and quality for infant
    development.

44
Factors influencing lactation
  • - age young women ? more abundant milk
    secretion-  parity primiparous lactation to be
    installed with a delay of several days - kinds
    of birth interventions from birth (cesarean,
    forceps, perineorafie) by trauma and
    postoperative diet are important factors in milk
    secretion inhibitors - feeding, resting, graded
    exercise and especially psychological factor
    contributing to maintaining a good milk secretion

45
Milk secretion
  • Stimulation of milk secretion - sucking -
    mammary gland drained, - ensuring physical
    comfort of the mother.Agalactic extremely
    rare.Hipogalactic more common in primiparous,
    the intellectual, women who do not comply with
    resting.Spontaneous flow of milk secretion this
    may be a sign of hipogalactic.

46
Benefits of breast feeding
  • Benefits for children - optimal growth and
    physical development - h.m. has all the nutrients
    needed, in quantities and proportions ideal for a
    child's needs and maximum bioavailability -
    mother - child bonding - solid and sustainable
    with long-term consequences of child mental
    health.

47
Benefits of breast feeding Benefits for children
  • low morbidity by-  much lower risk of
    malnutrition, acute diarrheal diseases,
    intestinal parasites, dental disease (caries,
    malocclusion, periodontal disease) - incidence
    lower than 50 of the malignant process during
    0-16 years - respiratory and ENT pathology
    rarer and less serious

48
Benefits of breast feeding Benefits for children
  • low morbidity by  - allergic asthma and
    different more rare and mild forms  - diabetes
    mellitus and risk of sudden death in infants less
    than 2-3 times  -urinary infections 5 times
    more rare in the first 6 months of life -
    protective role against hypertension and
    ateromatosis.

49
Benefits of breast feeding
  • Benefits for the mother - affective
    (psycho-emotional)
  •  - direct physical contact (skin to skin ")
    parent - child positive emotional reactions ? ?
    risk of abuse, neglect or mistreatment of
    children and ? risk of postpartum depression

50
Benefits of breast feeding Benefits for the
mother
  • - contraception ? tasks spacing ? effects on
    reproductive health of the mother - decreases
    the risk of breast cancer, ovary cancer - a
    lower incidence of osteoporosis is whether breast
    lasted more than nine months.

51
Benefits of breast feeding
  • 3. Family Benefits  fed infant develops
    smoothly, thus representing an emotional bond for
    the family  economic - to avoid the high
    costs, concerns and loss of time for preparation
    of milk, saves heat, detergents, etc..

52
Benefits of breast feeding Benefits for the
family
  • - fewer illnesses ? fewer doctor visits, fewer
    treatments - increased comfort - no need to
    purchase travel, training maneuvers,
    sterilization, contamination risks, egs..

53
Breast feeding
54
Incidents and complications in breastfeeding
  • Regurgitation - appears at the end of the meal,
    when eructation - should not be confused with
    vomiting - small quantity of milk is eliminated
    without running and does not affect the weight
    curve - not occur during sleep - is isolated,
    transient, without concomitant symptoms, -
    resolve spontaneously in the 2nd semester.

55
Incidents and complications in breastfeeding
  • Diarrhea (post) prandial diarrhea driving, the
    irritable bowel syndrome n.b. and infant
    breastfeeding. - is not a gastroenteritis -
    semi-emission chairs, yellow, acid, during the
    feeding or immediately after meal, often
    accompanied by screaming, agitation - can cause
    nappy rash - weight curve remains upward -
    general condition is good.

56
Incidents and complications in breastfeeding
  • Diarrhea (post) prandial - source of anxiety
    for the mother and family ? medical
    consultations, antibiotics unnecessarily -
    breast milk diet will not be interrupted - may
    recommend taking calcium carbonate, 0.5 - 1g/zi
    prior to administration of milk.

57
Incidents and complications in breastfeeding
  • Jaundice - early form (early onset
    breast-feeding jaundice") - appears in the first
    week of life - late-onset form - start by end
    of first week of life

58
Incidents and complications in breastfeeding
  • Early-onset jaundicemilk intake ? ? relative
    starvation ? ? bilirubinPreventing the rise of
    physiological jaundice  - breastfeeding, early
    and frequent  - temporarily supplement the diet
    with formula milk.

59
Incidents and complications in breastfeeding
  • Late-onset jaundice - 4th - 7th day of life,
    peak in the 3rd week and persists until 10
    weeks - unconjugated hyperbilirubinemia (BI) -
    absence of other signs of disease.
  • Diagnostic tests and therapeutic - BI values ?
    quickly, within days, if you stop feeding with
    h.m. and ? to resume. - Breastfeeding is
    recommended to further phenobarbital few days.

60
Incidents and complications in breastfeeding
  • Hipogalactia tongue - rarely primary - often
    secondary, related physical, mental, maternal
    diet and poor food technique.The child does not
    increase weight is stirring (hungry), is rare
    stools and dark, then gets drowsy and have signs
    of dehydration.

61
Incident and complications in breastfeeding
  • Mastitis and breast abscess
  • - consequence of milk stasis and breast small
    cracks,
  • - occurring as a result of inadequate sucking.

62
Obstacles in breast feeding
  • From the child - malformations of the oral
    cavity (lip rabbit, wolf's mouth,
    retrognathic) - infections (rhinitis, otitis,
    pneumonia) - neurological diseases
    (meningocerebral bleeding, meningitis,
    encephalitis)

63
Obstacles in breast feeding
  • From the child- prematurity - haemolytic
    disease of the newborn - jaundice - vomiting
    .

64
Obstacles in breast feeding
  • From the mother - anger milk - temporary
    hypogalactia - inverted nipples - abrasions
    of the nipple  - lymphangitis, mastitis

65
Permanent contraindications
  • Maternal factors - severe progressive visceral
    disease tuberculosis, hepatitis, AIDS, malaria,
    septicemia, cancer / chemotherapy treatment,
    heart failure, renal failure - neuropsyhic
    disease severe mental disorder / psychosis of
    lactation, multiple sclerosis, epilepsy /
    anticonvulsant therapy - other situations /
    diseases diabetes mellitus, a new task with agegt
    20 weeks.

66
Permanent contraindications
  • Child - related cases (rare, some even
    exceptional)
  •  - congenital galactosemia
  •  - hereditary / primary intolerance to lactose
  •  - phenylketonuria.

67
Supliments required during breast feeding
  • The child  - vitamin D (rickets prophylaxis) 
    - iron (oral preparations)
  •   infants born at term  1-2 mg elemental Fe /
    kg / day from the age of 5-6 months (for 3
    months).  premature  2 to 2.5 mg elemental Fe
    / kg / day, from 1 ½ - 3 months to 1 year of age.
  • Iron injection are contraindicated.

68
Supliments required during breast feeding
  • The childIn general, while being breast fed, no
    extra fluid intake needed (water / tea, fruit
    juice, etc..), especially in newborn and small
    infant.New born at term, healthy weight with a
    constant upward curve does not need anything
    other than human milk.

69
Supliments required during breast feeding
  • Mother - for lactation - extra calories -
    avoid consumption of alcohol - avoid strong
    smelling foods (onions, garlic, spices) and those
    rich in cellulose (peas, beans, cabbage) that can
    give diarrhea in children - avoid canned.

70
Supliments required during breast feeding
  • Vegetarian Mothers
  •  - will consume milk daily
  •  - will supplement the diet with vitamin B12
    which is found almost exclusively in animal
    products.

71
Weaning
  • Will be made as late as possible.
  • There are considerable advantages to provide even
    small amounts of h.m until the age of 1 year, 1
    ½, even 2 years.

72
BOTTLE FEEDING
73
BOTTLE FEEDING
  • Definition bottle feeding is infants nutrition
    during the first 4 months of life with other milk
    than human milk.  The recommended industrial
    preparations are made of cow's milk because the
    process they tend to be as close is possible to
    h.m
  •   The administration will use cow milk only when
    it is absolutely impossible to use formula milk.

74
The composition of cow's milk (c.m)
  • Protein 32-34 g / l casein - 28 g (lv casein is
    a milk type) whey protein (lactalbumin and
    lactoglobulin) 4-6 g.ß-lactglobulin is highly
    antigenic / allergy.Casein c.m precipitates in
    the stomach of infants in large clots, difficult
    digestible ? longer intervals of time between
    lunches.

75
The composition of cow's milk
  • Carbohydrates 48-50 g / l (vs. 68-70 g / l
    h.m)  represented only lactose ? low intake of
    galactose ? slow myelination of CNS. 
    oligosaccharides missing ? absence of bowel
    colonization with bacillus bifidus in bottle fed
    infant

76
The composition of cow's milk
  • Lipids 36 g / l - saturated, indigestible,
    deficient in essential fatty acids - five times
    lower amount of linoleic acid - cholesterol in
    amounts less than h.m

77
The composition of cow's milk
  • Mineral salts - amount of four times higher
    than in h.m.  with high protein content ?
    metabolites and osmolarity ? ? ? ? baby's water
    needs. - amounts of phosphate and citrate ? ? ?
    pH gastric ? prevents absorption and promotes Ca
    elimination

78
The composition of cow's milk Mineral salts
  • The ratio Ca / P 1
  • - inappropriate for absorption - rickety -
    putrefaction (intestinal flora - E. coli)  ?
    effort to remove the liver and kidney
    metabolites.

79
The composition of cow's milk
  • Iron  Fe deficiency l.v. explains its poor
    absorption frequency and iron deficiency anemia
    in infants fed cow's milk.Vitamins - smaller
    quantities than in human milk and by boiling the
    milk a good part of them are destroyed.

80
Disadvantages administration of cow milk
  • - iron deficiency, the intake / absorption low
    intestinal absorption (occult bleeding) due
    allergenicity of cow's milk - various
    nutritional deficiencies (rickets, etc.) -
    dehydration through increased renal load -
    increased risk to allergy.

81
COWS MILK PROTEIN ALLERGY
  • Definition hypersensitivity reaction caused by
    any of the protein components of c.m (most likely
    ß lactoglobulin).Allergic reaction
  •  - immediate - mediated IgE - delayed -
    mediated cell.

82
COWS MILK PROTEIN ALLERGY
  • Clinical Manifestations - leather (infant
    eczema, allergic first manifestation) -
    digestive system (vomiting, diarrhea, colic, poor
    growth, RGE, chronic constipation) - respirator
    (recurrent wheezing).Hint iron deficiency
    anemia (occult gastrointestinal bleeding).

83
COWS MILK PROTEIN ALLERGY
  • The most important diagnostic test used in
    therapeutic practice (investigations infant
    allergy is hard)is removal of the feeding of cow
    milk and cow milk 's derivatives ? improvement of
    symptoms.Drug treatment is not necessary.Just
    replace c.m with a hypoallergenic formula milk.
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