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Title: Medical-Surgical


1
Medical-Surgical
  • Musculo-Skeletal System Disorders

2
Review of Musculo-Skeletal System Anatomy and
Physiology
  • Bone hard tissue that makes up most of the
    skeletal system.
  • Functions 1. support
  • 2. protection
  • 3. movement
  • 4. storage of calcium and
  • other ions
  • 5. manufacture of blood
    cells

3
Cartilage
  • Specialized fibrous connective tissue.
  • It provides firm but flexible support for the
    embryonic skeleton and part of the adult skeleton
  • Differs from bone in that its matrix has the
    consistency of a firm plastic or gristle-like
    gel.
  • Cartilage cells are called chondrocytes and are
    located in tiny spaces that are distributed
    throughout the matrix.

4
Terminologies
  • Acrosclerosis
  • Amputation
  • Ankylosis
  • Arthritis
  • Arthrocentesis
  • Arthrogram
  • Arthroplasty
  • Arthroscopy
  • Bursitis
  • Cast
  • Dislocation
  • Electromyogram
  • Fasciotomy
  • Fracture
  • Gangrene
  • Gout
  • Halo Device
  • Kyphosis
  • Laminectomy

5
Terminologies
  • Lordosis
  • Myelogram
  • Orthopedics
  • Osteomalacia
  • Osteomyelitis
  • Prosthesis
  • Replantation
  • Rickets
  • Sclerodactyly
  • Scoliosis
  • Sequestration
  • Skeletal Traction
  • Spinal Stenosis
  • Sprain
  • Strain
  • Synovectomy
  • Tenosynovitis

6
Acronyms
  • AEA
  • AKA
  • BEA
  • BKA
  • CK
  • CMS
  • CPM
  • DJD
  • ECG
  • EEG
  • ESR
  • HNP
  • IVD
  • OA
  • ORIF
  • RA
  • RF
  • SLE
  • THA
  • TMJ
  • TLSO

7
Joint Structure and Function
  • Connective tissue disorders are often manifested
    as joint disorders since joint mobility is
    dependent on functional connective tissues.
  • Joint is the site at which two or more bones of
    the body are joined.
  • Joint permits motion and flexibility of the rigid
    bone
  • Hyoid bone the only bone in the human body that
    does not articulate with at least one other bone,
    to which the tongue is attached.

8
Ligaments
  • Are strong and flexible fibrous bands of
    connective tissue that connect bones and
    cartilage and support muscles.
  • Yellow ligaments and white ligaments have
    distinctively different functions.
  • Yellow ligaments, located in the vertebral
    column, are elastic and allow for stretching.
  • White ligaments, found in the knee, do not
    stretch but provide stability.

9
Joint Structure and Function
  • Classification on basis of the extent of
    movements
  • Synarthroses fixed joints
  • ex. Skull allow no movement at all
  • Amphiarthroses slightly movable joints
  • ex. Juncture of the ulna and radius in the
  • forearm.
  • Diarthroses freely movable joints
  • ex. Elbows, shoulders, fingers, hips, and
    knees.
  • sometimes called synovial joints. They are
  • encased in a fibrous capsule made of strong
    cartilage and lined with synovial membrane

10
Tendons
  • Are composed of very strong and dense fibrous
    connective tissue.
  • They are in the shape of heavy cords and anchor
    muscles firmly to bones.
  • Achilles tendon, one of the most prominent tendon
    which can be felt at the back of the ankle just
    above the heel.

11
Joint Structure and Function
  • Synovial membrane is very smooth, thus permitting
    structures to move without friction.
  • Ligaments are tough fibrous cords that bind the
    capsule.
  • Synovial fluids fills and lubricates the space in
    the middle of the joint.
  • Bursae permit tendons to sl,ide easily with
    movement of the bones.

12
Definition of Terms
  • Orthopedics specialty of medicine that examines
    and treats diseases and injuries of the
    musculoskeletal system.
  • Orthopedists- Surgeon who specialize in the area
    of orthopedics.
  • Orthopedic nursing involves preventing further
    complications for clients with musculoskeletal
    conditions.

13
Common Diagnostic Tests Related to
Musculo-Skeletal Disorders
  • Diagnostic Tests nursing clients with
    musculoskeletal disorders is likely to involve
    preparation for physical examination,
    radiographic tests, and other diagnostic
    procedures.
  • Be sure to explain the actual procedures to
    reduce tension or anxiety that clients may
    experience.

14
Laboratory Test
  • Diagnostic Studies for Diagnosing Connective
    Tissue Disorder.
  • Studies help to determine whether a disorder is
    inflammatory or non-inflammatory.
  • Complete Blood Cell ( CBC) Count
  • - identifies the total number of blood cells
  • (WBCs, RBCs and platelets as well as
  • hemoglobin (Hgb) and hematocrit (Hct),
  • percentage of blood consisting of RBCs
  • and RBC indices.
  • WBC Count increase in infection, tissue
  • necrosis, inflammation, may decrease in
    SLE.
  • RBC Count detects and differentiates
    blood
  • dyscrasias. Decreased in RA and SLE.

15
Laboratory Test
  • Erythrocyte Sedimentation Rate (ESR) Determines
    presence of inflammation as
  • in Rheumatoid Arthritis (RA), Rheumatic
  • Fever, and decreased with osteoarthritis.
  • Fasting not required. Apply pressure to
    venipuncture site. Assess
  • site for bleeding
  • C- Reactive Protein Determination
  • - Detects active inflammation as in RA and
  • disseminated lupus erythematosus.
  • Restrict food and fluids for 4 hours.
  • Apply pressure to venipuncture site. Assess
  • site for bleeding

16
Laboratory Test
  • Venereal Disease Research Laboratory
  • (VDRL) Measures antibodies to syphilis.
  • Sometimes decrease in SLE. Fasting not
  • required. Apply pressure to venipucture
  • site. Assess for bleeding.
  • Rheumatoid Factor ( RF) Detects antibodies
    often present with RA. Fasting not required.
    Apply pressure to venipucture
  • site. Assess for bleeding.

17
Laboratory Test
  • Antinuclear Antibodies (ANA) Positive in SLE,
    systemic sclerosis, Reynauds disease, Sjorens
    sysndrome, and necrotizing arteritis. Fast for 8
    hours. Apply pressure to venipuncture site.
    Assess site for bleeding.
  • Creatinine- Assesses renal function. Increase
    with SLE, PSS, polyarthritis. Fasting not
    required. Apply pressure to venipuncture site.
    Assess site for bleeding.

18
Laboratory Test
  • Urine maybe tested also for creatinine and uric
    acid level.
  • 24- Hour Urine Creatinine
  • - Measures renal function and status of
    muscles diseases. Instruct the patient to collect
    a 24-hour urine specimen.
  • Urinary Uric Acid ( 24-Hour Collection).
  • - Measures uric acid metabolism increase in
    gout, liver disease, chronic myelogenous
    leukemia, fever.
  • Requires a 24-hour urine specimen.

19
Radiologic Studies
  • Arthrography Use contrast medium to show
    soft-tissue joint structures. Question patient
    about allergy to contrast agent, seafood, iodine.
    Tell patient that needle insertion may cause
    swelling that last several days. Assess and
    document discomfort, swelling. Instruct patient
    to avoid strenuous activity 12-24 hr. after test.
    Joint may be wrapped.

20
Computed Tomography (CT)
  • Detec tumors and some spinal fractures.
  • Tell patient that procedure may be lengthy
  • (up to 30 min per body part). Patient lies on
    a stretcher while a machine scans area being
    studied. No post procedure nursing care required.
  • Diskography
  • Visualizes vertebral disk after contrast medium
    injected into disk. Preparation and post nursing
    care is same as in arthrography

21
Magnetic Resonance Imaging
  • Visualizes soft tissue. May detect avascular
    necrosis , disk disease, tumors, osteomyelitis,
    and torn ligaments.
  • - tell the patient the procedure is painless
  • must lie still for 30 min. or more . Some
  • equipment has videos that patient can
  • view to reduce anxiety. Ask whether patient
    is
  • claustrophobic. Give sedation if ordered for
    agitated or anxious patients. Remove any
    metallic object such as jewelry. Inquire whether
    patient has any implanted devices such as cardiac
    pacemaker or intracranial aneurysm clips and
    notify radiologist. Procedure is contraindicated
    with some implants. Metal may not a problem with
    some newer equipment. No post procedure care
    requires. Safety is needed is sedated.

22
Nuclear Scintigraphy (Bone Scan)
  • Detects bone malignancies, osteoporosis,
    osteomyelitis and some fractures.
  • Contraindicated during pregnancy. Tell patient
    that a small amount of radioactive
  • material will be injected intravenously, then
    a scanner will move slowly back and forth over
    the body as the patient lies on a stretcher . May
    take 1 hour procedure is painless except for
    venipuncture. Radioactive isotopes are not
    harmful except to fetus. Empty bladder
    immediately before procedure for comfort and
    prevent blocked view of pelvis.

23
Common Diagnostic Tests Related to
Musculo-Skeletal Disorders
  • Radiography (X-Ray)
  • - is the most common method of assessing the
    general state of the bone.
  • - non-invasively visualizes bones and other
    internal structures, so that health care provider
    can diagnosed abnormalities and monitor the
    effectiveness of treatments.
  • - Some types of radiographic exams requires use
    of radiographic dyes

24
Radiography
  • Shows density, texture, and alignments of bones
    reveals soft tissue involvement. Tell patient to
    expect to lie on an X-ray table or to stand next
    to a special device while films are taken. Remove
    any radiopaque objects ( jewelry, etc.), that can
    interfere with results. Advise radiology of
    patients physical limitations r/t moving,
    turning, climbing.

25
Tomography
  • Provides details of structure otherwise hidden by
    bone.Requires lying in a cylindric scannerassess
    for claustrophobia and inform radiologist.
  • Ultrasonography
  • - reveals masses or fluid in soft tissue.
  • Arthroscopy
  • - A surgical procedure to visualize a joint
    cavity and structure and to obtain fluid and/or
    tissue for study. Inform patient that procedure
    is performed in operating room under local or
    general anesthesia.

26
Arthrogram
  • X-Ray study of the joint ( e.g. Knee or shoulder)
  • Radiopaque or radiolucent substance is injected,
    and then a sequence of x-rays is taken to
    determine the joints condition.
  • Myelogram
  • Is an x-ray examination of the spinal cord and
    vertebral canal after injection of a contrast
    medium or air into the spinal sub-arachnoid
    space. Valuable in evaluating spinal cord
    abnormalities cause by tumors, herniated
    intervertebral disk, or other lesions.

27
Ultrasound
  • Uses sound waves and their echos to display
    images helps to evaluates soft tissue masses,
    osteomyelitis, infection, congenital and acquired
    pediatric disorders, bone mineral density, sports
    injuries, and fracture healing.
  • Non-invasive, inexpensive, readily available, and
    safe because it does not involve ionizing
    radiation.

28
Arthrocentesis
  • Aspiration of synovial fluid, blood, or pus from
    a joint cavity. By examining these fluids, a
    health care provider can diagnosed infections,
    inflammatory conditions and bleeding
  • Compression dressing is a joint after the
    procedure and the joint is rested for 1 day.

29
Arthroscopy
  • Invasive procedure using specialized endoscope
    design to view joints.
  • Use tiny incision known as stab wound.
  • It is a close procedure.
  • Performed in OR or same day surgery often under
    local anesthesia.
  • Arthroscopy use to diagnosed and treat joint
    disorders.
  • E.g. Foreign or loose objects ( piece of
    cartilage or a bone spur can be removed.
  • Rough and worn joint can be made smoother and
    more comfortable.
  • Tissue samples can be obtained for biopsy.
  • Torn meniscus or ligament can be diagnosed and
    possibly repaired.
  • Much safer, more comfortable, and more cost
    effective than open surgery.
  • Post procedure, elevate clients joint and apply
    ice to control edema and pain. Teach client to
    monitor for s/s of infection.

30
Biopsy
  • Biopsy of bone, tissue, or muscle must be
    performed using local anesthesia to diagnose
    tumors, infections, muscle inflammation or
    arthophy and various other problems.
  • Post procedure , monitor site for bleeding,
    swelling, infection or hematoma.

31
Electromyogram (EMG)
  • Test of electrical conductivity, similar to ECG
    or the EEG. Provider places fine needles into the
    clients muscle and measures the electrical
    impulses within the muscle, both at rest and
    during activity. The provider can then determine
    whether or not the clients muscle respond
    appropriately to stimuli.

32
Commom Medical Treatments
  • Joint, bone and muscle disorders often cause pain
    and limit movement.
  • Common treatments include
  • - Heat application e.g. hot soaks or baths
  • paraffin baths.
  • - Cold application e.g. cold compress or packs
  • Physical Therapy PROM and AROM
  • Massage if joints are not damage or inflamed,
    often helps to soothe aching joints.
  • External immobilization braces, corsets,
    splints, cast and traction.

33
Common Surgical treatments
  • Performed to remove or repair damaged or diseased
    parts.
  • Disorders that require surgery include
  • fractures, ligament ruptures, arthritic
    joints, or accidental limb amputation
  • Surgery necessary when fractured joint or bone
    cannot heal with external fixation.
  • Fracture resulting to multiple fragments using
    surgical hardware such as pins, screws, or plates

34
Example of surgery
  • Common treatment for client with either arthritis
    or severe fractures that may not heal.
  • - Joint replacement surgery
  • - Arthroplasty
  • Amputation surgical choice if a limb is damage by
    injury or disease beyond repair.

35
Common Therapeutic Measures
  • Splint, Cast and Immobilizers
  • Use to secure the position of the body parts
    being treated.
  • Hold the bone in alignment while allowing enough
    movement for other parts of the body to carry
    out activities of daily living.
  • Cast- is a solid mold that is used to immobilized
    a fracture can be made of plaster of Paris,
    fiberglass, thermoplastic resins, thermolabile
    plastic and polyester-cotton knit impregnated
    with polyurethane.

36
Common Therapeutic Measures
  • Plaster of Paris anhydrous calcium sulfate
    embedded in gauze. Least expensive type of cast
    used.
  • Dries after about 24 to 72 hours depending on the
    size and location.
  • Can withstand weight-bearing and other stresses
    as long as dry and strong.
  • Petaling short pieces of tape placed over the
    edges of the cast to prevent skin irritation by
    rough edges and to protect the cast from moisture
    and soiling.

37
Cast fiberglass
  • is a synthetic material used for cast that is
    lighter and has shorter drying time than plaster
    of Paris.
  • Drying time 10 -15 minutes, and can stand
    weight-bearing 30 minutes after application.
  • Cast split down the front to allow the casting
    material and padding to spread.
  • Bivalved cast is cut down both sides so that the
    front portion can be removed while the back
    portion maintain immobilization.
  • Windowed cast opening is cut into the cast to
    allow inspection of the body area or to relieve
    pressure. Cut out window need to be saved.

38
4 main groups of cast
  • Upper extremity cast use for breaks in the
    shoulder, arm, wrist and hand. Wearing an arm
    cast should keep the arm elevated above the heart
    when lying in bed to prevent swelling. Arm is
    kept in a sling for support when the patient is
    up.
  • Lower extremity- used for breaks in the upper and
    lower leg, ankle and foot. A leg cast is used to
    allow mobility and maybe used with crutches.
    Affected leg should be elevated on several
    pillows during the first few days after the break
    to prevent swelling.
  • Cast brace supports the affected part while
    allowing the knee to bend . Applying a cast above
    and below the knee and connecting them with
    hinge.

39
Body or spica cast
  • Used when a fracture is located somewhere in the
    trunk of the body. The body cast encircles the
    trunk , whereas a spica cast encase the trunk
    plus one or two extremities.
  • Body or spica cast severely limit mobility and
    may cause complications related to lack of
    movement such as skin breakdown, respiratory
    problem, constipation, and joint contractures.

40
Cast Syndrome
  • It is cause by compression of a portion of the
    duodenum between the superior mesenteric artery
    and the aorta and vertebral column.
  • Sign and symptoms
  • - nausea
  • - abdominal distention

41
Facts
  • Cast is removed only on physicians order.
  • Cast cutter use to cut the plaster
  • Skin under the cast will be noted tender and dry
    and may have crust of dry skin.
  • Gently wash the areaand explain that the skin
    will regain its normal appearance after few days.
  • Muscle atrophy may be apparent. Assure the
    patient that muscle mass will be restored with
    use of limb.

42
Patient teaching plan ( Cast Care)
  • Keep plaster cast dry follow physicians
    instructions regarding wetting synthetic cast.
  • Do not remove any padding.
  • Do not insert any foreign object inside the
  • cast.
  • Do not bear weight on a new plaster cast for 48
    hours ( synthetic , less than an hour.)
  • Do not cover the cast with plastic for prolonged
    periods.
  • Do report swelling, discoloration of toes or
    fingers, pain during motion, and burning or
    tingling under the cast to health care provider.

43
Traction
  • Exerts a pulling force on a fracture extremity to
    provide alignment of the broken bone fragments.
  • It is also use to correct deformity, decrease
    muscle spasm, promote rest, and maintain the
    position of the diseased or injured part.
  • Applied directly to skin ( skin traction)
  • Attached directly to the bone ( skeletal
    traction) by means of metal pin or wire.

44
Skin Traction
  • Weight is no more than 5 to 10 lbs to prevent
    injury to the skin.
  • Bucks traction used for hip and knee
    contractures, muscles spasms, and alignment of
    hip fractures.
  • Skeletal Traction
  • provides a strong, steady, continuous pull and
    can be used for prolonged periods of time.
  • e.g. Gardner-Wells, Crutchfield, and Vinke tongs
    and a halo vest, in which pins are inserted into
    the skull on either side. Heavier weights can be
    used with skeletal traction , usually from 15
    30 lbs.
  • Cruthcfield traction and a halo vest are used
    for reduction and immobilization of fractures of
    the cervical or high thoracic vertebrae.

45
Complication of tractions
  • Impaired circulation
  • Inadequate fracture alignment
  • Skin breakdown
  • Soft tissue injury
  • Pin track infection and osteomyelitis can occur

46
Important points to remember when patients are in
traction
  • Weights always hangs freely.
  • Be sure the amount of weight used is correct as
    ordered, clamps are tight, and ropes moves freely
    over pulleys.
  • Maintain good body alignments so the line of pull
    is correct.
  • Use padding to prevent trauma to skin where
    traction is applied. Report skin breakdown or
    irritation to the physician
  • Assess affected extremities for temperature,
    pain, sensation, motion, capillary refill time
    and pulses.
  • With skeletal traction, assess pin sites for
    redness, drainage, or odor which may indicate
    infection.

47
Application of Nursing Process on MS Disorders
  • Data collection
  • Assess for skeletal
  • deformity, and body build, note for asymetry,
    or deformity.
  • Palpate soft tissues, joints and muscles.
  • Assess skin temperature and document any
    swelling, crepitation, tenderness, or other
    abnormality.
  • Evaluate the clients musculoskeletal function,
    ROM, muscle strength, balance, and gait.
  • Ability and safety in using mobility aids
  • Observe clients emotional response to the
    disorder or disease.

48
Nursing Diagnosis
  • Established nursing diagnoses based on
  • data collected.
  • Planning and Implementation
  • Include clients and their families
  • Preventing Disorders of immobility
  • Providing comfortable position and proper
    alignment
  • Providing skin care
  • Providing adequate nutrition
  • Providing activity and exercise
  • Evaluation
  • Periodically evaluate outcome care with clients
    families and members of the healthcare team.

49
Common Musculoskeletal Disorders
  • Amputation
  • Chronic Back Pain
  • Temporomandibular Joint Disorders
  • Degenerative Disorders
  • Repetitive Strain Injuries
  • Inflammatory Disorders

50
Systemic Disorders with Musculoskeletal
Manifestations
  • Gout
  • Lupus Erythematosus
  • Scleroderma
  • Rickets and Osteomalacia
  • Traumatic Injuries
  • Sprains
  • Strains
  • Dislocations
  • Fractures

51
Hip/Fracture Hip Replacement
  • Hip Fractures
  • Common in older adults
  • Refers to proximal third of the femur which
    extends up to 5 cm below the lesser trochanter.
  • Intracapsular fracture - Fx occur within the the
    hip joint capsule. ( femoral neck)

52
Clinical Manifestation
  • External rotation.
  • Muscle spasm
  • Shortening of the affected extremity and
  • Severepain and tenderness in the region of the
    fracture site.
  • Note Displaced femoral neck fx causes serious
    disruption of blood supply to the femoral head
    which can result to avascular necrosis of the
    femoral head

53
Collaborative Care
  • Surgical repair preferred method of managing
    intracapsular and extracapsular hip fractures.
  • Permits early mobilization of the pt. and
    decrease risk of major complications.
  • Initial tx- immobility temporary with Bucks
    traction until physical condition stabilize.
  • Bucks traction relieves painful muscle spasm
  • Used for 24 to 48 hours maximum

54
Bucks Traction
55
Pre-operative Mgt.
  • Consider when planning tx chronic health
    problems.
  • Appropriate analgesics or muscle relaxant
  • Comfortable positioning unless contraindicated.
  • Properly adjusted traction.
  • Careful preoperative teaching can affect
    mobility.
  • Teaching done at the ER
  • Consider cognitive abilities.

56
Preoperative Mgt.
  • Teach - Method and frequency of exercising for
    the unaffected leg and both arms.
  • Encourage use of overhead trapeze bar and
    opposite side rails to assist in changing
    position.
  • Inform family of weight bearing status after
    surgery.

57
Post- operative ORIF
  • ORIF open reduction external fixation
  • Monitoring V/S
  • Monitoring I and O
  • Supervise respiratory activities Deep breathing
    exercises, couhing, use of spirometer.
  • Pain medication administration cautiously.
  • Observe for dressing and insicion for s/s
    bleeding and infection.

58
Early post operative
  • Assess for pt. extremity on
  • color
  • Temperature
  • Capillary refill
  • Distal pulses
  • Edema
  • Sensation
  • Motor function
  • Pain

59
Things to note for
  • Pain resulting from poor alignment of extremity
    can be reduced by keeping pillows between the
    knees
  • Sandbag and pillows are used to prevent external
    rotation.
  • With PT collaboration supervise active assistance
    exercises for the affected extremity.
  • Ambulation begins usually between first or second
    post-op day day

60
Complication to monitor
  • Non-union avascular necrosis
  • Dislocation
  • Degenerative arthritis
  • Hip Fx can be treated by insertion of femoral
    head prothesis.

61
Measures to prevent Dislocation
  • Do not force hip into greater than 90 degrees of
    flexion
  • Force hip into adduction
  • Force hip into internal rotation
  • Cross legs
  • Put on own shoes or stockings until 8 weeks after
    surgery without adaptive device ( use long
    handled shoe horn.

62
Measures to prevent Dislocation
  • Do
  • Use toilet elevator on toilet seat
  • Place chair inside shower or tub and remain
    seated while washing on good side or when supine
  • Keep hip neutral when sitting walking or lying
  • Notify surgeon if pain, deformity, or loss of
    function occurs.
  • Inform dentist of presence of prosthesis before
    dental work so prophylactic ATB can be given

63
Osteoporosis
  • Osteoporosis is a disease of bones that leads to
    an increased risk of fracture. In osteoporosis
    the bone mineral density (BMD) is reduced, bone
    microarchitecture is disrupted, and the amount
    and variety of proteins in bone is altered.
  • Osteoporosis is most common in women after
    menopause, when it is called postmenopausal
    osteoporosis, but may also develop in men, and
    may occur in anyone in the presence of particular
    hormonal disorders and other chronic diseases or
    as a result of medications, specifically
    glucocorticoids, when the disease is called
    steroid- or glucocorticoid-induced osteoporosis
    (SIOP or GIOP). Given its influence in the risk
    of fragility fracture, osteoporosis may
    significantly affect life expectancy and quality
    of life.

64
Osteoporosis
  • Osteoporosis can be prevented with lifestyle
    changes and sometimes medication
  • In people with osteoporosis, treatment may
    involve both. Lifestyle change includes exercise
    and preventing falls as well as reducing protein
    intake medication includes calcium, vitamin D,
    bisphosphonates and several others.
  • Fall-prevention advice includes exercise to tone
    deambulatory muscles, proprioception-improvement
    exercises equilibrium therapies may be included.
  • Exercise with its anabolic effect, may at the
    same time stop or reverse osteoporosis.
    Osteoporosis is a component of the frailty
    syndrome.

65
Pathogenesis
  • Imbalance between bone resorption and bone
    formation.
  • The three main mechanisms by which osteoporosis
    develops are an inadequate peak bone mass,
    excessive bone resorption and inadequate
    formation of new bone during remodeling. Hormonal
    factors strongly determine the rate of bone
    resorption lack of estrogen (e.g. as a result of
    menopause) increases bone resorption as well as
    decreasing the deposition of new bone that
    normally takes place in weight-bearing bones. The
    amount of estrogen needed to suppress this
    process is lower than that normally needed to
    stimulate the uterus and breast gland.

66
Sign and symptoms
  • Signs and symptoms
  • Osteoporosis itself has no specific symptoms its
    main consequence is the increased risk of bone
    fractures. Osteoporotic fractures are those that
    occur in situations where healthy people would
    not normally break a bone they are therefore
    regarded as fragility fractures. Typical
    fragility fractures occur in the vertebral
    column, rib, hip and wrist.

67
Risk factors
  • Advanced age (in both men and women) and female
    sex estrogen deficiency following menopause is
    correlated with a rapid reduction in bone mineral
    density.
  • Those with a family history of fracture or
    osteoporosis,
  • Excess alcohol
  • Vitamin D deficiency

68
Risk factors
  • Tobacco smoking
  • Malnutrition
  • Underweight/inactive - bone remodeling
  • Excess physical activity
  • Heavy metals - exposure to cadmium
  • Diseases and disorders ex. Cushing syndrome.
    Hyperparathyroidism and hypothyroidism.
  • Medications steroids, barbiturates, phenytoin,
    barbiturates.

69
Treatments
  • There are several medications used to treat
    osteoporosis, depending on gender. Medications
    themselves can be classified as antiresorptive or
    bone anabolic agents. Antiresorptive agents work
    primarily by reducing bone resorption, while bone
    anabolic agents build bone rather than inhibit
    resorption. Lifestyle changes are also an aspect
    of treatment.

70
Treatments
  • Antiresorptive agents Bisphosphonates
  • Fosamax) 10 mg a day or 70 mg once a week,
    risedronate(Actonel) 5 mg a day or 35 mg once a
    week and or ibandronate(Boniva) once a month.
  • Estrogen analogs
  • Estrogen replacement therapy remains a good
    treatment for prevention of osteoporosis but, at
    this time, is not recommended unless there are
    other indications for its use as well.
  • Raloxifene
  • Calcitonin

71
  • Bone anabolic agents
  • Teriparatide (Forteo, recombinant parathyroid
    hormone residue
  • Calcium salts come as water insoluble and soluble
    formulations.
  • Sodium fluoride

72
Prevention
  • Methods to prevent osteoporosis include changes
    of lifestyle..
  • Fall prevention can help prevent osteoporosis
    complications.
  • Nutrition- Proper nutrition includes a diet
    sufficient in calcium and vitamin D
  • Patients at risk for osteoporosis (e.g. steroid
    use) are generally treated with vitamin D and
    calcium supplements and often with
    bisphosphonates.
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