?????????? Rational Use of Drug ? ?

1
??????????Rational Use of Drug? ?

• ?????????????????
• ???????????????
• 2011?4???

2
?????????????????(2011??)
???????
?????
???????
????
????????
???????
??????????
?????????
3
?????????????????(2011??)
???? Prescription indicators
?????????? Rational Use of Drug
???????? Indicators of antimicrobial drug use
???????????? Antimicrobial drugs use indicator of
perioperative clean incision
4
(?)????(Prescription indicators)

• ??????????
• ??????????????????
• ????????????
• ??????????
• ???????????
• ????????????,???????????????
• ????????????
• ???????????????,?????,??????????????????,?????

5
?????

• ????????????,?????????????,???????????????????????
  ????????
• ????????????????????????
• ????????????,???600???????,???????????????20?????,
  ????30?????(??600???)?
• ???????????????,???????????????100??,??????????

6
????

• ???????????????
• ????????
• ?????????,????

7
(?)????(Prescription indicators)
1.???????????
??

• ????????????
• ?????????????????????????????
• ?????????????????.
• 1??????????????????
• ?????(??????????????)?

7
8
(?)????(Prescription indicators)
2.????????
??

• ????????????
• ?????????????????.
• 1???????????????????
• ?????(????????????????)?

8
9
(?)????(Prescription indicators)
3.????????????
??

• ????????,???????????
• ??????????
• ????????????????????,???????????,???????????????
  ????,???????????1??
• ??????????????????,???????,??????????????????
• ????????????????????????100?

9
10
?????????

• ??????????????,??????????
• ?????????????????????????????????????
• ?????????????????????????????????,??????

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(?)????(Prescription indicators)
4.????????????
??

• ????????,???????????
• ??????????
• ??????????????????????,???????????,?????????????
  ????????,????????????1??,?????
• ??????????????????,???????,???????????????????
• ????????????????????????100?

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12
????????????

• ??????????????????????,???????????????
• ???????

13
(?)????(Prescription indicators)
5.?????????????
??

• ???????????????????????????????????????????????
  ????
• ?????????????,?????
• ??????????
• ????????????????????????????????100?

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(?)????????(indicators of antimicrobial drug use)
1.???????????????
??

• ???????????????????????????
• ??????????,??????????,????,???????????????????
• ???????????,?????????????
• ??????????
• ???????????????????
• ??????,???????????????????????????????

14
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(?)????????(indicators of antimicrobial drug use)
2.??????????????
??

• ??????????????????????
• ??????????,??????????,????,???????????????????
• ???????????,?????????????
• ?????????????????(??????)?
• ??????,??????????????????????????????

15
16
(?)????????(indicators of antimicrobial drug use)
3.??????????????
??

• ?????????????????
• ?????????????????,?????????????????(??????),????
  1??????????
• ???(????????????????)??,?????????????????

16
17
(?)????????(indicators of antimicrobial drug use)
4. ????????
??

• ???????????100??????????DDD??
• DDD???WHO????????????????(defined daily doses
  , DDD),????????????DDD?????
• ???????DDD???????????DDD?(?/DDD?)?
• ???????(??DDD?)??????DDD????
• ??????????????????????????????????????

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18

• ????????(DDD)
• DDD???????????????????(??)????100?1000??????????
  ??DDD?
• DDD?????????????????????

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DDD
????????
(defined daily doses, DDD)
The DDD is the assumed average maintenance dose
per day for a drug used its main indication in
adults
DDD???????????????,????????????????????????
??????????????DDD???DDD,????????????????DDD???????
????????????????????????????DDD?????????????,?????
?????????????????DDD??
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DDD
Defined Daily Doses
DDD
?
???? 24???
???? 1?
???? 4?


??? 1DDD
???? 1DDD
???? 1 DDD


3DDD
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(?)????????(indicators of antimicrobial drug use)
5. ???????????????
??

• ????????????????????
• ?????????????????????????100?

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(?)????????(indicators of antimicrobial drug use)
6. ??????????????????????
??

• ????????????????????????????
• ???????????????(??DDD?)??????????(??DDD?)?100?

22
23
(?)????????(indicators of antimicrobial drug use)
7. ?????????????????
??

• ???????????,??????????????
• ?????????????????????
• ???????????????????????????????????100?

23
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(?)????????????

• ???????????????????????????????,???????????????,??
  ???????????????????????,??????ADR?????????????????

25
(?)????????????
(antimicrobial drug use indicator of
perioperative clean incision)
1. ??????????????
??

• ?????????????????
• ????????????????????????????
• ???????????????????

25
26
(?)????????????
(antimicrobial drug use indicator of
perioperative clean incision)
2.?????????????????
??

• ?????????????????
• ??????????????????????????????????????
• ??????????????????????????????

26
27
(?)????????????
(antimicrobial drug use indicator of
perioperative clean incision)
3. ???????,??0.5-2.0????????
??

• ???????????????????????
• ?????????????????????,??????????0.5-2.0??????????
  ?,?????
• ??????????

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(?)????????????
(antimicrobial drug use indicator of
perioperative clean incision)
4. ???????0.5-2.0????????
????????0.5-2.0????????
??
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(?)????????????
(antimicrobial drug use indicator of
perioperative clean incision)
4. ???????0.5-2.0????????
?????????0.5-2.0????????
??
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30
(?)????????????
(antimicrobial drug use indicator of
perioperative clean incision)
4. ???????0.5-2.0????????
?????????0.5-2.0????????
??
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