Title:
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Grace?? Steg et al Circulation 2004
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Plt0.05 Plt0.0001 P0.013 ,???????
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Hall SA, et al. J Am Coll Cardiol
1995351154-1161
13(No Transcript)
14????????ß?????CAPRICORN (n1959)? MERIT-HF
(n1926)
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P?
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151/116 122/74
CAPRICORN
23
p0.03
?????1 ?2 (?1)
MERIT-HF
40
p0.0004
??????? ?1
??????/?????
367/340 326/258
8
CAPRICORN
ns
?????1 ?2 (?1)
p0.002
MERIT-HF
22
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0.0
1.0
?????95 CI
The CAPRICORN Investigators. Lancet
20013571385-1390. Janosi A et al. In
preparation.
15ß????? ???????????
SOLVD-T (1991) ??????21
MERIT (1999) ?????? 34
CHARM-Added (2003) (? ???????) ??????30
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????????????????????? 2002, 30(1)7-23
21(No Transcript)
22 23ß?????????????
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24ß??????????
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25ß??????????????
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283?ß-?????????
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29 30??????????ß??????
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Gunderson 1884 ???? 138 (15.5) 92 (10.3) 14 (30.5) 6 (11.3)
BHAT 3837 ???? 155 (9.2) 116 (6.9) 33 (14.4) 22 (9.3)
Kjekshus 1670 ???? 103 (12.8) 42 (6.5) 33 (23.4) 13 (10.2)
?? 7391 396 (11.7) 250 (7.8) 80 (19.2) 41 (9.9)
?-???????? ?-???????? ?-???????? 33 33 48 48
31????????????ß??????
1.0 0.8 0.6 0.4 0.2 0.0
Proportion Surviving
Gottlieb SS et al N Eng J Med 1998339489
32??????????ß??????
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????? 90? 65-74 ???? 45(p0.032)
??????? ??61? 65-74 ???? 19(p0.022)
?-?????? ??25? 60-69 ???? 33(plt0.031)
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ACC/AHA????????????????
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ACC/AHA????????????????
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