??????(stereochemistry)

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??????(stereochemistry)

• ?.????(optical isomerism)

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(?)??????????

• 1.?????
• ???????,?????????????????

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(No Transcript)
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• ?????(?????),????????????????
• ????????????????,???????????

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(No Transcript)
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2. ???
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3.???

• ????????????????????????????,???????????????

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????

• ???????????????????,a,??(-),??()?

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(No Transcript)
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?????
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(?)?????????

• 1.??(?)???????????????????????,???????????

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• 2.??(?)???(???C chiral carbon atoms)????????

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3.?????

• ??????????????????(???),?????,??????

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?????

• ?????????????? ?

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????

• Racemic mixture
• ??????????????,????0,???????

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4.Fischer???(??C)
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????

• ??????C??????????????,?????????????
• ??????????,????C?????

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?????????????180?
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??????????
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?????????90??270?
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(?)???????1. D? L??
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(No Transcript)
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3.R?S??

• ?????
• 4????????(????)??,????????????????????3???????????
  ,????????,?R??,??,??S?

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(No Transcript)
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? Fischer???
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• 4????????(????)??,?????????,???
  3???????????,????????,?R??,??,??S?

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R
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• 4????????(????)??,?????????,? 3???????????,???????
  ?,?S ??,??,??R ?

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R
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(?)????????????

• 1.??????????????
• ???
• ????
• ???

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(No Transcript)
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2.??????????????(????)
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N???C,?????,2n
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(?)????????????
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1.???
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(No Transcript)
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2.????
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(?)?????

• 1.????
• ?????????????????????,???????????????????

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• ????????
• ??????????????????,???????????????????,??????????
  ??

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2.????

• ?????????????,?????????,???????????????????

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3.????

• (-)????????????()??1215??
• (-)?????????()??100??

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(-)???
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(-)????
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(?)???????

• 1.?????
• ?????????????????????

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• ????(??)?????????
• ????,?????????
• ???????????????

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2.???????

• ????????(????)???????
• 3.?????

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?.????

• (?)???????????

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1.???
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2.???
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(?)????

• ??C-C???????????????????????????????

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1.??

• ???,???,??12.5 KJ/mol
• 2.?? ??13.8 KJ/mol

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3.???

• (????)???, (????)???

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4.???

• ?????
• ???????

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(No Transcript)
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?.?????

• 1.????
• ?????????????????

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2.????

• ????(?????)
• ????