???PET???????? ????1

1
???PET???????? ????1

• ?????
• 1.????? ????????????
• 2.MovilePET ????PET-
• ??????????(????,???????)
• 3. ????????(????????...)
• 4.????Image Guided Particle Therapy(IGPT)
• 5.4D PET MotionFreeze
• 6.???PET ??
• 7.??????????PET?????????
• XePET/TOM5

??????PET/CT???!
2
PET????1
?1???3????????PET(SET-2400W, ????)
1????? 3.71010 ????
3
PET????2 ??G
?????????????????PET???????? ?????????????????????
?????????? ???????????????????????????????????????
??????????????PET???1mm???????????????????????????
?????????????????????? ????????????????????1?????
?????? ???????????????????????????????? ??????????
?????????????????????? ???????????????????????????
???????? ??????????????????????????????? ?????????
????????
1.4mm??????????(LYSO)
???
?????PET??"jPET-RD"???
DOI3?????
??????PET????5????????
4
PET????3 ??G
?2??? ??G
5
PET????4 ??G
6
PET????5 ??G
???3mm?????100kcps/MBq
?????4?DOI??????? ????????????????? ??????????????
??????????????????????2mm(????)?6mm(????)??????? ?
???????????1mm?1.5mm??? ????????????DOI???6??8????
???? ????????????8?DOI?????? ???1mm???????????????
????? ??????????????????????? ????????????? ??????
?????????DOI??????????????
7
PET4?????-?????????
????PET????? ??? PET?4???????????????????????????
?????? 1)?????/????????? 2)????????? ???????????
????????????????????????? 3)?????? ?????????????
??????????????????? ??????????????????????????????
??????? ?????????? ?????????????? ????????????????
?????????? 4)?????? ??????PET/CT?????????????????
?????????? CT?????????????????????????????????
8
???PET?? ???3
????????????????? PET ???? PET/CT?????????????????
?? ?????3??????? 1) GE 2) Siemens 3)
Philips (????????????????????) ???????????????????
????????????? ??????????????????????????????? ????
????? 1) ????? ST ???? Discovery ST Elite 2)
???????PET/CT TruePoint PET/CT 3) ???? TF ????
Gemini TF system ????????? 1)
TOF(?????)??????????4??PET 2)
???PET????????????????? 3) ???? TF
?????????????????? ??(?????)???????????
9
August 14, 2006Time of Flight ? Next-Generation
PET Takes Flight?By Dan Harvey?Radiology
Today?Vol. 7 No. 16 P. 20
http//www.radiologytoday.net/archive/rt08142006p2
0.shtml
WhilePET use is certainly growing, the technology
itself is also evolving. The 2006 Society of
Nuclear Medicine (SNM) meeting highlighted
developments in PET technology. One of the more
interesting stories to emerge from the meeting
involved a look to the past as an older concept
staged a reemergence. Philips Medical Systems
introduced its Gemini TF system, utilizing
time-of-flight (TOF) technology. GE Healthcare,
with its Discovery ST Elite, gave attendees an
introductory look at a redesigned PET/CT system
that can perform respiratory gated studies.
Siemens, with its new TruePoint PET/CT platform,
showcased a system that provides an extended
field of view. The new products represent a
natural, ongoing evolution of these companies?
PET/CT technology.
10
Big3 GE
PET-CT???????Elite Technology ??????? VUE
Point S/N?35Up1 1(???) ?????? Dimension
Console 2????4?????????PET 4Dx CT????????? Rad
Rx Elite BGO Detector ???????BGO ?????LightSpeed
CT ????????? ????????????????????????? ????? Ad
enocarcinoma in the stomach ?????????? ?
???????? ????????
GE Healthecaere
Respiratory gate systems
http//www.gehealthcare.co.jp/rad/nm/dis_ste_index
.html
11
Big3 Siemens
Siemens TruPoint
12
Big3 Philips
http//www.medical.philips.com/main/products/ pet/
products/gemini/gemini_tf_commercial.asp
13
PET ??????????
PET ??????????????????? ??????????????????????? ??
????????????????????????? ????????????????????? ??
?????????????? ????????????? ?????????????????? ??
??????????????????????????????????? ??1)?????????
?????? ????? ???????(MeV) ????(mm)
????(mm) 11C 0.961
3.9 1.1 13N
1.190 5.1
1.5 15O 1.723
8.0 2.5
16F 0.635
2.4 0.6 ??????????????????????
?????????? ???????????????2?????? FDG
????????????????????????????? ??2)???????????????
???????????? ?????????????????????????????????? ??
??????0.5???????180???????????????? ??????????????
??????? ??????PET???????????????????PET???? ???PET
???????????????????????? ????????
14
http//www-atm.jst.go.jp8080/pict/08/08020104/08.
gif
15
???????
PET???????????????? ????? Noise Equivalent Count
Rate (NECR) TRUES rate2 /(TRUES rate RANDOMS
rate SCATTER rate) http//egems.gehealthcare.co
m/geCommunity/europe/nmpet/pet_education/prompt.ht
ml ?????????2????????3????????? ?????????????????
????????????? ????????????????????????????????????
???? ??????????????????????????????
???????????? ???????????(activity)???? NECR ????
4 micro Ci/cc ??????????????? ????????????????????
??? ????????????????????????
16
NECR
NECR?PET????????????? ????????????????????? ??????
??????????????????? ???? ?????????????????????????
?? ??????????????
???????????NECR ? NECRgamma-camera 1
NECRhexagonal NaI(Tl) 17 NECRring BGO
50. ?????????????????! ?????????
17
NECR plot
18
FDG ?range????????????????
PET???????????????????????? ???????????????? ?????
????? ???????????????????????????? ???????????????
?? ??, ?? ?? ??? ? ??? ???????????? ??????????
????????????? ????????????????????????????
19
????FDG???????????
?????????????FDG????????????????????? ????????????
?????? 18FDG?????????????????????????(???)???? ?
????????????? hexokinase ????? ????? 18FDG-6
phosphate???????????????????????
20
???PET??????????
CT ?PET ??????????????????? ??????2???????????????
???? ??????????????????????? ?????????????????????
????? ????????????????? ????????????????????????
????????????????????????????? ?????????????????? ?
?PET??????????????????? http//www.kohnan-sendai.o
r.jp/nougeka/Epilepsy_Surgery/pet.html ????? ???
????FDG??????????????????????? ???????????????????
???? ????1-3mCi(????????40-180 MBq)????1
mCi????????? ????????????????????????? (??????????
????)??????1/5??? ????????????????????????????? ??
?????1983???????????????????? ???????????????????
?????????? ?????????????????????????????
21
LXePET?????????????(TPC?)????????????