HCS - PowerPoint PPT Presentation

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HCS

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HCS Objective To determine if measurement of postprandial TG level improves risk prediction of CV events over traditional risk markers in stable patients with CVD – PowerPoint PPT presentation

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Title: HCS


1
HCS
  • Objective
  • To determine if measurement of postprandial TG
    level improves risk prediction of CV events over
    traditional risk markers in stable patients with
    CVD
  • Study Design
  • Prospective, observational, cohort (18-month time
    frame)
  • 514 consecutive patients with angiographically
    confirmed, clinically stable CAD
  • Primary Outcome
  • Composite of CV death and CV hospitalization
    (including hospitalization for ACS, unplanned
    coronary angiography, HF, ischemic stroke or TIA,
    cardiac arrhythmia requiring resuscitation, and
    unplanned cardiac device implantation)

2
HCS
Key Findings
3
HCS
  • Summary
  • Postprandial TG did not predict CV outcomes in
    the total cohort of patients with CAD on statin
    treatment
  • In patients with CAD and IGT/diabetes, fasting
    and postprandial TG were elevated but did not
    independently predict CV outcomes
  • In patients with CAD and normal glucose
    metabolism, both fasting and postprandial TG were
    independent markers for CV outcomes
  • Conclusion
  • Fasting triglycerides and postprandial
    triglycerides correlate with CV events in
    patients with CAD and normal glucose tolerance
    but do not independently predict CV outcomes in
    patients with impaired glucose metabolism
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