NIH eRA KM

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NIH eRA KM eReceipts Integration
Briefing Notes Bethesda, MD February 2006 David
RR Webber webberd_at_od.nih.gov
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Executive Perspectives

• eRA and KM potential
• KM Technology Overview
• eReceipts Grants Applications today
• eReceipts eXchange toolkit
• Community of Practice
• Opportunity Brainstorming

3
How can KM help the Grants Process?

• Goals
• Making best science the overarching award
  criteria
• Enhancing referee selection
• Pattern matching with research community
  -Medline, SwissProt

• Building PI KBase
• Focusing grants on optimum topics
• Grant opportunity discovery / awards KBase
• Providing KB tools to submitters

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Mechanisms Timeline
SBIR/STTR (April 1)
Mechanism Abbreviation Key C06/U06 Research
Facilities Construction Grants D71/U2R
International Training Cooperative Agreement/
Phase 2 of FIC mechanism D71 R01
Research Project Grant Program R03
Small Grant Programs R10/U10 Cooperative
Clinical Research Grants R13/U13 Support for
Conferences Scientific Meetings R15
Academic Research Enhancement Awards
(AREA) R18/U18 Research Demonstration and
Dissemination Projects
R21/R33 Exploratory/Development
Research R24/U24 Resource Related Research
Projects R25 Education Projects R34
Clinical Trial Planning Grant Program R36
Research Dissertation Grant Program SBIR
Small Business Innovation Research STTR
Small Business Technology Transfer S06,S10,S11
Biomedical Research S21,22 Health Disparities
Endowment Grants U Cooperative
Agreement Awards X02 Preapplication
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KM Technology

• Overview

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Insights into Knowledge Challenges

• How do we provide vital input to form a core
  knowledge base from electronic Grants application
  submissions?

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Challenges for PDF Processing
WE ARE HERE!
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Supporting Knowledge Management

• Shared Community Registry tool is essential
  reference point
• Portal and ad hoc documents are not enough
  needs to formalize science and provide CFP
  semantic alignment tools

• Coherent navigation and search / discovery tools
• Research Partner Collaboration / teaming /
  exchange support

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Registry of Semantic Association Networks

• Katy Börner. (2006) Semantic Association
  Networks Using Semantic Web Technology to
  Improve Scholarly Knowledge and Expertise
  Management. In Vladimir Geroimenko Chaomei Chen
  (eds.) Visualizing the Semantic Web, Springer
  Verlag, 2nd Edition, chapter 11, pp. 183-198.

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Creating Domain Terminology Registry
Co-word space of the top 50 highly frequent and
bursty words used in the top 10 most highly
cited PNAS publications in 1982-2001. (Mane
Börner, 2004)
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Patterning Grant Awards - NIH
Funding Patterns of the National Institutes of
Health (NIH)
GI
12
Patterning Grant Awards - NSF
Funding Patterns of the National Science
Foundation (NSF)
GI
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Knowledge Optimization in Research Funding
Over the next 5 years I believe technology will
take a leading role is science advancement -
Miles Radford, Wellcome Trust Software will be
able to-

• identify areas of research that should be pursued
  (hypothesis generator)
• provide relevant material for researchers to
  read, Provide meta analysis of research
  activity/proving vastly improved management
  information
• generate new knowledge directly

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eReceipts Grants Applications today

• Components

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The Technology Components

• PDF based document submission to text content of
  proposals
• Can be enhanced with XML meta tags and content
  labelling and context if PDF templates / semantic
  tools are used to aid submitters.
• XML of submitters proposal including demographic
  information and budget information
• Can be scanned and information extracted
• PI profiles currently only administrative
  information but semantics or links concerning
  their research
• Single submission point through Grants.gov who
  control the base forms and layout / content
  schemas

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eReceipts eXchange toolkit

• Available Technologies

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Components and Functionality

• Hermes client messaging solution for secure
  G2G and B2G information exchanges
• Registry system for classification and semantic
  information storage
• Prof Dodac research on semantic information
  storage http//www.inderscience.com/search/index.
  php?actionrecordrec_id8767prevQueryps10mo
  r
• Transaction Handling Services Agent
• Provides dynamic rule driven XML content handling
• eXchange integration server
• supports multiple methods for information
  transfers

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Toolkit - Open eXchange Concepts
Submissions / Transfers
Dispatch Queue
Delivery Queue
Grants.gov
Pluggable Status Tracking
Neutral Data Handling Layer
1
ebXML
eXchange Hub
Data Persistence Agent
Pluggable Interfacing
HL7
2
4
3
Other
Script
Content Validation Agent
PDF Handling Services
Script
Dispatch Agent
Script
Script
Registry Services
Interfacing
Script
Script
Script
KBase Handling
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Semantic Hierarchies
Partner Profiles
Research Cues / Triggers
Knowledge Tools
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PI Profiles
KBase Services
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Community of Practice

• Other Perspectives

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GSA - creating Grants CoP

• GSA is building as part of the SICoP work a web
  site and community initiative (http//www.gsa.gov/
  collaborate )
• State and Federal level participation
• Goal library of shared experience and
  components
• Example Michigan system for State grants -
  .NET based and rule configurable to any states
  needs.

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Grants - Michigan State - eGrAMS
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Completely Rules Based System
Narrative section
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Opportunity Brainstorming

• NIH eRA Perspectives

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NIH - Knowledge Metrics and Challenges

• From the current Grant Applications and database
  structures how will we bring in knowledge based
  searches and medical community integration?
• Currently data is configured to support
  traditional internal business application needs
• How do we create long term conceptual components
  that will grow as knowledge representation
  matures?
• How do we integrate to external knowledge
  sources?
• Providing direct submission support to
  researchers?
• Integration into caBIG conceptual platform and
  Grid?
• Provide support for Web 2 aware solutions?

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Opportunity Goals

• Create a diverse external service community
  interfacing into NIH processes
• Create extended support for grant applicants that
  reduce the burden on submitters
• Develop a pluggable exchange system that goes
  beyond R424/398 Grants
• Create a rule driven approach that is transparent
  and highly adaptable
• Leverage available messaging solutions and
  community tools architecture
• Participate in Federal Community of Practice to
  create long term benefits / ROI

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Beyond Grants Applications?

• The ability to interface quickly and easily to
  external parties with limited resources is not
  just a grants applications need
• Secure reliable verifiable common communications
  infrastructure based on open public
  specifications
• Other potential applicable areas
• HHS - Cancer Research Centers
• CDC Emergency Alerting systems
• Navy Medical Services coordination
• FEMA Emergency supply chain delivery
• DHS Intra-agency information sharing
• EPA External regulatory reporting