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Early cancer detection.

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Title: Early cancer detection.


1
Early cancer detection.
  • Dr. Mounir M. Fawzy El-Hao
  • Prof. of Ob/Gyn
  • Ain Shams University
  • Cairo - Egypt

2
Cancers of the female genital tract
  •  
  • ????? ?????? ?? ????? ??????.
  • ???? ??? ?????? ?? ??????? ??? ?????? ?? ??????
    ????????.
  • ???? ?????? 5 ????? ??? ???? ?????
  •  
  • Endometrial Cancer
  • Ovarian Cancer
  • Cervical Cancer

3
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4
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5
Cancers of the female genital tract.
  • Ovarian
  • Uterus
  • Vagina
  • Cervix
  • Hydatidiform Mole/Gestational Trophoblastic
    Disease
  • Breast

6
Transformation zone
7
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9
Selection of tools (spatula slides)
10
Selection of tools (spatula slides)
11
Selection of tools (spatula slides)
  • Proper sampling of squamous, TZ and endocervix
  • Brush may be important in postmenoausal women
  • Slides that can be written upon

12
THE COLPOSCOPE.
13
  • Cancer cervix
  • ?? ?? ??? ????? ?? ??? ????? ??? ??????? ??? ???
    ??? ????? ????? ??? ?????.
  • Cancer cervix
  • ?? ?? ??? ????? ?? ??? ????? ??? ??????? ??? ???
    ??? ????? ????? ??? ?????.
  • Cancer cervix
  • ??? ????? ?? ????? ?????? ?? ????? ??? ????? ????
    ??????.

14
  • Cancer cervix
  • ?? ?? ??? ????? ?? ??? ????? ??? ??????? ??? ???
    ??? ????? ????? ??? ?????.

15
.
  • Cancer cervix
  • ??? ????? ????? ???????? ??????? ?????? ???
    ?????
  • ???????? ??????? ???? ???? ??????? ??????
    ???????.
  • ??? ???????.

16
Acetowhite epithelium
  • Maximum whiteness reached
  • Rapidity of development of maximum whiteness
  • Length of retention of whiteness

17
Mosaic and punctation
18
Features suggestive of invasion
19
HPV
.
  • ???? ?? 100 ??? ??????? ????.
  • ??? ????? ?????? ?????? ????? 16, 18, 31, 33, 45.

20
HPV
  • ????? ??????? ?????? ????? ?????? (???? ?? ??
    ????).


21
. High risk. 16,18,31,33,39Low risk 6
11 
HPV
22
Cancer cervix
  • ???? ????? ??? ????? ???? ???? ?????? ????? ???
    ????? ???????? (???????? ???????) ?? ??????? ????
    ???? ?????.

23
Cancer cervix
  • .
  • ??????? ???????? ????? ??? ????? ?? ??? ???????
    ??? ????? ??????? ???? ???? ????? ?? ???? ??? ???
    ?????.

24
Cancer cervix
  •  
  • ??????? ?? ???? ???? (????? ??? ?????).
  •  

25
Cancer cervix
  • ??? ??? ????? ?? ??? ??????? ????? ??? ?????
    ????? ?? ???????.
  •  

26
Cancer cervix
  • ????? ?? ?????? ??????? ?? ??? ???? ????? ??? ??
    ????? ??? ????? ?????? ???? ????? ?????? ???? ??
    ??????.
  • ????? ??????? ??????
  • .  
  •  

27
   ????? ????? ???????? ?????? ??? ????? ?????
?? ?????? ??????? ??????. 
Cervical Cancer
28
  • Cancer cervix
  • ????? ??????? ??????? ?????? ??? ?????
  • ??? ??? ????? ????????? ?? ????????.
  • ??????? ?????.
  • ??? ??? ?????? ????? (?? ???? ??????).
  • ???? ??? ??????.

29
Cancer cervix?? ???? ??? ????? ??? ????????
???? ???? ??????? ???????? ?????? ??????. 
30
??????? ?? ??????? ???? ???? ????? (??? ???
HPV 6, 11, 16, 18 ) ??? (Gardasil) (???? 16, 18)
??? (Cervarix). 
31
Cancer cervix
  •  
  •  
  • Pap test or Pap smear
  • ?? ????? ?????? ??????? ?????? ?? ??? ???????.
  •  

32
  • Colposcopy
  • ?????? ?????? ???? ????? ?? ????? ???? ????? ???
    ?????? ?? ???? ?????? ???????? ???? ?????.
  •  

33
HPV
  • ??? ???????? ??????? ????? ???? ???? ??? ?????
    ???? ??????? ?????? HPV.
  • ???????? ??????? ???????.
  • ???????? ??????? ?? ??? ?????.
  • ???????? ?? ??? ?? ?????? ??????.
  • ????? ?? ??? ??? ????? (Uncircumcised).

34
HPV
  •  
  • ???? ?????? ?? ???? ????? ???? ?? ???? ???? ?????
    ????? ????? ????? ?? ???? ????? ???? ??? ???? ??
    ???? ??.
  •  

35
HPV
  •  
  • ??? ???? ????? ????? ????? ?? ???? ??? ????
    ?????.
  • ???? ??????? ?????? ?? ??? ????? ???? ?? ????
    ???? ?? ????? ????? ??? ?????.
  •  
  •  

36
HPV
  • ??? ???? ?? ????? ?????? ?? ???? ?????? (HPV)
    ????? ???? ?? ??? ?? ?? ???? ???????? ????? ??
    ????? ??? ?????.
  •  
  •  

37
HPV
  • ???? ????? ????? ????? ???? ??????? ????? ?????
    ????? ??? ?????? ???? ???????.
  •  

38
HPV
  • ??? ??????? ???????? ??? ???? ????? ??? ?????.
  • ???????
  • HIV
  • Chlamydia
  • ?????? (??? ???????? ????????).
  • ????? ?????
  • ???? ??? ????? ?????? ?????.
  • ????? ??????? ???????.
  •  

39
HPV
  •  
  • Cervical biopsies
  • ???? ?? ??? ????? ?? ???? ???? ?????? ??? ??????.
    ???? ?? ??????? ??????? ???? ?????.
  •  
  •  

40
HPV
  • Cone biopsy
  • ???? ??????? ???? ????? ?? ???? ?? ?????? ???????
    ???? ??? ????? ??????? ?? ???? ????? ??? ??????
    ?????? ??????.
  •  
  •  

41
HPV
  •  
  • ??? ???? ???? ?? HPV
  • ???? ?? ??????? ?? ???? ?????
  • ?????? ????? ??? ??????? ??????? ??? ?????
    ???????? ??????? (???????).
  •  

42
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44
Ascitis.
45
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46
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47
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48
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49
Thank
  • You
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