Title: Evasion of Immunity I
1?????
Medical Helminthology
2????
- ? ?????? Introduction to Helminth
- ? ???? Introduction to Nematode
- ? ?????(??) Ascaris lumbricoides
- ? ??????(??) Trichuris trichiura
- ? ?????? (??) Enterobius vermicularis
3????
Medical Helminth
4(No Transcript)
5- ??????
- ???????????
- ??????
- ??????
- ???????
- ?????
- ????
6???
Class Nematoda
7(No Transcript)
8??
9?? ?????????,????,????,?????????????,????1m??(??
?????),????1cm(????)? ????????? ????????????,???
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10Eggs of Nematodes
11?????(??)
Ascaris lumbricoides
???????,?????,???????,???????????? ?????????????,?
??????????????? ??13????? ????????????
12????????????????????????????????,?????????
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???????,???,????????,????,????,??,????,???????,??
???,??????????,??????
13????
Morphology
141.??
Morphology of adult
- ????,????????????????
- ????????,????
15- ?20-35cm,????
- ?15-31cm,????, ???????1?
162.??
Morphology of egg
- (1)???
- ????
- 6545µm
- ???
- ????,?????????????
- ????????
17(2)????
- ????9040µm??????,????????????????????????????
18?????
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????
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19?????
Life Cycle
20 ?? ?? ????
????? ? ??? ? ?????
? ??????? ??2W ??
???????????60-75 d,??1???
21- ??????,?????????,??, ??????????
- ???2-3?????????
- ????,????????????7-10???????????????
22?????
- ??????
- ????????
- ??????
- ????? ?????,2 - 2.5??
- ?????1?
- ?????
23????
1.??
- ???????????,?????????,?????,???????????????????
- ????????,???????????
24????
??????????????,???????????,????????????????
??????????? ???????????????,???????????????
252.??
- (1)????????????
- ??????,?????????????????????????,?????
- ????????
- ???,???????
- ???
26(2)?????????
?????????????????????????,???????????????,???IgE??
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27(3)???
?????? ???? ???? ????
28(No Transcript)
29(No Transcript)
30Penetrating through the intestine
Blocked in the intestine
31 ??????
??,?,12??1997?3??????????????????????,????,???????
?????????,??????????????????????,?12??????????????
???4???????????,???????????????
32?? ???17??????,???????200???
???9???,?????,?????????????908???
??11?????1806?,?4KG
33??????
Diagnosis
????
?????(??) ???????
34??????
Epidemiology
1???
?????,????????????5.1????? ??????,??????? ???????
?????????????
352?????
- ????,??????
- ?????
- ?????????
- ??????
36??????
? ????????,????? ? ????????,????,
???? ? ??????,?????? ? ??????,????????
379?25?,3????????????????????3?5????????????????????
??,???????????????
?????????10?10?????????,?????????????,??????????
38??????????????????????????????
3911?1?,??????????????,???????????????????????7?????
??????2???????????1?????????????????
??????????????????,??????????????????????????????
????????????????????????
4011?3?,??????????????????,??16????????16???????????
?,????502??????3.2?????????????,?4????????,9?????
????,??3???????????????165????????????,8??????????
?
41??
1 ??????????????
2 ??????????????????
42??????(??)
Trichuris trichiura
????,?????????????????????,?????(trichuriasis)?
431.??
????
????,?3/5????,?2/5??? ?35-50mm,??????? ?30-35mm,??
????????
442???
- ???,???,5222 µm,???,????,????1????,????????
45?????
- ???????,?????????????????? ??,?????,?????
- ?????,?3?,????????????
- ????,???????,????,10???,????,?????,??????
- ???????,1-3???????3-5??
46(No Transcript)
47??????????
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???? ?? ??
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???? 3W 3W
???? ????? ?????
???? ?? ??
???? ????? ?
?????? 6075? 13?
???? 1? 35?
48????
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- ? ????
- ? ?????
- ? ??????????????????????????????????,30?
49???????
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50??????
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51???????
- ??????????????,????
- ????????????????
- ?????10??,???4000??
- ??????????????????????????????
- ??????????
52??????
Enterobius vermicularis
????(pinworm),??????(enterobiasis),???????,???????
??,?????????????????????
53????
?? ???1cm
??
??
54?????
55(No Transcript)
56- ????
- ??4?,??,??????20??,????????,?????????????1
997?6?17????????????1.5,????,??????????,????????
??,??????????????1.5????????????????????????,?????
?????,????7??????????10.5 mm 2?,11mm 4?,4.3 mm
1?????????????????,??????,??????????,???????,?????
??????????????????????
57- ?????
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- ????--??????????
- ???????
- ??????(?????)
- ??????
58??????
1????????????????? 2?????
?????????? ?????
59??????
Enterobius vermicularis
????(pinworm),??????(enterobiasis),???????,???????
??,?????????????????????
60????
?? ???1cm
??
??
61?????
62(No Transcript)
63- ????
- ??4?,??,??????20??,????????,?????????????1
997?6?17????????????1.5,????,??????????,????????
??,??????????????1.5????????????????????????,?????
?????,????7??????????10.5 mm 2?,11mm 4?,4.3 mm
1?????????????????,??????,??????????,???????,?????
??????????????????????
64- ?????
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- ????--??????????
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65??????
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