Evasion of Immunity I - PowerPoint PPT Presentation

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Evasion of Immunity I

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Title: Evasion of Immunity I Author: Staff and Students of UWA Last modified by: zz Created Date: 11/5/2002 2:38:50 PM Document presentation format – PowerPoint PPT presentation

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Title: Evasion of Immunity I


1
?????
Medical Helminthology
2
????
  • ? ?????? Introduction to Helminth
  • ? ???? Introduction to Nematode
  • ? ?????(??) Ascaris lumbricoides
  • ? ??????(??) Trichuris trichiura
  • ? ?????? (??) Enterobius vermicularis

3
????
Medical Helminth
4
(No Transcript)
5
  • ??????
  • ???????????
  • ??????
  • ??????
  • ???????
  • ?????
  • ????

6
???
Class Nematoda
7
(No Transcript)
8
??
9
?? ?????????,????,????,?????????????,????1m??(??
?????),????1cm(????)? ????????? ????????????,???
???,???????,????????????????(???)?
10
Eggs of Nematodes
11
?????(??)
Ascaris lumbricoides
???????,?????,???????,???????????? ?????????????,?
??????????????? ??13????? ????????????
12
????????????????????????????????,?????????
???,????,??,???,??????????,????,??,????,????,????
???????,???,????????,????,????,??,????,???????,??
???,??????????,??????
13
????
Morphology
14
1.??
Morphology of adult
  • ????,????????????????
  • ????????,????

15
  • ?20-35cm,????
  • ?15-31cm,????, ???????1?

16
2.??
Morphology of egg
  • (1)???
  • ????
  • 6545µm
  • ???
  • ????,?????????????
  • ????????

17
(2)????
  • ????9040µm??????,????????????????????????????

18
?????
???
????
????
?????
19
?????
Life Cycle
20
?? ?? ????
????? ? ??? ? ?????
? ??????? ??2W ??
???????????60-75 d,??1???
21
  • ??????,?????????,??, ??????????
  • ???2-3?????????
  • ????,????????????7-10???????????????

22
?????
  • ??????
  • ????????
  • ??????
  • ????? ?????,2 - 2.5??
  • ?????1?
  • ?????

23
????
1.??
  • ???????????,?????????,?????,???????????????????
  • ????????,???????????

24
????
??????????????,???????????,????????????????
??????????? ???????????????,???????????????
25
2.??
  • (1)????????????
  • ??????,?????????????????????????,?????
  • ????????
  • ???,???????
  • ???

26
(2)?????????
?????????????????????????,???????????????,???IgE??
????????
27
(3)???
?????? ???? ???? ????
28
(No Transcript)
29
(No Transcript)
30
Penetrating through the intestine
Blocked in the intestine
31
??????
??,?,12??1997?3??????????????????????,????,???????
?????????,??????????????????????,?12??????????????
???4???????????,???????????????
32
?? ???17??????,???????200???
???9???,?????,?????????????908???
??11?????1806?,?4KG
33
??????
Diagnosis
????
?????(??) ???????
34
??????
Epidemiology
1???
?????,????????????5.1????? ??????,??????? ???????
?????????????
35
2?????
  • ????,??????
  • ?????
  • ?????????
  • ??????

36
??????
? ????????,????? ? ????????,????,
???? ? ??????,?????? ? ??????,????????
37
  • 2005???????????

9?25?,3????????????????????3?5????????????????????
??,???????????????
?????????10?10?????????,?????????????,??????????
38
??????????????????????????????
39
11?1?,??????????????,???????????????????????7?????
??????2???????????1?????????????????
??????????????????,??????????????????????????????
????????????????????????
40
11?3?,??????????????????,??16????????16???????????
?,????502??????3.2?????????????,?4????????,9?????
????,??3???????????????165????????????,8??????????
?
41
??
1 ??????????????
2 ??????????????????
42
??????(??)
Trichuris trichiura
????,?????????????????????,?????(trichuriasis)?
43
1.??
????
????,?3/5????,?2/5??? ?35-50mm,??????? ?30-35mm,??
????????
44
2???
  • ???,???,5222 µm,???,????,????1????,????????

45
?????
  • ???????,?????????????????? ??,?????,?????
  • ?????,?3?,????????????
  • ????,???????,????,10???,????,?????,??????
  • ???????,1-3???????3-5??

46
(No Transcript)
47
??????????
?? ??
???? ?? ??
?????? ?? ??
???? 3W 3W
???? ????? ?????
???? ?? ??
???? ????? ?
?????? 6075? 13?
???? 1? 35?
48
????
  • ? ????
  • ? ????
  • ? ?????
  • ? ??????????????????????????????????,30?

49
???????
????
50
??????
  • ????????
  • ????
  • ???????
  • ?????

?????????
51
???????
  • ??????????????,????
  • ????????????????
  • ?????10??,???4000??
  • ??????????????????????????????
  • ??????????

52
??????
Enterobius vermicularis
????(pinworm),??????(enterobiasis),???????,???????
??,?????????????????????
53
????
?? ???1cm
??
??
54
?????
55
(No Transcript)
56
  • ????
  • ??4?,??,??????20??,????????,?????????????1
    997?6?17????????????1.5,????,??????????,????????
    ??,??????????????1.5????????????????????????,?????
    ?????,????7??????????10.5 mm 2?,11mm 4?,4.3 mm
    1?????????????????,??????,??????????,???????,?????
    ??????????????????????

57
  • ?????
  • ????????,???????
  • ?????????
  • ????????????????
  • ????--??????????
  • ???????
  • ??????(?????)
  • ??????

58
??????
1????????????????? 2?????
?????????? ?????
59
??????
Enterobius vermicularis
????(pinworm),??????(enterobiasis),???????,???????
??,?????????????????????
60
????
?? ???1cm
??
??
61
?????
62
(No Transcript)
63
  • ????
  • ??4?,??,??????20??,????????,?????????????1
    997?6?17????????????1.5,????,??????????,????????
    ??,??????????????1.5????????????????????????,?????
    ?????,????7??????????10.5 mm 2?,11mm 4?,4.3 mm
    1?????????????????,??????,??????????,???????,?????
    ??????????????????????

64
  • ?????
  • ????????,???????
  • ?????????
  • ????????????????
  • ????--??????????
  • ???????
  • ??????(?????)
  • ??????

65
??????
1????????????????? 2?????
?????????? ?????
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