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Case Presentation

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... Control of CINV Olanzapine + Palonosetron + Dexamethasone vs Aprepitant + Palonosetron + Dexamethasone: Study Design Olanzapine as an Antiemetic Case ... – PowerPoint PPT presentation

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Title: Case Presentation


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Case Presentation
4
Discussion of Question 1
5
Discussion of Question 2
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Case Presentation (cont)
7
Discussion of Question 3
8
Focus on Nausea Current Trends in Patient
Assessment and Treatment Approaches
9
Proposed Pathways of Chemotherapy-Induced Emesis
10
Emetic Risk Categories
11
Risk Factors for Chemotherapy-Induced Nausea and
Vomiting
12
Classification of Chemotherapy-Induced Nausea and
Vomiting
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Delayed Emesis
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Treatment Algorithm Control of
Chemotherapy-Induced Emesis
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Serotonin Antagonists and Dosage
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Off-Label Agents for the Control of
Chemotherapy-Induced Nausea
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Gabapentin for the Control of CINV Study Design
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Gabapentin Control of CINV
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Olanzapine Palonosetron Dexamethasone vs
Aprepitant Palonosetron Dexamethasone Study
Design
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Olanzapine as an Antiemetic
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Case Presentation (cont)
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Discussion of Question 4
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Case Presentation (cont)
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Discussion of Question 5
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Discussion of Question 6
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Discussion of Question 7
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Discussion of Question 8
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CINV Links to Anorexia/Cachexia
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Questions to Consider
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Emetic Reflex Arc and Anorexia Similar Pathways
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Anorexia Seems to Improve With Effective
Chemotherapy
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Adjuvant chemotherapy is linked to weight gain.
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Caloric Intake is Not Necessarily
Reduced/Increased With Adjuvant Chemotherapy vs
Localized Treatment
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Point 1 Main Concepts
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Questions to Consider
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Multiple, placebo-controlled clinical trials
suggest the following
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Palliating Anorexia in Cancer Patients
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Megestrol Acetate Appears to Also Help With
Vomiting (This Shouldnt Be Surprising)
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Point 2 Main Concepts
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Recognizing the Importance of Cachexia in Cancer
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