Guideline,NICE ,HTA,Cochrane

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• Guideline,NICE ,HTA,Cochrane
• OVID ?????????
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• - Major MeSH ? Pubmed related ??

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• ?????? Cochrane Library???
• ???? Pubmed ? filter
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• ???? VPN (remote access)
• ????????? (guideline)
• ???? Catmaker ???? paper
• ??? NNT (number needed to treat)
• ??? odds ratio?

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Oxford Center for Evidence-based Medicine Levels
of Evidence (May 2001)
Level Therapy
1a ????? Systematic review, ???? Meta analysis (????????????, ??????)
1b ????, ???? ????????? (Randomized Controlled Trial ,RCT)
1c All or none
2a ????? (????????, ??????)
2b ???? Cohort study ?????????????
2c "Outcomes" Research Ecological studies
3a ????? (??????-????, ??????)
3b ?? - ???? Case-control study
4 ????????? ????????? ??? - ????
5 ???????????, ????, ????, ????, ???????
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Information Seeking Behavior

• Index Medicus vs. browse core journals
• - ?????????? NLM ???
• - 1995 ????? (IE, Netscape, Firefox)
• - Pubmed (free, hyperlink, daily update)
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How to Get the Right Stuff and Avoid the Wrong
Stuff
????????????? ??????????????
?????? Bingo!! a Noise b
?????? Miss c Reject correctly d
??? precision a / (ab) ??? recall a / (ac) Balance between time and information! ??? precision a / (ab) ??? recall a / (ac) Balance between time and information! ??? precision a / (ab) ??? recall a / (ac) Balance between time and information! ??? precision a / (ab) ??? recall a / (ac) Balance between time and information!

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Do Something Is Better Than Do Nothing?

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??????????,???????????????

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Kirklin JW, Akins CW, Blackstone EH et al.
Guidelines and indications for coronary artery
bypass graft surgery a report of the American
College of Cardiology/American Heart Association
Task Force on Assessment of Diagnostic and
Therapeutic Cardiovascular Procedures
(Subcommittee on Coronary Artery Bypass Graft
Surgery). J Am Coll Cardiol 1991 17543 89.
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?cochrane?database, ?neutropathic
pain?search limit ?2003-2004??,??28?
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Tramadol??effect???drug!!
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?????????

• ACP Journal Club (as journal name)
• Evidence-based Medicine (as journal name)
• - Diagnosis
• - Therapeutics
• - Prognosis
• - Quality
• - Economic.

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?????????

• OVID Medline ????
• -- ???? vs. ???? (MeSH)
• -- Explode Focus
• -- Mapping
• -- ????? (adj, adv, near)
• -- ??
• -- ???? (search feedback)
• - ???????????????????
• - Major MeSH ? Pubmed related ??

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Mapping Display
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• ADJ????????,?????????????,?????????????,?????????
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• NEAR/XX??????????????,??????????????????
• ??Truncation
• ??(STEMMING)?? renal tubul,?? renal tubules,
  renal tubular????
• in OVID Medline
• in Pubmed

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?????????????? ???

• The role of glucocorticoids in the management of
  acute exacerbation of COPD
• Ribavirin-induced hemolytic anemia in patients
  with chronic hepatitis C a meta-analysis of
  randomized controlled trials
• The diagnostic accuracy of TB-PCR
• a meta-analysis of prospective cohort studies

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Risk of Ribavirin-induced Hemolytic Anemia in
Enrolled Studies
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The necessary of surgery for asymptomatic
intestinal malrotation

• ??????????
• ???? X??????????
• ??????,???????
• ???????????????
• ????? PICO
• - Population
• - Intervention
• - Comparison
• - Outcome

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Foreword

• ????????????????,???????????????????????????,?????
  ,?????????????,????????????????,??????????????????
  ?,?????????,?????????????,????????????,???????????
  ?????????????(?????,????????????????????)?????????
  ???????,???????????

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Thanks for Your Attention!