Lectures posted online after lecture.

1
Lectures posted online after lecture. Textbook
sections and/or pages posted a few days prior to
each lecture.
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CB 14.3
In many instances there is a unique pattern of
inheritance. Traits disappear and reappear in
new ratios.
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Genotype
Phenotype
CB 14.6
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Human blood types
CB tbl 14.2
AA or AO
BB or BO
AB
OO
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Looking at the past If Frank has B blood
type, his Dad has A blood type, And his Mom has B
blood type Should Frank be worried?
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MomB blood BB or BO
DadA blood AA or AO
possible genotypes
all A / 50 A and 50 O
all B / 50 B and 50 O
Gametes
Frank can be BO B blood
no worries
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We can also predict the future
Fig 2.12
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Inheritance of blood types
Mom AB
Dad AB
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Inheritance of blood types
Mom AB
Dad AB
A or B
Gametes
A or B
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Inheritance of blood types
Mom AB
Dad AB
A or B
A or B
Gametes
Dad
A or B
Chance of each phenotype for each offspring 25
AA 50 AB 25 BB
AA
A or B
AB
Mom
AB
BB
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CB14.7
Testcrossdetermining dominant/ recessive and
zygosity
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Sickle-cell anemia is caused by a point mutation
CB5.21
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Sickled and normal red blood cells
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Sickle-Cell Anemia A dominant or recessive
allele?
Ssickle-cell Hnormal
Mom HS
Dad HS
Dad
H or S
possible offspring 75 Normal 25 Sickle-cell
HS
HH
H or S
Mom
HS
SS
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Coincidence of malaria and sickle-cell anemia
CB 23.13
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Sickle-Cell Anemia A dominant or recessive
allele?
Ssickle-cell Hnormal
Mom HS
Dad HS
possible offspring Oxygen transport 75
Normal 25 Sickle-cell Malaria resistance 75
resistant 25 susceptible
Dad
H or S
HS
HH
H or S
Mom
HS
SS
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Variation in Peas
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CB 14.8
Phenotype
Genotype
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CB 14.8
The inheritance of genes on different
chromo-somes is independent.
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Approximate position of seed color and shape
genes in peas
Gene for seed color
y
Y
r
R
Gene for seed shape
Chrom. 1/7
Chrom. 7/7
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CB 15.2
The inheritance of genes on different chromosomes
is independentindependent assortment
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CB 15.2
meiosis I
meiosis II
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CB 15.2
The inheritance of genes on different chromosomes
is independentindependent assortment
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CB 14.8
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CB 14.9
Inheritance can be predicted by probability
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Probability of a 4 1/6 Probability of two 4s in
a row1/6x1/61/36
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Probability of 3 or 4 1/61/6 1/3
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and multiply
or add
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Huntingtons Disease

• Ddisease
• dnormal

Neurological disease, symptoms begin around 40
years old.
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Ddisease dnormal
Huntingtons Disease
Mom dd
Dad Dd
Dad
D or d
possible offspring 50 Huntingtons 50 Normal
Dd
d or d
dd
Mom
Dd
dd
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Two different people One with Huntingtons
disease Dd Hh One without Huntingtons disease
dd Hh mate. What is the probability that their
offspring will have Huntingtons disease and
sickle cell anemia?(Dd hh)
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Two people One with Huntingtons disease Dd
Hh One without Huntingtons disease dd Hh mate.
What is the probability that their offspring
will have Huntingtons disease and sickle cell
anemia? Dd hh Probability of each
outcome Probability of Dd (Ddxdd)
.5 Probability of hh (HhxHh) .25
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Two people One with Huntingtons disease Dd
Hh One without Huntingtons disease dd Hh mate.
What is the probability that their offspring
will have Huntingtons disease and sickle cell
anemia? Dd hh Probability of each
outcome Probability of Dd (Ddxdd)
.5 Probability of hh (HhxHh) .25 Multiply both
probabilities .25 X.5 12.5 chance Dd hh
offspring
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CB 14.11
Many traits are coded for by more than one gene.
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Eye color One trait controlled by multiple genes
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Lectures posted online after lecture. Textbook
sections and/or pages posted a few days prior to
each lecture.