Introduction to NCBI and Name that Gene

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Introduction to NCBIand Name that Gene
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Access the National Center for Biotechnology
Information www.ncbi.nlm.nih.gov
Established in 1988 National resource for
molecular biology information
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NCBI GenBank database of known nucleotide
and protein sequences PubMed all medically
relevant scientific literature OMIM Online
Mendelian Inheritance in Man reviews all known
info about genetic disorders in man BLAST tool
for retrieval of nucleotide and protein sequences
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Location for GenBank
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All Medically Relevant Published Academic
Literature
More Readable Information about genetic
disorders
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OMIM-all known information (literature and
molecular data) for identified human genes
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Access to DNA and Protein Sequences
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Activity 1
Name That Gene
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Objective Identify a Gene

• Use tools in NCBI website
• Using an unknown DNA sequence, do a BLAST search
• Access Genes Diseases to find
• Symptoms
• Chromosome number
• Gene locus for genetic disorder

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ATGGCGACCCTGGAAAAGCTGATGAAGGCCTTCGAGTCCCTCAAGTCCTT
CCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGC
AGC
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Nucleotide Sequence of Gene can determine of
base pairs in gene
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