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Antiviral drugs

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Title: Antiviral drugs


1
???? Antiviral drugs
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3
  • ?????????????????,????????????????????
  • ???????????????????????????
  • ?????????????????????
  • ?????????????????????????????????

4
  • ??????????????????(???)????????????
  • ??
  • ?????????????
  • ????????
  • ???????????????????????
  • ????????
  • ????,????,????,??,????,????,???

5
  • ????????
  • ???????????????????????????????????????????????
  • ?????????????????????????????
  • ??????????????????????

6
  • ?????????????????
  • ?????????????????????????
  • ?????????????????????????????

7
????(acyclovir,????)????(valaciclovir)
  • ??????
  • ??????????
  • ?????DNA???,????DNA????
  • ????????????
  • ??????
  • ??????????????????????????

8
????(ribavirin,???)
  • ??????
  • ?????????
  • ????DNA?RNA???????
  • ????????????????????????
  • ??????????????????????????
  • ?????????????????
  • ???????????????

9
  • ???(interferon,IFN)
  •  ??????
  • ?????????????
  • IFN????????IFN???????????(Antivirus Protein, AVP
    ) ??2,5-???????????????mRNA?????????????????
    ??????????AVP???????????mRNA??????????,???????

10
  • ????????(T??)???,???????????????,????????????
  • ???????????????,?????????????????

11
?????
?? ?????????????????????2-3?
  • ????? 1918-1919H1N1??????
  • ????2???5000?-1? (1.75-3.50?)
  • ???????----??????
  • ?????23-71
  • ????1957-1958H2N2??????
  • ???100??????6.98?
  • ???????
  • ????1968-1969H3N2??????
  • ?????3.38??
  • ???H5N1????
  • ???(tamiflu,??)?

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???(??????,??)
?????????
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Who should not take Tamiflu? Before taking
Tamiflu, tell your doctor if you
have      kidney disease liver disease
pregnant any other chronic or serious
illnesses. You may not be able to take Tamiflu,
or you may require a dosage adjustment or special
monitoring during treatment.
17
What are the possible side effects of Tamiflu?
Allergic reaction (difficulty breathing closing
of your throat swelling of your lips, tongue, or
face or hives). Other, less serious side
effects may be more likely to occur. nausea,
vomiting, or diarrhea abdominal pain
headache dizziness fatigue insomnia cough or
other respiratory symptoms
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