CLINICAL

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CLINICAL TRANSLATIONAL SCIENCE
AWARDSTransforming Biomedical ResearchTo
Improve the Health of Our Nations People

• Donna Jo McCloskey, Ph.D., RN
• Program Officer
• Clinical Division
• National Center for Research Resources
• mccloskd_at_mail.nih.gov

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Impetus for the CTSA Program

• Integrative
• Across health disciplines
• Between scientific areas
• Into the community
• engagement/participation
• Translational
• Laboratory to Clinic to Community to Laboratory
• Educational
• Scientists
• Health care providers
• Community
• Provides resource infrastructure
• NIH funded research
• Non-NIH funded research
• Public-private partnership

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Clinical and Translational Science Award (U54)
RFA-RM-006-002

• Trans-NIH collaboration
• First RFA released October, 2005
• reviewed in summer of 2006 for October 2006
  funding
• U54 mechanism
• Cooperative agreement between awardee academic
  institution and NIH
• Multi-faceted research program
• Complex award mechanism Combined U54, T32 and
  K12
• 5 year award

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Building a National CTSA Consortium
Case Western Reserve
Albert Einstein
OSU
University of Pittsburgh
Northwestern
University of Michigan
University of Washington
University of Rochester
WA
Harvard Boston University Tufts University
ME
MT
ND
OHSU
MN
OR
VT
WI
Yale
NH
Mayo Clinic
NY
ID
MI
MA
Weill Cornell
SD
Columbia
University of Wisconsin
WY
Rockefeller
Univ. of Utah
IA
NJ
University of Iowa
UC, Davis
University of Pennsylvania
PA
NE
NV
University of Chicago
Univ. of Colorado
UCSF
Johns Hopkins
IL
Indiana University
IN
Washington University, St. Louis
OH
UT
WV
CO
VA
Stanford
KS
MO
CA
KY
Duke
Vanderbilt
UNC
TN
AZ
Scripps
OK
NM
AR
SC
UT Southwestern
Emory
GA
AL
MS
Univ of Alabama at Birmingham
LA
TX
UT San Antonio
AK
UT, Houston
FL
Participating Institutions
HI
Since 2006
Since 2007
Since 2008
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Key Functions
NIH other government agencies
Clinical Research Ethics
Trial Design
Advanced Degree-Granting Programs
Biomedical Informatics
CTSA Academic Center
Industry
Participant Community Involvement
Clinical Resources
Biostatistics
Regulatory Support
Healthcare organizations
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Consortium Governance Organization
Governance for Cooperative Agreement
Governance Manual available at http//ctsaweb.org/
Docs/CTSA_Governance_Manual.pdf
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Consortium Governance Organization
CTSA Community EngagementSteering Committee

• Priorities
• Develop evaluation outcomes and metrics for
  community engagement research
• Share resources and instruments
• Establish a registry of community-generated
  research ideas and needs assessment
• Design educational curriculum

Governance Manual available at http//ctsaweb.org/
Docs/CTSA_Governance_Manual.pdf
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Consortium Governance Organization
CTSA Community Engagement Steering Committee

• Additional Priorities
• Leverage partnerships for funding
• Interact with other CTSA programs
• Foster new research on the dissemination and
  implementation of relevant clinical
  population-based research
• Establish community based advisory boards

Governance Manual available at http//ctsaweb.org/
Docs/CTSA_Governance_Manual.pdf
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Consortium Governance Organization
CTSA Community Engagement Steering Committee

• Recent CTSA Community Engagement Activities
• Established 2 topic-based workgroups
• Regional Workshops Workgroup
• Community-Based Academic and Practice partnership
  Workgroup
• Education Workgroup
• Regional Workshops Jointly Sponsored by NCRR and
  APTR
• Kick-off Workshop May 9th in Bethesda, MD
  Accelerating the Dissemination and Translation
  of Clinical Research into Practice
• Future workshops planned in 5 national regions

Governance Manual available at http//ctsaweb.org/
Docs/CTSA_Governance_Manual.pdf
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http//www.aptrweb.org/workshops/agenda.html
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Community Engagement Milestones

• Established Community Based Advisory Boards
• Performed Community Engagement Needs Assessments
• Established/Leveraged Partnerships for Funding
• Developed Relevant trans-CTSA educational
  curriculum
• Developed a Forum for Sharing Resources/Instrument
  s

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CTSAWeb.org
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• Community Engagement
• Institutional Activities
• National Activities
• Membership
• Meeting schedules and summaries
• http//www.ctsaweb.org/

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CTSAWeb.org
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