SCREENING

1
SPRINT-2 Design (Naïve Study)
72
Weeks 12
28
48
24
Arm 1 SOC Comparator
PEG 1.5RBV4 wk
Follow-up24 wk
Placebo PEG 1.5 ?g/kg weekly RBV 44 wk
CONTROL
SCREENING
TW 8 Undetectable
Arm 2 Response Guided Therapy
Follow-up44 wk
PEG 1.5RBV4 wk
BOC PEG 1.5 ?g/kg RBV24 wk
TW 8 Detectable/TW 24 Undetectable
EXPERIMENTAL ARMS
Follow-up24 wk
Placebo PEG 1.5 ?g/kg RBV 20 wk
Arm 3 SOC Boceprevir
PEG 1.5RBV4 wk
BOC PEG 1.5 ?g/kg RBV 44 wk
Follow-up24 wk