http://etp.ciaa.be

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• http//etp.ciaa.be

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Consumer life goals re food
Be healthy for longer
Be free from Health Problems
Give Children a Good Start
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Huge global issues in nutrition
4bn people affected by malnutrition deserve the
chance to develop physically mentally to get
more out of life.
50 of worlds population have blood cholesterol
thats too high.
30 of worlds population have blood pressure
thats too high.
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Trends in society The other side of the coin

• Ageing population
• Changes in lifestyle and dietary patterns have
  increased the incidence of chronic
  non-communicable diseases including
• Obesity
• Cardiovascular diseases
• Hypertension
• Diabetes mellitus
• Certain cancers

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A vision for improving population health
Green MR and van der Ouderaa F, Nature
Pharmacogenomics - 2003
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ETP Food for Life Vision

• An effective integration of strategically-focussed
  , trans-national, concerted research in the
  nutritional-, food- and consumer sciences and
  food chain management will deliver innovative,
  novel and improved food products for, and to,
  national, regional and global markets in line
  with consumer needs and expectations.
• These products, together with recommended changes
  in dietary regimes and lifestyles, will have a
  positive impact on public health and overall
  quality of life (adding life to years).
• Such targeted activities will support a
  successful and competitive pan-European agro-food
  industry having global business leadership
  securely based on economic growth, technology
  transfer, sustainable food production and
  consumer confidence.

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ETP Food for Life Vision

• An effective integration of strategically-focussed
  , trans-national, concerted research in the
  nutritional-, food- and consumer sciences and
  food chain management will deliver innovative,
  novel and improved food products for, and to,
  national, regional and global markets in line
  with consumer needs and expectations.
• These products, together with recommended changes
  in dietary regimes and lifestyles, will have a
  positive impact on public health and overall
  quality of life (adding life to years).
• Such targeted activities will support a
  successful and competitive pan-European agro-food
  industry having global business leadership
  securely based on economic growth, technology
  transfer, sustainable food production and
  consumer confidence.

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European Technology Platform Food for Life
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Stakeholders proposal for a Strategic
Research Agenda April, 2006
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The key innovation challenges

• The development of this ETP has been driven by
  the activities of its eight Working Groups
• To optimize the synergy of its internal
  interactions, the Stakeholders Strategic
  Research Agenda, SSRA, has been drafted according
  to the seven Key Challenges for Innovation facing
  the European agri-food sector
• These Challenges map closely with the goals and
  deliverables of the individual Working Groups

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Healthy ageing Goal
Add life to years
Well-being/ appearance
Age
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Food Health

• Delivering a healthy diet
• Working group
• Prof Wim Saris, DMS Univ Maastricht, NL (chair)
• Dr Jacqueline Castenmiller, WCFS, NL
  (fascilitator)
• Prof Nils-Georg Asp, LU, SE
• Prof Robert-Jan Brummer, WCFS, NL
• Dr Irene Corthesy, CRN, Nestlé, CH
• Prof Hannelore Daniel, Techn Univ, München, D
• Dr Gerd Hazer, Kraft, D
• Dr Ian Johnson, IFR, Norwich, UK
• Prof Bertold Koletzko, Univ München, D
• Prof Ian Macdonald, Univ Nottingham,UK
• Dr Gert Meijer, Unilever, NL
• Dr Moïse Riboh, Danone, F

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Food Health priority research areas
INFANT
BRAIN FUNCTIONS
IMMUNE- INTESTINAL FUNCTIONS
life-stage
METABOLIC FUNCTIONS
ELDERLY
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How did we work?

• TOWARDS A STRATEGIC RESEARCH AGENDA FOR FOOD,
  NUTRITION HEALTH
• 1. Please define research questions for each cell
  in the table.
• 2. For each of the research questions, describe
• - (Knowledge) deliverables
• - When to reach these deliverables 2010, 2015 or
  2020
• - Bottlenecks to solve the research questions
• - The breakthrough potential on a scale from 1 to
  5 (low to high potential)? This is about the
  potential of the research to contributing to
  breakthrough chances or opening up new horizons
  for application-inspired research.

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How did we work? 2

• Table. Scientific targets

Life cycle Metabolic function Immune function Brain function
Cell plasticity Cell plasticity Cell plasticity
In-utero, new-borns, infants and young children -To optimise development 1 -Early disease prevention minimising risk for later life 2 -Physical activity 3 -Programming and imprinting 4 -Optimal weaning foods to maximise resistance and to minimise food allergy 5 -Immune tolerance 6 -Nutrition and cognitive function 7 -Brain conditioning (e.g., taste perception) 8
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How did we work 3
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Food Health

• Delivering a healthy diet
• Understanding brain function in relation to diet
• Understanding dietary effects on immune and
  intestinal function
• Understanding the link between diet and metabolic
  function (obesity and associated metabolic
  disorders)
• Understanding consumer behaviour in relation to
  health and nutrition

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Goal 1 Understanding brain function in relation
to diet

• Diet and cognitive functions
• Brain conditioning
• Mood and optimal performance
• Prevention of cognitive decline
• Food intake regulation and hunger/satiety
• Nutrition and interorgan signalling - esp
  gut-central nervous system interaction

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Goal 2 Understanding dietary effects on immune
and intestinal function

• Modify systemic inflammatory activity by diet
• Dietary factors that improve barrier functions
• Biomarkers for intestinal health
• Diet before and during pregnancy and lactation -
  immunefunction and allergy
• Improved allergome database for foods

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Goal 3 Understanding the link between diet and
metabolic function (obesity and associated
metabolic disorders

• Early biomarkers of metabolic syndrome
• Individual variations in metabolic energy
  efficiency
• Food components that regulate food intake and
  increase termogenesis
• Intervention strategies
• Counteract age-associated muscle wasting
• Low-grade inflammation - obesity/insulin
  resistance/metabolic syndrome
• Epigenetic events - chronic disease
• Maternal and infant recommendations for opt
  health
• Meal composition and size - energy uptake, satiety

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Goal 4 Understanding consumer behaviour in
relation to health and nutrition

• Key determinants of food habits
• Biological determinants in food choice
• Methodology to understand and quantify
  determinants
• Perception and determinants of healthy
  lifestyle
• Better tools for effective communication
• Consumer knowledge - consumer understanding of
  health schemes, health claims, simplified
  labelling - and personalised nutrition based on
  nutrigenomics

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The integrated picture
science needs
societal needs
consumers needs

• Low health costs
• Healthy ageing
• Improved education on healthy life style
• Extend higher education programmes along
  food-health chain
• Measures of trust
• Improved communication about food and health
  issues
• Involve SMEs in food and health area

• Nutritional systems biology
• New measures for food intake and delivery systems
• New imaging and minimally invasive techniques
• Link databases and datamining of (non) food
  components, intake and health parameters
• Intestinal microbiota function and metagenomics
• Consumer preference, acceptance and needs

• Premium taste and pleasure
• Low salt, low fat foods
• Improved packaging
• Personalised foods
• Increased intestinal and bone health
• Improved immune and cognitive functions
• Life style foods for each life cycle
• Age-related disease prevention

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Horizontal Activities

• The role of Horizontal Activities is to optimise
  the impact of the ETP
• through
• Ensuring internal complementarity
• Minimising gaps or duplication across the SRA
• Establishing effective links with nationally-
  and FP6- funded projects, and other ETPs
• Maximising the effectiveness of European food
  chain science
• Establishing the Mirror Group
• Effecting a dialogue with national funding
  bodies, policy makers and opinion formers, COST,
  EUREKA, ESF etc
• Promoting the ETP
• Gaining the support of all European stakeholders
• Organising national and regional consultations
• Ensuring that the SRA addresses the needs and
  opportunities of all of Europe
• Developing Scenario Studies Raising awareness
  of long-term challenges and opportunities for
  the food chain.

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