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Somites are transient segmented structures derived from paraxial mesoderm.

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Somites are transient segmented structures derived from paraxial mesoderm. contain the progenitors of the axial skeleton, trunk musculature and associated tendons ... – PowerPoint PPT presentation

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Title: Somites are transient segmented structures derived from paraxial mesoderm.


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  • Somites are transient segmented structures
    derived from paraxial mesoderm.
  • contain the progenitors of the axial skeleton,
    trunk musculature and associated tendons, trunk
    dermis, endothelial cells, and meninges of the
    spinal cord

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  • ventromedial part of the somite forms the
    sclerotome
  • the remainder of the somite consists of a dorsal
    epithelial layer called the dermomyotome
  • dermomyotome quickly separates into two
    structures a dermatome and a myotome The
    dermatomes contribute to the dermis (including
    fat and connective tissue) of the neck and the
    back.

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  • The myotomes differentiate into myogenic
    (muscle-producing) cells
  • Each myotome splits into two structures a dorsal
    epimere and a ventral hypomere
  • The epimeres give rise to the deep epaxial
    muscles of the back, including the erector spinae
    and transversospinalis groups.

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  • The hypomeres form the hypaxial muscles of the
    lateral and ventral body wall in the thorax and
    abdomen intercostal muscles,external oblique,
    internal oblique, and transversus abdominis, and
    the rectus abdominis

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  • Cervical regionhypaxial myoblasts form the strap
    muscles of the neck, including the scalene and
    infrahyoid muscles.
  • Lumbar region, the hypomeres form the quadratus
    lumborum muscles.
  • At limb-forming levels, hypaxial myoblasts invade
    the developing limb buds and give rise to the
    limb musculature.

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