Brainstorming

1
Brainstorming
2
Goal

• Identify a use case and create a collaborative
  group to build a POC that demonstrates the
  secondary use of EMR data for patient recruitment
  for clinical trials

3

• Is the use case good?
• Chimezie yes
• Rachel yes
• June yes?
• Aaron yes
• Vijay yes
• Jyotishman yes
• Ronen yes
• Tom Qualified Yes
• Transformation
• George Allen/VA Yes
• Susie share with Lilly development
• Yes
• Don Product uses machine learning
• Qualified yes
• Dan Good use case
• Adrian Good use case
• Alan Yes
• Eric N Yes

4
Issues

• Characteristics of patients may not be available
  in the EMR
• Broadness of Inclusion/Exclusion Criteria
• Make sure you incorporate the hard cases
• Variables of interest
• Some other aspect of EMR shipping to the patient
• Clinical Database and a funder of clinical trial
• Interfaces
• Mapping into EMR system. Need for mapping tools
• Data required for regulatory agencies..
• Interactions with Machine Learnining Social
  Networks
• Metrics of success
• Inter-rater reliability?
• Coverage, etc.
• Feedback
• Explanation, data collection

5
Data Issue

• Vipul Will try to get some data
• Alan choose criteria to reduce the type of
  anonymyzation required
• Need to develop specific criteria and data
  requirements spreadsheet
• K anonymyzation
• Data should come from at least two sources if not
  more

6
Resources

• George Allen college student
• Tom Get back to me
• Ronen Fox Hopefully at least 1
• Jyotishman Get back to me
• Scott Marshall 1 student possible
• Joanne Get back to me
• Aaron Get back
• Michel 2 students or more
• Rachel 1 day/week
• Alan Get back to me
• Eric U Cincinnati Bruce Aronows students
• Amit Sheths students
• Chimezie
• Vipul 1 day/week
• Susie ! Student
• Dan 1 day/week
• Marcus something more concrete
• Adrian Rule bases applications need to define

7
Concrete Project Plan

• Do it on the next Telcon

8
Regulatory Issues

• June Federally mandate barrier Clinicians
  cannot refer patients for research studies
• A researcher can find cohort and go to the
  clinician