Meat, Dairy and Breast Cancer Publication

1
Meat, Dairy and Breast Cancer Publication
Missmer, et al. Meat and dairy food consumption
and breast cancer a pooled analysis of cohort
studies. International Journal of Epidemiology.
2002 31 78-85.
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Cohort Studies in the Pooled Analysis of Meat and
Dairy Intake and Breast Cancer
Sweden Mammography Cohort
Canadian National Breast Screening Study
Nurses Health Study
Netherlands Cohort Study
New York University Womens Health Study
New York State Cohort
Adventist Health Study
Total 351,041 of cases 7,379
Iowa Womens Health Study
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Cohort Studies in the Pooled Analysis of Meat and
Dairy Consumption and Breast Cancer
Study Baseline No. of
Cohort Cases

Adventist Health 15,172
160 Canadian National 56,837 419
Iowa Womens 34,406 1130
Netherlands Cohort 62,377 937
New York State 18,475 367
New York University 13,261 385
Nurses Health (a) 89,046 1023
Nurses Health
(b) 68,817 1638 Sweden Mammography 61,467 1
320
Missmer, et al. 2002
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Median Intakes (g/d) Among
Control Participants
Study Meat Dairy Dairy
fluids solids Adventist Health
25 262 28 Canadian
National 181 247 34 Iowa
Womens 166 250 23 Netherlands
Cohort 106 251 33 New
York State ---- ---- ----
New York University 110 209 24
Nurses Health (a) 215 203 27
Nurses Health (b) 163 231 24
Sweden Mammography 91 219 24
Missmer, et al. 2002
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Pooled Multivariate Relative Risksof Meat and
Breast Cancer
Quartile Total Meat Red Meat White Meat
1 1.00 1.00 1.00 2
1.07 1.00 0.99 3
1.02 0.99 1.03 4
1.08 0.94
1.02 (0.98-1.19) (0.87-1.02)
(0.91-1.13) p for trend 0.13
0.13 0.21
Missmer, et al. 2002
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Study-Specific Relative Risks for Red Meat and
Breast Cancer (Quartile 4 vs. 1)
Adventist
Canada
Iowa
Netherlands
NY State
NY University
Nurses' (a)
Nurses' (b)
Sweden
Combined
.5
1
5
Relative Risk
Missmer, et al. 2002
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Pooled Multivariate Relative Risks of Specific
Red Meats and Breast Cancer
Food item RR (95 CI)
(increment 100g/d) Ground beef 1.09
(0.89-1.34) Organ meats 1.07
(0.61-1.88) Processed meats 0.98
(0.96-1.00) Bacon 0.99 (0.89-1.09) Sausage
0.94 (0.83-1.07) Hot dogs 0.75
(0.39-1.44)
Missmer, et al. 2002
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Pooled Multivariate Relative Risks of Specific
White Meats and Breast Cancer
Food item RR (95 CI)
(increment 100 g/d) Poultry 1.05
(0.96-1.13) Seafood 1.01 (0.87-1.16) Fish
1.01 (0.87-1.17) Shellfish 0.77
(0.39-1.53) Eggs 1.22 (1.03-1.45)
Missmer, et al. 2002
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Pooled Multivariate Relative Risksof Dairy
Products and Breast Cancer
Quartile Fluids Solids 1 1.00
1.00 2 1.00 1.02
3 0.92 0.94 4 0.93
1.01 (0.84-1.03)
(0.93-1.09) p for trend 0.09
0.94
Missmer, et al. 2002
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Pooled Multivariate Relative Risksof Specific
Dairy Items and Breast Cancer
RR (95 CI) (increment 100 g/d)
Cheese 1.16 (0.98-1.37) Cottage cheese
0.97 (0.85-1.09) Ice cream 1.03
(0.88-1.22) Milk 0.99 (0.97-1.00) Yogurt
0.98 (0.94-1.01)
Missmer, et al. 2002
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Pooled Multivariate Relative Risks of Breast
Cancer and Meat Consumption by Menopausal Status
RR (95 CI) p-for
(increment 100 g/d)
interaction Red meat
Premeno. 0.97
(0.79-1.20) Postmeno.
0.97 (0.91-1.03) 0.85 White meat
Premeno. 0.99 (0.79-1.25)
Postmeno. 1.05 (0.97-1.15) 0.36 Total
Meat Premeno. 1.00 (0.87-1.14)
Postmeno. 1.04 (0.99-1.09) 0.99
Missmer, et al. 2002
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Pooled Multivariate Relative Risk of Breast
Cancer and Dairy Consumption by Menopausal Status
RR (95 CI) p-for
(increment 100 g/d) interaction Total
dairy fluids Premeno.
0.96 (0.90-1.02)
Postmeno. 1.00 (0.98-1.01) 0.53 Total
dairy solids Premeno. 0.87 (0.68-1.11)
Postmeno. 1.05 (0.94-1.16)
0.73
Missmer, et al. 2002