Title: The NMDA Receptor
1Chapter 8 The NMDA Receptor
From Mechanisms of Memory, second edition By J.
David Sweatt, Ph.D.
2The NMDA Receptor
3Loss of the NMDA Receptor Selectivity in
Hippocampal Area CA1 Leads to Selective Deficits
in LTP
Figure 1
4Loss of the NMDA Receptor in Area CA1 Blocks
Learning in the Morris Water Maze
Figure 2
5NMDA Receptors are Involved in Synaptic
Plasticity
Figure 3
6NMDA Receptor and Binding Sites for Regulatory
Molecules
Figure 4
7Direct Modulators of the NMDA Receptor
Table 1
8Summary of Molecular Composition of the NMDAR
Supramolecular Complex
Figure 5
9LTP Induction Machinery
Figure 6
10TABLE II MECHANISMS UPSTREAM OF THE NMDA
RECEPTOR INVOLVED IN MEMBRANE DEPOLARIZATION
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13Receptor Modulation of the NMDA Receptor
Figure 7
14Interactions among Integrins and Intracellular
Effectors
Figure 8
15PSD-95 as an Anchoring Protein
Figure 9