OPTICAL QUALITY OF DUAL-OPTIC ACCOMMODATING INTRAOCULAR LENS

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OPTICAL QUALITY OF DUAL-OPTIC ACCOMMODATING
INTRAOCULAR LENS
The Synchrony IOL is not currently FDA-approved

• Andrea Galvis, MD 1,3 a
• Ivan Ossma, MD MPH MSc 1,2, a
• Sanjeev Kasthurirangan, PhD 4, b

1 Fundacion Valle del Lili, Cali-Colombia 2
Universidad Industrial de Santander,
Bucaramanga-Colombia 3 Universidad Autonoma de
Bucaramanga, Bucaramanga-Colombia 4 Abbott
Medical Optics Inc, Irvine, USA Financial
Disclosure a Consultant Abbott Medical Optics
b Scientist at Abbott Medical Optics Inc.
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Synchrony Design
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• Anterior Optic 32 Diopters
• Posterior Optic Divergent (negative)

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Study Purpose

• Compare Optical Quality Pseudophakic Eyes
• Monofocal IOL
• Synchrony Dual Optic Accommodating IOL
• Parameters
• Objective iTrace aberrometry
• Custom Matlab Software to calculate MTF
• Subjective Contrast Sensitivity Testing
• Optec 6500

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Study Population

• iTrace aberrometry
• Cycloplegia
• 3 mm zone
• Matlab Software to calculate MTF
• Monofocal IOL 15 subjects (30 eyes)
• Synchrony IOL 16 subjects (32 eyes)

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iTrace - Matlab conversion
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Results
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Objective Measurements3 mm pupil
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Best-focus MTF 3 mm pupil
Differences are less than 10
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Mesopic Contrast Sensitivity
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p0.61 Wilcoxon Rank Sum Test
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Discussion

• Dual Optic Design DOES NOT affect optical or
  retinal image quality of the eye
• Objective evidence (iTrace, MTF)
• Subjective evidence (CSF)
• Contrast sensitivity of Synchrony is equivalent
  to that of monofocal IOLs

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Discussion

• Effect of the slight spherical aberration on
  Synchrony would only yield 0.42 D of increased
  depth of focus
• Calculations based on Rochas work
• The improved near vision of Synchrony patients
  MOST LIKELY due to true accommodation

Rocha KM. Using Adaptive Optics Simultion to
Explore the Effect of Higher Order Aberrations on
Depth of Focus for the Correction of Presbyopia.
Wavefront Congress 2008
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Conclusion

• Quality of Vision of Synchrony IOL similar to
  standard monofocal IOLs
• Measured Subjectively
• Measured Objectively
• Improved Near Vision with Synchrony
• Not related to increased depth of focus