Acne Vulgaris

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Acne Vulgaris
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Objectives

• Know the epidemiology and causes of acne
• Know the types of acne lesions
• Differentiate adenoma sebaceum from acne
• Plan an appropriate treatment of acne

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Epidemiology

• Most common skin disease treated by physicians
• 14.5 million visits to physician/year
• 17 million Americans have acne
• 85 of adolescents between 15 and 17
• gt 1 billion dollars in health costs per year
• 100 million/year in over the counter products

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Pathophysiology
Evolution of acne lesions
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Pathophysiology of Acne
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Classification of Lesions
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• The next slides are visual examples of the type
  of lesions in acne. Have fun first guessing the
  types of lesions as the answer will only appear
  after you click.

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Non-inflammatory comedonalWhiteheads and
Blackheads
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Papular Inflammatory
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Papular and Pustular Inflammatory
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Papules, Nodules, and Cysts
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Severe Nodular and Cystic
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Adenoma Sebaceum
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Adenoma Sebaceum

• Most common skin manifestation of tuberous
  sclerosis
• 1-5 mm yellow-pink papules with fine
  telangiectasia
• Benign hamartomas composed of fibrous and
  vascular tissue (angiofibromas)
• May first appear during childhood or early
  adolescence ? Differentiate from Acne!!!

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Classification of Severity
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How Treatment Works
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Major Pathophysiologic Features of Acne and Drugs
That Affect Them
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Topical and Systemic Antibiotics Used to Treat
Acne
Leyden J. N Engl J Med 19973361156-1162
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